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Results for “NLRP3”

119 trials

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Showing 20 of 119 results

Large-scale testing (Phase 3)Study completedNCT01302860
What this trial is testing

Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease

Who this might be right for
Cryopyrin-associated Periodic SyndromesFamilial Cold Autoinflammatory SyndromeMuckle-Wells Syndrome+1 more
Novartis Pharmaceuticals 17
Not applicableNot Yet RecruitingNCT07326839
What this trial is testing

Orlistat and Weight Management for Uric Acid Control in Obese Gout: A RCT

Who this might be right for
GoutObesity
XueMei Guo 120
Not applicableLooking for participantsNCT06544018
What this trial is testing

Circadian Rhythm Deregulation in Patients With CAPS

Who this might be right for
Cryopyrin Associated Periodic SyndromeFamilial Cold UrticariaMuckle-Wells Syndrome+1 more
Hospices Civils de Lyon 30
Large-scale testing (Phase 3)Study completedNCT00465985
What this trial is testing

Efficacy, Safety, and Tolerability of ACZ885 in Patients With Muckle-Wells Syndrome

Who this might be right for
Muckle Wells Syndrome
Novartis 35
Not applicableUnknownNCT05744297
What this trial is testing

NLRP3 Inflammasome Activation Among Patients During Acute Gout Flares

Who this might be right for
Gout Arthritis
Centre Hospitalier Saint Joseph Saint Luc de Lyon 10
Not applicableLooking for participantsNCT07120711
What this trial is testing

EGR2 and NLRP3 Pathways in Obstructive Sleep Apnea-Related Cognitive and Mood Disorders

Who this might be right for
Obstructive Sleep Apnea-Hypopnea SyndromeAnxiety DisordersDepressive Disorders
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 1,000
Not applicableStudy completedNCT04635878
What this trial is testing

INFLAmmasomes NLRP3 in Platelets and Leukocytes During SEPSIS in Intensive Care Unit

Who this might be right for
Sepsis
University Hospital, Toulouse 11
Not applicableLooking for participantsNCT06838143
What this trial is testing

Ilaris NIS in Korea

Who this might be right for
Hereditary Periodic Fever SyndromesCryopyrin-associated Periodic Syndromes (CAPS)Colchicine Resistance Familial Mediterranean Fever (crFMF)+3 more
Novartis Pharmaceuticals 25
Not applicableUnknownNCT04127487
What this trial is testing

Quantification of NLRP3 (rs4612666) and CARD8 Gene (rs2043211) in Generalized Chronic Periodontitis Subjects

Who this might be right for
Periodontal DiseasesCoronary Artery Disease
Meenakshi Ammal Dental College and Hospital 70
Testing effectiveness (Phase 2)Study completedNCT00487708
What this trial is testing

Safety, Efficacy, Pharmacokinetics, Pharmacodynamics of ACZ885 in Patients With NALP3 Mutations and Clinical Symptoms

Who this might be right for
NALP3 Mutation
Novartis Pharmaceuticals 34
Not applicableEnded earlyNCT03219918
What this trial is testing

Adenoma Detection Rate in Colonoscopy Performed With EndoRings

Who this might be right for
Colorectal AdenomaColorectal Neoplasms
Zealand University Hospital 97
Not applicableStudy completedNCT02122575
What this trial is testing

Effect of Fasting on the NLRP3 Inflammasome

Who this might be right for
Cardiovascular DiseaseInflammatory Disease
National Heart, Lung, and Blood Institute (NHLBI) 23
Testing effectiveness (Phase 2)Ended earlyNCT05237713
What this trial is testing

Efficacy and Safety of Canakinumab for the Treatment of Anemia in LR-MDS Patients

Who this might be right for
AnemiaMyelodysplastic Syndromes
University of Leipzig 10
Testing effectiveness (Phase 2)Ended earlyNCT06822517
What this trial is testing

A Phase 1b Study of the NLRP3 Inhibitor VENT-02 in Patients With Mild to Moderate Parkinson's Disease

Who this might be right for
Parkinson Disease
Ventus Therapeutics U.S., Inc. 29
Testing effectiveness (Phase 2)Study completedNCT05567068
What this trial is testing

Atorvastatin Efficacy and Safety in Patients With Ulcerative Colitis

Who this might be right for
Inflammatory Bowel Diseases
Tanta University 54
Large-scale testing (Phase 3)Looking for participantsNCT05658575
What this trial is testing

Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare

Who this might be right for
Acute Gout FlareGout AttackGout Flare+4 more
Olatec Therapeutics, Inc. 300
Not applicableStudy completedNCT03460444
What this trial is testing

The Effect of Raising Ketones Directly With MCT Oil on Inflammation in Healthy Young Adults

Who this might be right for
MCT Oil Supplementation
University of British Columbia 15
Testing effectiveness (Phase 2)WithdrawnNCT01211977
What this trial is testing

A Pilot Study of XOMA 052 in Familial Cold Autoinflammatory Syndrome / Muckle-Wells Syndrome and Behcet's Disease

Who this might be right for
Muckle Wells SyndromeAutoinflammatoryBehcet's Disease
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Early research (Phase 1)Looking for participantsNCT07685600
What this trial is testing

Investigating the Effect of Itraconazole on the Pharmacokinetics of AZD4144 in Healthy Participants

Who this might be right for
Healthy
AstraZeneca 32
Not applicableUnknownNCT05493592
What this trial is testing

Pigeon Peas (Cajanus Cajan) : a Natural Anti-inflammatory Facilitating Weight Loss in Obese Patients Returning to Sport?

Who this might be right for
Severe Obesity
University Hospital Center of Martinique 124
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