Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Neoadjuvant Therapy in Rectal Cancer”

412 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 412 results

Large-scale testing (Phase 3)UnknownNCT03415763
What this trial is testing

Adjuvant Chemotherapy in Patients With Clinical Stage III Rectal Cancer Undergoing Neoadjuvant Chemoradiotherapy

Who this might be right for
Rectal Neoplasms
LI XIN-XIANG 764
Testing effectiveness (Phase 2)Looking for participantsNCT07789210
What this trial is testing

A Single-Arm, Phase II, Multicenter Clinical Study of Neoadjuvant Encorafenib Plus Cetuximab N01 and mFOLFOX6 in Patients With Locally Advanced BRAF V600E-Mutant Colorectal Cancer With or Without Resectable Metastases

Who this might be right for
Colorectal CancerBRAF V600E Mutation PositiveEncorafenib+1 more
Zhejiang University 25
Testing effectiveness (Phase 2)Study completedNCT00081289
What this trial is testing

Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy in Treating Patients Who Are Undergoing Surgical Resection for Locally Advanced Rectal Cancer

Who this might be right for
Colorectal Cancer
Radiation Therapy Oncology Group 146
Testing effectiveness (Phase 2)UnknownNCT06304987
What this trial is testing

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Beijing Friendship Hospital 50
Testing effectiveness (Phase 2)Looking for participantsNCT05254327
What this trial is testing

Trial of the Efficacy and Safety of Short and Long Course Radiation Therapy With/Without BMX-001

Who this might be right for
Rectal Cancer
University of Nebraska 118
Large-scale testing (Phase 3)Active Not RecruitingNCT04928807
What this trial is testing

Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy and Camrelizumab in Locally Advanced Rectal Cancer (UNION)

Who this might be right for
Rectal Cancer
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 231
Early research (Phase 1)UnknownNCT04906044
What this trial is testing

Total Neoadjuvant Treatment Plus PD-1 in Mid-Low Locally Advanced Rectal Cancer

Who this might be right for
TislelizumabLocally Advanced Rectal CancerTotal Neoadjuvant Treatment+1 more
The First Hospital of Jilin University 46
Testing effectiveness (Phase 2)Ended earlyNCT01871571
What this trial is testing

Bevacizumab, Fluorouracil, Leucovorin Calcium, and Oxaliplatin Before Surgery in Treating Patients With Stage II-III Rectal Cancer

Who this might be right for
Mucinous Adenocarcinoma of the RectumSignet Ring Adenocarcinoma of the RectumStage IIA Rectal Cancer+5 more
University of Southern California 17
Not applicableStudy completedNCT05592873
What this trial is testing

Oncological Impact of Lateral Nodes in Rectal Cancer

Who this might be right for
Colorectal Adenocarcinoma
Niguarda Hospital 317
Testing effectiveness (Phase 2)UnknownNCT01237665
What this trial is testing

IXO (Irinotecan, Xeloda, Oxaliplatin) in Rectal Cancer

Who this might be right for
Rectal Cancer
Ottawa Hospital Research Institute 15
Not applicableLooking for participantsNCT05523245
What this trial is testing

Predicting the Efficacy of Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer Using an AI Platform Based on Multi-parametric MRI

Who this might be right for
Rectal Cancer
Sixth Affiliated Hospital, Sun Yat-sen University 1,700
Testing effectiveness (Phase 2)Looking for participantsNCT05748145
What this trial is testing

Metronidazole as Preoperative Therapy in CRC / FusoMetro-001

Who this might be right for
Colorectal Cancer
Oncology Institute of Southern Switzerland 40
Testing effectiveness (Phase 2)Looking for participantsNCT06923345
What this trial is testing

Modified Long-Course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for MSS/pMMR High-risk Mid/Low LARC (MODIFI-RC-I)

Who this might be right for
Rectal CancerNeoadjuvant TherapiesImmune Checkpoint Therapy+1 more
Sixth Affiliated Hospital, Sun Yat-sen University 80
Testing effectiveness (Phase 2)UnknownNCT02161822
What this trial is testing

Capecitabine Plus Simvastatin in Locally Advanced Rectal Cancer Patients

Who this might be right for
Adenocarcinoma of Rectum
Samsung Medical Center 60
Not applicableWithdrawnNCT00835055
What this trial is testing

Expression of Molecular Markers Before and After Neo-adjuvant Chemoradiotherapy in Rectal Cancer

Who this might be right for
Rectal Cancer
St. Claraspital AG
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07509424
What this trial is testing

Neoadjuvant Short-course Radiotherapy Followed by a Combination of Disitamab Vedotin, Sintilimab, and Capecitabine in Locally Advanced HER2-expressing Rectal Cance

Who this might be right for
Rectal Cancer
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 29
Not applicableWithdrawnNCT03749083
What this trial is testing

The Role of Circulating Tumor DNA in Predicting the Likelihood of Organ Preservation After Clinical Complete Response to Neoadjuvant Therapy for Rectal Cancer

Who this might be right for
Gastrointestinal Malignancies
Massachusetts General Hospital
Not applicableEnded earlyNCT02614157
What this trial is testing

Lateral Lymph Node Dissection After Neoadjuvant Chemo-radiation in Advanced Low Rectal Cancer

Who this might be right for
Rectal Cancer
West China Hospital 51
Not applicableStudy completedNCT05534841
What this trial is testing

Assessment of Complete Response MRI Criterion After Neoadjuvant Therapy in Locally Advanced Rectal Cancer

Who this might be right for
Rectal Neoplasms
Centre Hospitalier Universitaire de Nīmes 99
Testing effectiveness (Phase 2)Study completedNCT00909987
What this trial is testing

Study of Neoadjuvant CT With Selective Radiotherapy in Patients With Intermediate-Risk Cancer Rectum

Who this might be right for
Rectum Cancer
Grupo Espanol Multidisciplinario del Cancer Digestivo 46
Next Page