Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “OPSCC”

27 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 27 results

Not applicableLooking for participantsNCT07133958
What this trial is testing

A Bidirectional Observational Clinical Study of NAIC in the Treatment of Tumor Regression Patterns in LA-OSCC and LA-OPSCC

Who this might be right for
Oral Squamous Cell Carcinoma (OSCC)Oropharyngeal Squamous Cell Carcinoma (SCC)
Zhujiang Hospital 35
Testing effectiveness (Phase 2)Looking for participantsNCT05419089
What this trial is testing

The Sinai Robotic Surgery Trial in HPV-related Oropharyngeal Squamous Cell Carcinoma (SIRS 2.0 Trial)

Who this might be right for
HPV-positive Oropharyngeal Squamous Cell Carcinoma
Icahn School of Medicine at Mount Sinai 83
Not applicableLooking for participantsNCT06174428
What this trial is testing

Validity of Viome's Oral/throat Cancer Test

Who this might be right for
Oral and Throat CancerOropharyngeal Squamous Cell CarcinomaOral Squamous Cell Carcinoma
Viome 1,000
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06759155
What this trial is testing

Phase II Clinical Trial of De-Intensified Therapy in Human Papilloma Virus (HPV) Associated Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
OPSCCOropharyngeal Squamous Cell Carcinoma (SCC)HPV Associated Cancers
University of Vermont Medical Center 20
Not applicableUnknownNCT05065086
What this trial is testing

Single Modality Trans Oral Robotic Surgery for Primary Oropharyngeal Cancer: Exploring the Impact of Surgical Margins on Local Disease Recurrence

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Royal Marsden NHS Foundation Trust 500
Testing effectiveness (Phase 2)Ended earlyNCT04106362
What this trial is testing

Radiation Therapy and Cisplatin With or Without Cetuximab in Treating Patients With HPV Positive, KRAS-Variant Stage III-IV Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8KRAS Protein Variant+2 more
Jonsson Comprehensive Cancer Center 1
Not applicableEnded earlyNCT01891695
What this trial is testing

OPSCC N0 Nodal Control With Reduced IMRT

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma (OPSCCA)HPV (Human Papillomavirus)-Associated
Paul W. Read, MD 1
Testing effectiveness (Phase 2)Ended earlyNCT03258008
What this trial is testing

Utomilumab and ISA101b Vaccination in Patients With HPV-16-Positive Incurable Oropharyngeal Cancer

Who this might be right for
Malignant Neoplasms of Ill-defined Secondary and Unspecified SitesMalignant Neoplasms of Lip Oral Cavity and PharynxOropharyngeal Cancer
M.D. Anderson Cancer Center 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT03799445
What this trial is testing

Ipilimumab, Nivolumab, and Radiation Therapy in Treating Patients With HPV Positive Advanced Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma+8 more
M.D. Anderson Cancer Center
Not applicableUnknownNCT02663583
What this trial is testing

Intensity-Modulated Proton Therapy (IMPT) or TransOral Robotic Surgery (TORS) for the Treatment of Low-Risk Oropharynx Squamous Cell

Who this might be right for
Cancer of the MouthOropharynx Squamous Cell Carcinoma
M.D. Anderson Cancer Center 44
Not applicableLooking for participantsNCT04564989
What this trial is testing

Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC

Who this might be right for
Oropharyngeal Squamous Cell CarcinomaCarcinoma, Squamous CellHead and Neck Squamous Cell Carcinoma+1 more
UNC Lineberger Comprehensive Cancer Center 220
Testing effectiveness (Phase 2)Temporarily pausedNCT06254911
What this trial is testing

Pre-operative Atezolizumab in Patients With Resectable, Human Papillomavirus Related Oropharyngeal Carcinoma

Who this might be right for
Oropharynx Cancer, Stage I
Emory University 20
Large-scale testing (Phase 3)Active Not RecruitingNCT03811015
What this trial is testing

Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

Who this might be right for
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
National Cancer Institute (NCI) 636
Not applicableStudy completedNCT06771674
What this trial is testing

Real-world Study of First Line Pembrolizumab- or Nivolumab-treated HPV-positive Recurrent/Metastatic Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma
Hookipa Biotech GmbH 662
Large-scale testing (Phase 3)UnknownNCT01874171
What this trial is testing

Determination of Cetuximab Versus Cisplatin Early and Late Toxicity Events in HPV+ OPSCC

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma
University of Warwick 334
Not applicableStudy completedNCT03759730
What this trial is testing

Role of Microbiome as a Biomarkers in Locoregionally-Advanced Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Locoregionally-advanced Oropharyngeal Squamous Cell Carcinoma
University Health Network, Toronto 26
Not applicableActive Not RecruitingNCT06592716
What this trial is testing

Can Recurrence of Cancer in the Oropharynx be Detected by Blood Samples?

Who this might be right for
Oropharynx CancerOropharynx Cancer, MetastaticOropharynx Cancer, Recurrent+2 more
Rigshospitalet, Denmark 200
Testing effectiveness (Phase 2)Study completedNCT03715946
What this trial is testing

Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer

Who this might be right for
Carcinoma, Squamous Cell of Head and NeckOropharynx Squamous Cell Carcinoma
Robert L. Ferris, MD, PhD 40
Early research (Phase 1)Study completedNCT04572100
What this trial is testing

Pilot Study of Chemotherapy for HPV-Associated Oropharyngeal Cancer

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma
University of Chicago 50
Testing effectiveness (Phase 2)Ended earlyNCT04916002
What this trial is testing

A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancer

Who this might be right for
Merkel Cell CarcinomaCutaneous Squamous Cell CarcinomaBasal Cell Carcinoma+3 more
Regeneron Pharmaceuticals 77
Load More Results
37