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Results for “Newly Diagnosed Philadelphia Chromosome Negative”

81 trials

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Showing 20 of 81 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT02143414
What this trial is testing

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1+2 more
National Cancer Institute (NCI) 53
Testing effectiveness (Phase 2)Active Not RecruitingNCT01920737
What this trial is testing

A Novel "Pediatric-Inspired" Regimen With Reduced Myelosuppressive Drugs for Adults (Aged 18-60) With Newly Diagnosed Ph Negative Acute Lymphoblastic Leukemia

Who this might be right for
Leukemia
Memorial Sloan Kettering Cancer Center 39
Large-scale testing (Phase 3)Study completedNCT01511289
What this trial is testing

Radotinib Versus Imatinib in Newly Diagnosed Philadelphia Chromosome and Chronic Myeloid Leukemia Chronic Phase Patients

Who this might be right for
LeukemiaLeukemia, MyeloidLeukemia, Myelogenous, Chronic, BCR-ABL Positive+3 more
Il-Yang Pharm. Co., Ltd. 242
Large-scale testing (Phase 3)UnknownNCT00002869
What this trial is testing

Interferon Alfa in Treating Patients With Newly Diagnosed Chronic Myelogenous Leukemia

Who this might be right for
Leukemia
Medical Research Council 800
Testing effectiveness (Phase 2)Study completedNCT05557110
What this trial is testing

Reduced-dose Chemotherapy Followed by Blinatumomab in Induction Therapy of Newly Diagnosed Non-elderly Ph-B-ALL

Who this might be right for
B Acute Lymphoblastic Leukemia
Chen Suning 35
Large-scale testing (Phase 3)Study completedNCT00471497
What this trial is testing

Imatinib Versus Nilotinib in Adult Patients With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP)

Who this might be right for
Myelogenous Leukemia, Chronic
Novartis Pharmaceuticals 846
Post-approval studies (Phase 4)UnknownNCT02690922
What this trial is testing

Low-dose Chemotherapy Combine With Tyrosine Kinase Inhibitor to Treat ph+ Acute Lymphoblastic Leukemia Patients

Who this might be right for
ph+ Acute Lymphoblastic Leukemia
Tongji Hospital 40
Testing effectiveness (Phase 2)Looking for participantsNCT06250959
What this trial is testing

RDC-Blinatumomab Versus hyperCVAD for Ph-negative B-ALL.

Who this might be right for
ALL, AdultPhiladelphia-Negative ALL
Chen Suning 124
Testing effectiveness (Phase 2)Looking for participantsNCT06738368
What this trial is testing

Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) With or Without Rituximab Plus Recombinant Erwinia Asparaginase (JZP458) for the Treatment of Newly Diagnosed Ph Negative B-Acute Lymphoblastic Leukemia or T Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome NegativeT Acute Lymphoblastic Leukemia
University of Washington 30
Post-approval studies (Phase 4)Ended earlyNCT05071482
What this trial is testing

Flumatinib Versus Imatinib Combined With Chemotherapy for de Novo Ph+ ALL

Who this might be right for
Acute Leukemia
Institute of Hematology & Blood Diseases Hospital, China 39
Testing effectiveness (Phase 2)UnknownNCT06578546
What this trial is testing

Chemotherapy-free Regimen of Venetoclax, Azacitidine Plus Orebatinib (VAO Regimen) for Newly Diagnosed ph+ALL

Who this might be right for
Ph-Positive Acute Lymphoblastic Leukemia
The First Affiliated Hospital of Soochow University 30
Early research (Phase 1)Study completedNCT01132573
What this trial is testing

Entinostat and Clofarabine in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Poor-Risk Acute Lymphoblastic Leukemia or Bilineage/Biphenotypic Leukemia

Who this might be right for
Acute Leukemias of Ambiguous LineagePhiladelphia Chromosome Negative Adult Precursor Acute Lymphoblastic LeukemiaRecurrent Adult Acute Lymphoblastic Leukemia+1 more
National Cancer Institute (NCI) 27
Testing effectiveness (Phase 2)Active Not RecruitingNCT04258943
What this trial is testing

Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia

Who this might be right for
Philadelphia Chromosome Positive CMLAccelerated Phase Chronic Myelogenous LeukemiaBlastic Phase Chronic Myelogenous Leukemia+1 more
Children's Oncology Group 60
Large-scale testing (Phase 3)Not Yet RecruitingNCT07223190
What this trial is testing

A Study Evaluating Subcutaneous Versus Intravenous Blinatumomab in Newly Diagnosed Adults With B-cell Precursor Acute Lymphoblastic Leukaemia

Who this might be right for
Philadelphia Chromosome Negative B-cell Precursor Acute Lymphoblastic Leukemia
Amgen 560
Large-scale testing (Phase 3)Active Not RecruitingNCT03007147
What this trial is testing

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic LeukemiaMixed Phenotype Acute Leukemia+1 more
Children's Oncology Group 352
Testing effectiveness (Phase 2)Study completedNCT03480438
What this trial is testing

Treatment of Older Patients With B-precursor ALL With Sequential Dose Reduced Chemotherapy and Blinatumomab

Who this might be right for
B-Precursor ALL
Goethe University 52
Large-scale testing (Phase 3)Study completedNCT00006343
What this trial is testing

STI571 Compared With Interferon Alfa Plus Cytarabine in Treating Patients With Newly Diagnosed Chronic Myelogenous Leukemia

Who this might be right for
Leukemia
Novartis
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06930105
What this trial is testing

Impact of Low-intensity Chemotherapy Combined With Short-course Blinatumomab on Allo-HSCT in Adults With Ph- B-ALL

Who this might be right for
Acute Lymphoid Leukemia (ALL)
Xianmin Song, MD 45
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06773936
What this trial is testing

Adding Asciminib to Usual Treatment for Adults With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia

Who this might be right for
Philadelphia Chromosome Positive Acute Lymphoblastic LeukemiaCD19+ Acute Leukemia
SWOG Cancer Research Network 55
Large-scale testing (Phase 3)Ended earlyNCT01891643
What this trial is testing

PH III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Previously Untreated Multiple Myeloma (ELO 1 Substudy)

Who this might be right for
Newly Diagnosed, Previously Untreated Multiple Myeloma
Bristol-Myers Squibb 23
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