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Results for “NLRP3”

109 trials

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Showing 20 of 109 results

Early research (Phase 1)Looking for participantsNCT07247266
What this trial is testing

Study to Evaluate the Safety, Tolerability, Efficacy and Pharmacokinetics of JTE-162 in Subjects With Cryopyrin-Associated Periodic Syndrome (CAPS)

Who this might be right for
Cryopyrin-associated Periodic Syndromes (CAPS)
Akros Pharma Inc. 5
Large-scale testing (Phase 3)Study completedNCT01105507
What this trial is testing

The Safety and Efficacy of Canakinumab in Patients Aged 4 Years or Older Diagnosed With Cryopyrin-associated Periodic Syndromes (CAPS) in Canada

Who this might be right for
Cryopyrin Associated Periodic Syndrome
Novartis Pharmaceuticals 4
Testing effectiveness (Phase 2)Study completedNCT01045772
What this trial is testing

Safety and Tolerability of Rilonacept in Muckle-Wells Syndrome (MWS) or Schnitzler Syndrome (SchS)

Who this might be right for
Muckle-Wells SyndromeSchnitzler Syndrome
Charite University, Berlin, Germany 10
Not applicableUnknownNCT05077007
What this trial is testing

Evaluation of Renal Damage After PCNL and ESWL Using Novel RNA Based Biomarkers

Who this might be right for
Acute Kidney InjuryRenal CalculiPercutaneous Nephrolithotomy+1 more
Ain Shams University 75
Not applicableNot Yet RecruitingNCT06351722
What this trial is testing

Non-surgical Periodontal Treatment in Smokers on SIRT-1, NLRP3 Inflammasome and LncRNAs

Who this might be right for
Periodontitis, Adult
Necmettin Erbakan University 100
Not applicableNot Yet RecruitingNCT05292768
What this trial is testing

Are Mast Cells Involved in Autoinflammatory Diseases

Who this might be right for
Autoinflammatory DiseaseFMFTRAPS+3 more
Assistance Publique - Hôpitaux de Paris 590
Early research (Phase 1)Study completedNCT04015076
What this trial is testing

Safety and Tolerability, Pharmacokinetic and Pharmacodynamic Study With Inzomelid

Who this might be right for
Healthy
Inflazome UK Ltd 80
Not applicableUnknownNCT03566615
What this trial is testing

Does the Cap Increase the Finding of Polyps When Water Exchange Colonoscopy is Used

Who this might be right for
ColonoscopyPolyp of Colon
VA Greater Los Angeles Healthcare System 1,630
Not applicableStudy completedNCT02719899
What this trial is testing

Effect of Fasting and Refeeding on T-cell Fate

Who this might be right for
AsthmaInflammation
National Heart, Lung, and Blood Institute (NHLBI) 28
Testing effectiveness (Phase 2)Study completedNCT04886258
What this trial is testing

Study of Efficacy, Safety and Tolerability of DFV890 in Patients With Knee Osteoarthritis

Who this might be right for
Symptomatic Knee Osteoarthritis
Novartis Pharmaceuticals 115
Large-scale testing (Phase 3)Study completedNCT02334748
What this trial is testing

Canakinumab in Patients With Systemic Juvenile Idiopathic Arthritis or Hereditary Periodic Fevers Who Participated in the CACZ885G2301E1, CACZ885G2306 or CACZ885N2301 Studies

Who this might be right for
Systemic Juvenile Idiopathic ArthritisHereditary Periodic Fevers
Novartis Pharmaceuticals 31
Not applicableStudy completedNCT04191642
What this trial is testing

Correlation of NLRP3 With Cognitive Dysfunction Early After Heart Valve Replacement Surgery

Who this might be right for
InflammasomesCognitive DysfunctionPyrin Domain-Containing 3 Protein+1 more
General Hospital of Ningxia Medical University 75
Early research (Phase 1)Active Not RecruitingNCT05552469
What this trial is testing

Dose Optimization and Expansion Study of DFV890 in Adult Patients With Myeloid Diseases

Who this might be right for
Myeloid Diseases
Novartis Pharmaceuticals 105
Early research (Phase 1)Study completedNCT04086602
What this trial is testing

Safety and Tolerability, Pharmacokinetic and Pharmacodynamic Study With IZD334

Who this might be right for
Healthy VolunteersCryopyrin Associated Periodic Syndrome
Inflazome UK Ltd 64
Not applicableWithdrawnNCT04432337
What this trial is testing

Role of Type 2 Diabetes in Potentiating the Inflammatory Response Post Extracorporeal Circulation After Cardiac Surgery

Who this might be right for
Inflammatory ResponseExtracorporeal Circulation; ComplicationsCardiac Surgery+1 more
University Hospital Center of Martinique
Large-scale testing (Phase 3)Looking for participantsNCT05658575
What this trial is testing

Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare

Who this might be right for
Acute Gout FlareGout AttackGout Flare+4 more
Olatec Therapeutics LLC 300
Post-approval studies (Phase 4)Study completedNCT05130892
What this trial is testing

Effect of Inflammasome Inhibitor on hsCRP in Patients After PCI

Who this might be right for
NLRP3hsCRPPercutaneous Coronary Intervention
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 132
Testing effectiveness (Phase 2)Study completedNCT06556173
What this trial is testing

Phase 2a Study of VTX3232 in Parkinson's Disease

Who this might be right for
Idiopathic Parkinson Disease
Zomagen Biosciences Ltd. 11
Early research (Phase 1)Study completedNCT04972188
What this trial is testing

A Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of ZYIL1 Following Oral Administration in Healthy Volunteers

Who this might be right for
Healthy
Zydus Lifesciences Limited 18
Early research (Phase 1)Study completedNCT06675175
What this trial is testing

A Phase 1b Study to Assess the Safety, Tolerability, and Pharmacodynamics of AZD4144 in Participants With Established Atherosclerotic Cardiovascular and Chronic Kidney Disease.

Who this might be right for
Chronic Kidney DiseaseAtherosclerotic Cardiovascular Disease
AstraZeneca 29
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