Early research (Phase 1)Not Yet RecruitingNCT07795762What this trial is testingEplerenone and IOP in Healthy AdultsWho this might be right forIntraocular Pressure (IOP)Healthy Adult University of Florida 30
Large-scale testing (Phase 3)Study completedNCT02807987What this trial is testingStudy of CS-3150 in Combination With ARB or ACE Inhibitor in Hypertensive Patients With Moderate Renal ImpairmentWho this might be right forHypertension With Moderate Renal Impairment Daiichi Sankyo Co., Ltd. 58
Testing effectiveness (Phase 2)Looking for participantsNCT07238400What this trial is testingCardiac Effects of Mineralocorticoid Receptor Antagonism After PreeclampsiaWho this might be right forHypertension Massachusetts General Hospital 90
Not applicableStudy completedNCT03062150What this trial is testingMineralocorticoid Receptor, NMDA Receptor and Cognitive Function in DepressionWho this might be right forMajor Depression Charite University, Berlin, Germany 232
Not applicableNot Yet RecruitingNCT07775482What this trial is testingFinerenone for AKI: a Multicenter, Randomized, Placebo-Controlled Feasibility Pilot TrialWho this might be right forAcute Kidney InjuryRenal Insufficiency,ChronicKidney Diseases Jean-Maxime Côté 72
Large-scale testing (Phase 3)Study completedNCT01319344What this trial is testingEffect of Eplerenone on Endothelial Function in Metabolic SyndromeWho this might be right forMetabolic SyndromeEndothelial Dysfunction University of Erlangen-Nürnberg Medical School 42
Large-scale testing (Phase 3)Study completedNCT02040441What this trial is testingProteomic Prediction and Renin Angiotensin Aldosterone System Inhibition Prevention Of Early Diabetic nephRopathy In TYpe 2 Diabetic Patients With NormoalbuminuriaWho this might be right forDiabetic NephropathyDiabetic Retinopathy Peter Rossing 1,777
Large-scale testing (Phase 3)Study completedNCT02807974What this trial is testingStudy of CS-3150 in Hypertensive Patients With Type 2 Diabetes and AlbuminuriaWho this might be right forHypertension Daiichi Sankyo Co., Ltd. 51
Early research (Phase 1)Ended earlyNCT03682497What this trial is testingStudy in HFpEF Patients to Compare the Effect of AZD9977 and Spironolactone on Serum PotassiumWho this might be right forHeart Failure AstraZeneca 68
Early research (Phase 1)Study completedNCT06649409What this trial is testingEvaluation of Vamorolone Mineralocorticoid Receptor Antagonism in Healthy SubjectsWho this might be right forPharmacodynamic Santhera Pharmaceuticals 30
Testing effectiveness (Phase 2)Study completedNCT05884866What this trial is testingInvestigate the Mechanistic Effects of Dapagliflozin Alone or in Combination With Balcinrenone, Compared to Balcinrenone and Placebo on Body Fluid and Electrolyte Handling and Energy Metabolism in Participants Over 50 Years of Age With Chronic Kidney Disease.Who this might be right forChronic Renal FailureMechanistic Effects of SGLT2 Inhibition and/ or MR Antagonism on Body Fluid and Electrolyte HomeostatisChronic Kidney Disease Stage 3+1 more Klinikum Nürnberg
Early research (Phase 1)Study completedNCT06979388What this trial is testingInvestigate the Effect of Food on Balcinrenone/Dapagliflozin Pharmacokinetics in Fed and Fasted State and Pharmacokinetics of Balcinrenone When Dosed With a P-gp Inhibitor in Healthy Participants.Who this might be right forHealthy Participants AstraZeneca 14
Testing effectiveness (Phase 2)Study completedNCT01691053What this trial is testingMineralocorticoid Receptor Antagonists in End Stage Renal DiseaseWho this might be right forEnd Stage Renal Disease / Hemodialysis Wuerzburg University Hospital 118
Not applicableUnknownNCT05262660What this trial is testingThe Long-term Effect of SAAE and Medical Treatment for Primary AldosteronismWho this might be right forPrimary Aldosteronism First Affiliated Hospital of Chengdu Medical College 400
Early research (Phase 1)Study completedNCT04798222What this trial is testingStudy to Assess the Bioavailability of Different Formulations of AZD9977 and Dapagliflozin and Influence of Food in Selected Formulations in Healthy VolunteersWho this might be right forHeart Failure AstraZeneca 20
Early research (Phase 1)Study completedNCT01648998What this trial is testingFludrocortisone and Information Processing in Healthy VolunteersWho this might be right forDepression Leiden University Medical Center 40
Not applicableStudy completedNCT03789357What this trial is testingPrevalence of Primary Aldosteronism in Patients With StrokeWho this might be right forPrimary AldosteronismStroke Changi General Hospital 300
Early research (Phase 1)Study completedNCT01103245What this trial is testingAldosterone and the Metabolic SyndromeWho this might be right forMetabolic DiseasesDiabetes MellitusEndocrine System Diseases+1 more Vanderbilt University Medical Center 69
Post-approval studies (Phase 4)Study completedNCT03476616What this trial is testingAntihypertensive Pharmacological Therapy With Mineralocorticoid Receptor Antagonists in Obese Hypertensive PatientsWho this might be right forHypertensionObesity Hippocration General Hospital 198
Post-approval studies (Phase 4)Not Yet RecruitingNCT07523867What this trial is testingSpironolactone Alternate Dosing vs Finerenone in Elevated Potassium - K Safety StudyWho this might be right forHeart FailureDiabetic Kidney DiseaseHyperkalemia Hospital de Messejana Dr. Carlos Alberto Studart Gomes 60