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Results for “Nevoid Basal Cell Carcinoma Syndrome”

17 trials

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Showing 17 of 17 results

Large-scale testing (Phase 3)WithdrawnNCT03070691
What this trial is testing

Efficacy, Safety and Tolerability of Topically Applied LDE225 Cream (Hedgehog Pathway Inhibitor) in Adult Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

Who this might be right for
Basal Cell Carcinoma
Novartis Pharmaceuticals
Large-scale testing (Phase 3)Ended earlyNCT00049959
What this trial is testing

Two Studies to Determine if Verteporfin PDT is Effective & Safe in Treating Multiple Basal Cell Carcinoma of the Skin.

Who this might be right for
Basal Cell CarcinomaNevoid Basal Cell Carcinoma SyndromeGorlin Syndrome
QLT Inc.
Large-scale testing (Phase 3)Ended earlyNCT04308395
What this trial is testing

Extension Study of Patidegib Topical Gel, 2% in Subjects With Gorlin Syndrome (Basal Cell Nevus Syndrome)

Who this might be right for
Basal Cell Nevus Syndrome
Sol-Gel Technologies, Ltd. 108
Testing effectiveness (Phase 2)Study completedNCT00961896
What this trial is testing

A Trial to Evaluate the Safety, Local Tolerability, Pharmacokinetics and Pharmacodynamics of LDE225 on Skin Basal Cell Carcinomas in Gorlin Syndrome Patients

Who this might be right for
Treatment for Basal Cell Carcinomas (BCCs) in Gorlin Syndrome Patients
Novartis Pharmaceuticals 18
Testing effectiveness (Phase 2)Study completedNCT02017964
What this trial is testing

Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic Medulloblastoma

Who this might be right for
Desmoplastic/Nodular MedulloblastomaMedulloblastomaMedulloblastoma With Extensive Nodularity+1 more
Children's Oncology Group 26
Testing effectiveness (Phase 2)Study completedNCT01350115
What this trial is testing

Efficacy, Safety and Pharmacokinetics of Oral LDE225 in Treatment of Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

Who this might be right for
Basal Cell CarcinomaGorlin SyndromeNevoid Basal Cell Carcinoma Syndrome
Novartis Pharmaceuticals 10
Not applicableStudy completedNCT00025012
What this trial is testing

Isotretinoin in Preventing Skin Cancer

Who this might be right for
Melanoma (Skin)Non-melanomatous Skin Cancer
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Testing effectiveness (Phase 2)Study completedNCT00489086
What this trial is testing

Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer and Basal Cell Nevus Syndrome on the Face

Who this might be right for
Neoplastic Syndrome
UCSF Benioff Children's Hospital Oakland 36
Early research (Phase 1)Study completedNCT00670189
What this trial is testing

BMS-833923 (XL139) in Subjects With Advanced or Metastatic Cancer

Who this might be right for
Hedgehog PathwaySmoothenedBasal Cell Carcinoma (BCC)+1 more
Bristol-Myers Squibb 53
Large-scale testing (Phase 3)Study completedNCT03703310
What this trial is testing

Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas (BCCs) in Subjects With Basal Cell Nevus Syndrome (Gorlin Syndrome)

Who this might be right for
Basal Cell Nevus Syndrome
Sol-Gel Technologies, Ltd. 174
Early research (Phase 1)Study completedNCT00433485
What this trial is testing

Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy Participants

Who this might be right for
Neoplastic SyndromeNon-melanomatous Skin Cancer
Yale University 16
Testing effectiveness (Phase 2)Study completedNCT02828111
What this trial is testing

Clinical Trial of Patidegib Gel 2%, 4%, and Vehicle Applied Once or Twice Daily to Decrease the GLI1 Biomarker in Sporadic Nodular Basal Cell Carcinomas

Who this might be right for
Basal Cell Carcinomas
PellePharm, Inc. 36
Testing effectiveness (Phase 2)Study completedNCT02762084
What this trial is testing

Trial of Patidegib Gel 2%, 4%, and Vehicle to Decrease the Number of Surgically Eligible Basal Cell Carcinomas in Gorlin Syndrome Patients

Who this might be right for
Basal Cell Nevus Syndrome
PellePharm, Inc. 17
Testing effectiveness (Phase 2)Study completedNCT04893486
What this trial is testing

CODY: A Study Evaluating The Safety And Efficacy Of QTORIN 3.9% Sirolimus Topical Gel For The Prevention Of Basal Cell Carcinomas (BCCs) In Patients With Gorlin Syndrome

Who this might be right for
BCCs in Gorlin Syndrome Patients
Palvella Therapeutics, Inc. 73
Testing effectiveness (Phase 2)Study completedNCT00783965
What this trial is testing

Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer and Basal Cell Nevus Syndrome on the Chest and Back

Who this might be right for
Skin Carcinoma
UCSF Benioff Children's Hospital Oakland 34
Not applicableLooking for participantsNCT03050268
What this trial is testing

Familial Investigations of Childhood Cancer Predisposition

Who this might be right for
Acute LeukemiaAdenomatous PolyposisAdrenocortical Carcinoma+43 more
St. Jude Children's Research Hospital 1,500
Not applicableUnknownNCT05898347
What this trial is testing

Nevoid Basal Cell Carcinomas in Gorlin Syndrome

Who this might be right for
Basal Cell CarcinomaGorlin Syndrome
Oslo University Hospital 10