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Results for “Myotonic Dystrophy”

142 trials

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Showing 20 of 142 results

Large-scale testing (Phase 3)Looking for participantsNCT05532813
What this trial is testing

Evaluation of the Efficacy and Safety of Metformin in the Myotonic Dystrophy Type 1 (Steinert's Disease)

Who this might be right for
Steinert's DiseaseMyotonic Dystrophy 1Metformin
Assistance Publique - Hôpitaux de Paris 142
Not applicableEnrolling By InvitationNCT06605612
What this trial is testing

Development and Validation of the FBIndex to Determine the Risk of Falls for Patients With Neuromuscular Disorders

Who this might be right for
Inclusion Body MyositisMyotonic DystrophyLimb-girdle and Facioscapulohumeral Muscular Dystrophies+9 more
LMU Klinikum 108
Not applicableNot Yet RecruitingNCT07732439
What this trial is testing

An Ambispective Natural History Study in Myotonic Dystrophy Patients Linking Retrospective Data Captured From the DM-Scope Registry With a Prospective 24-month Follow-up Period

Who this might be right for
Myotonic Dystrophy 1Myotonic Dystrophy 2
Lupin Ltd. 100
Not applicableStudy completedNCT04616807
What this trial is testing

An Observational Study in Adult Patients With Non-dystrophic Myotonic Disorders

Who this might be right for
Myotonic Dystrophy
Lupin Ltd. 53
Not applicableLooking for participantsNCT06716931
What this trial is testing

Investigating Exercise in Myotonic Dystrophy Type 2 (DM2)

Who this might be right for
Myotonic Dystrophy 2
Massachusetts General Hospital 24
Not applicableStudy completedNCT01242007
What this trial is testing

Postural Spirometry Changes in Ambulatory Myotonic Dystrophy Patients

Who this might be right for
Myotonic Dystrophy
University of Nancy 58
Large-scale testing (Phase 3)Study completedNCT01421992
What this trial is testing

Methylphenidate in Myotonic Dystrophy Type 1

Who this might be right for
Dystrophia Myotonica 1
Laval University 28
Testing effectiveness (Phase 2)Looking for participantsNCT06138743
What this trial is testing

Study of SRP-1003 in Participants With Type 1 Myotonic Dystrophy

Who this might be right for
Myotonic Dystrophy 1
Sarepta Therapeutics, Inc. 78
Not applicableStudy completedNCT05400629
What this trial is testing

Effects of a 12-week Strength Training Program in Women With Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy 1
Université de Sherbrooke 12
Testing effectiveness (Phase 2)Study completedNCT04886518
What this trial is testing

Safety and Efficacy of Pitolisant on Excessive Daytime Sleepiness and Other Non-Muscular Symptoms in Patients With Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy 1Excessive Daytime Sleepiness
Harmony Biosciences Management, Inc. 30
Early research (Phase 1)Study completedNCT06204809
What this trial is testing

Safety, Tolerability, PK, and PD Study of PGN-EDODM1 in Participants With Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy 1
PepGen Inc 24
Not applicableStudy completedNCT03603171
What this trial is testing

Clinical Outcome Measures in Myotonic Dystrophy Type 2

Who this might be right for
Myotonic Dystrophy Type 2
Prof. Dr. Benedikt Schoser 60
Not applicableLooking for participantsNCT06833489
What this trial is testing

Transcriptomic Analysis to Put an End to Misdiagnosis in Patients With Rare Muscle Diseases

Who this might be right for
Rare Genetic Muscle DiseasesMuscular Dystrophy, DuchenneMuscular Dystrophy, Becker+2 more
Assistance Publique Hopitaux De Marseille 50
Not applicableStudy completedNCT05890833
What this trial is testing

The Risk of Falls Index for Patients With Neuromuscular Disorders

Who this might be right for
Inclusion Body MyositisMyotonic DystrophyFacioscapulohumeral Muscular Dystrophies+3 more
LMU Klinikum 30
Testing effectiveness (Phase 2)Looking for participantsNCT06844214
What this trial is testing

Investigate the Safety, Tolerability, and Efficacy of SAR446268, an Adeno-associated Viral Vector-mediated Gene Therapy in Participants Aged 10 to 55 Years of Age With Non-congenital Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy
Sanofi 32
Not applicableLooking for participantsNCT00272883
What this trial is testing

Molecular and Genetic Studies of Congenital Myopathies

Who this might be right for
Central Core DiseaseCentronuclear MyopathyCongenital Fiber Type Disproportion+5 more
Boston Children's Hospital 4,000
Large-scale testing (Phase 3)WithdrawnNCT04700046
What this trial is testing

Study to Investigate the Efficacy and Safety of Mexiletine in Patients With Myotonic Dystrophy Type 1 and Type 2

Who this might be right for
Myotonic Dystrophy Type 1 and Type 2
Lupin Ltd.
Not applicableStudy completedNCT03589677
What this trial is testing

Brain Involvement in Myotonic Dystrophy Type I: From Functional Neuroimaging to the Impact on Quality of Life

Who this might be right for
Myotonic Dystrophy Type 1 (DM1)
IRCCS San Camillo, Venezia, Italy 50
Not applicableStudy completedNCT04835298
What this trial is testing

Breathlessness Assessment in Adult Patients With Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy Type 1 (DM1)
CHU de Reims 34
Large-scale testing (Phase 3)Enrolling By InvitationNCT07008469
What this trial is testing

Global Open-Label Extension Study of Del-desiran for the Treatment of DM1

Who this might be right for
Myotonic Dystrophy Type 1DM1Myotonic Dystrophy+5 more
Avidity Biosciences, Inc. 199
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