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Results for “NLRP3”

110 trials

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Showing 20 of 110 results

Not applicableEnded earlyNCT03219918
What this trial is testing

Adenoma Detection Rate in Colonoscopy Performed With EndoRings

Who this might be right for
Colorectal AdenomaColorectal Neoplasms
Zealand University Hospital 97
Not applicableNot Yet RecruitingNCT06351722
What this trial is testing

Non-surgical Periodontal Treatment in Smokers on SIRT-1, NLRP3 Inflammasome and LncRNAs

Who this might be right for
Periodontitis, Adult
Necmettin Erbakan University 100
Early research (Phase 1)Study completedNCT02175056
What this trial is testing

A Dose-Block Randomized, Placebo Controlled (Double-blind), Active Controlled(Open-label), Dose-escalation Study

Who this might be right for
Healthy Volunteers
Handok Inc. 58
Testing effectiveness (Phase 2)Looking for participantsNCT07157735
What this trial is testing

A Trial to Test the Use of Dapansutrile, an Anti-inflammatory Medication, in People With Parkinson's Disease

Who this might be right for
Parkinson Disease
Cambridge University Hospitals NHS Foundation Trust 36
Testing effectiveness (Phase 2)Study completedNCT05781698
What this trial is testing

Repurposing Fenofibrate in Modulating mTOR/NLRP3 Inflammasome in Patients With Ulcerative Colitis

Who this might be right for
Inflammatory Bowel Diseases
Tanta University 60
Not applicableStudy completedNCT03460444
What this trial is testing

The Effect of Raising Ketones Directly With MCT Oil on Inflammation in Healthy Young Adults

Who this might be right for
MCT Oil Supplementation
University of British Columbia 15
Post-approval studies (Phase 4)Study completedNCT05130892
What this trial is testing

Effect of Inflammasome Inhibitor on hsCRP in Patients After PCI

Who this might be right for
NLRP3hsCRPPercutaneous Coronary Intervention
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 132
Not applicableStudy completedNCT05128292
What this trial is testing

Effect of CoQ10 Plus Selenium Supplementation on Clinical Outcomes and Biochemical Markers in ME/CFS (CoSeME Study)

Who this might be right for
Myalgic Encephalomyelitis
Hospital Universitari Vall d'Hebron Research Institute 42
Early research (Phase 1)Looking for participantsNCT06974877
What this trial is testing

Repeat PET/CT Imaging in People With CAPS and Anakinra-Induced Amyloidosis Using an Amyloid-Reactive Peptide to Measure Changes in Organ-Specific Amyloid Load

Who this might be right for
Cryopyrin-Associated Periodic SyndromesAmyloidosis
National Institute of Allergy and Infectious Diseases (NIAID) 30
Testing effectiveness (Phase 2)WithdrawnNCT01211977
What this trial is testing

A Pilot Study of XOMA 052 in Familial Cold Autoinflammatory Syndrome / Muckle-Wells Syndrome and Behcet's Disease

Who this might be right for
Muckle Wells SyndromeAutoinflammatoryBehcet's Disease
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Testing effectiveness (Phase 2)Study completedNCT06771115
What this trial is testing

Phase 2a Placebo-Controlled Study of VTX3232 Alone or in Combination With Semaglutide in Obesity

Who this might be right for
Obesity
Zomagen Biosciences Ltd. 176
Testing effectiveness (Phase 2)Study completedNCT04868968
What this trial is testing

Study of Safety, Tolerability and Efficacy of DFV890 in Participants With Familial Cold Auto-inflammatory Syndrome (FCAS)

Who this might be right for
Familial Cold Autoinflammatory Syndrome
Novartis Pharmaceuticals 4
Large-scale testing (Phase 3)Looking for participantsNCT05658575
What this trial is testing

Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare

Who this might be right for
Acute Gout FlareGout AttackGout Flare+4 more
Olatec Therapeutics LLC 300
Not applicableStudy completedNCT04728165
What this trial is testing

Anti-Inflammatory Effects of Time-Restricted Feeding

Who this might be right for
PsoriasisSystemic Inflammation
National Heart, Lung, and Blood Institute (NHLBI) 27
Not applicableStudy completedNCT06986837
What this trial is testing

Role of Inflammasome in Platelet Activation in Sickle Cell Disease Patient

Who this might be right for
Sickle Cell Disease
Centre Hospitalier Universitaire de la Guadeloupe 92
Testing effectiveness (Phase 2)Active Not RecruitingNCT07055516
What this trial is testing

Evaluate the Efficacy and Safety of NT-0796 in Participants With Obesity With or Without Type 2 Diabetes Mellitus

Who this might be right for
Obesity and Type 2 Diabetes
NodThera Limited 176
Not applicableStudy completedNCT02466217
What this trial is testing

Phenomics in Autoimmune and Inflammatory Diseases

Who this might be right for
Healthy VolunteerRheumatoid ArthritisAnkylosing Spondylitis+10 more
Assistance Publique - Hôpitaux de Paris 537
Early research (Phase 1)Study completedNCT04015076
What this trial is testing

Safety and Tolerability, Pharmacokinetic and Pharmacodynamic Study With Inzomelid

Who this might be right for
Healthy
Inflazome UK Ltd 80
Not applicableUnknownNCT04079426
What this trial is testing

Tetracycline to Limit the Innate Immune Response in Acute Respiratory Distress Syndrome

Who this might be right for
Adult Respiratory Distress SyndromePneumoniaSepsis
University of Bonn 50
Early research (Phase 1)Looking for participantsNCT07247266
What this trial is testing

Study to Evaluate the Safety, Tolerability, Efficacy and Pharmacokinetics of JTE-162 in Subjects With Cryopyrin-Associated Periodic Syndrome (CAPS)

Who this might be right for
Cryopyrin-associated Periodic Syndromes (CAPS)
Akros Pharma Inc. 5
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