Early research (Phase 1)Study completedNCT07543276What this trial is testingPharmacokinetic (PK) Evaluation of Nalmefene FormulationsWho this might be right forOpioid Overdose Knoa Pharma LLC 13
Large-scale testing (Phase 3)Ended earlyNCT03818399What this trial is testingVirginia Opioid Overdose Treatment InitiatVEWho this might be right forOpioid Use Disorder Virginia Commonwealth University 19
Early research (Phase 1)Study completedNCT06005402What this trial is testingSafety, Tolerability, and Pharmacokinetics of CSX-1004Who this might be right forOpioid OverdoseOpioid Use Disorder Cessation Therapeutics, Inc. 32
Not applicableStudy completedNCT02535494What this trial is testingRisks and Benefits of Naloxone PrescribingWho this might be right forOpioid Overdose New York State Psychiatric Institute 405
Not applicableStudy completedNCT02669901What this trial is testingNaloxone Auto-injector as a Universal Precaution for Patients With Opioid Use DisorderWho this might be right forOpiate Antagonist OverdoseOpioid-Related Disorders University of New Mexico 395
Early research (Phase 1)Study completedNCT05363501What this trial is testingPharmacokinetic Evaluation of a New Naloxone Nasal Swab, Naloxone Nasal Spray, and Intramuscular Naloxone Injection in Healthy VolunteersWho this might be right forOpioid Overdose Pocket Naloxone Corp 76
Post-approval studies (Phase 4)Study completedNCT03908437What this trial is testingRapid Initiation of Drug Treatment EngagementWho this might be right forOpioid-use DisorderOverdose University of Pennsylvania 104
Post-approval studies (Phase 4)WithdrawnNCT05876572What this trial is testingBlood Naloxone Levels Following Intradermal Injection in HumansWho this might be right forOpioid Overdose Johns Hopkins University
Early research (Phase 1)Study completedNCT04713709What this trial is testingA Single-Dose, Bioequivalence Study of FMXIN001 4 mg Microspheres PowderWho this might be right forOpioid Overdose Nasus Pharma 46
Post-approval studies (Phase 4)Looking for participantsNCT04811014What this trial is testingYoung Houston Emergency Opioid Engagement SystemWho this might be right forOpioid-use DisorderOpioid DependenceOpioid Overdose+2 more The University of Texas Health Science Center, Houston 250
Not applicableStudy completedNCT03821649What this trial is testingSOONER Feasibility Study ProtocolWho this might be right forOverdose Unity Health Toronto 90
Not applicableEnrolling By InvitationNCT06523985What this trial is testingThe Feasibility of Using the PulsePoint to Facilitate Overdose Education and Naloxone DistributionWho this might be right forCarrying Naloxone/Narcan on Their Person or in Their VehicleBeing Trained to Respond to an Opioid Overdose Indiana University 5,000
Not applicableUnknownNCT04815590What this trial is testingExtended-release Injectable Buprenorphine for Individuals at High Risk of OverdoseWho this might be right forOpioid-Use DisorderOpioid Overdose BC Centre on Substance Use 40
Not applicableStudy completedNCT02120612What this trial is testingIncreasing Patient Knowledge of the Signs of Opioid Overdose and Naloxone in a Suburban Treatment ProgramWho this might be right forOpioid DependenceOpioid Use Disorder Edward Hospital 100
Not applicableLooking for participantsNCT06806163What this trial is testingMachine-Learning Prediction and Reducing Overdoses With EHR NudgesWho this might be right forOpioid OverdoseOpioid UseOpioid Use Disorder+1 more University of Pittsburgh 1,350
Not applicableStudy completedNCT04253782What this trial is testingSafetyNet Program for Opioid Use Disorder (OUD)Who this might be right forOpioid-Use Disorder (OUD) Yale University 81
Early research (Phase 1)Study completedNCT05219669What this trial is testingPharmacokinetic Evaluation of Intranasal Nalmefene Using Three Dosing RegimensWho this might be right forOpioid Overdose Opiant Pharmaceuticals Inc 24
Not applicableUnknownNCT03845699What this trial is testingDevelopment of an Algorithm That Predicts Hypoventilation Due to an Opioid OverdoseWho this might be right forDrug OverdoseOpioid-Related Disorders RTM Vital Signs, LLC 20
Not applicableStudy completedNCT06949605What this trial is testingQuantitative Xylazine Measurement in EDWho this might be right forOpioid OverdoseSubstance Use Disorders Icahn School of Medicine at Mount Sinai 75
Early research (Phase 1)UnknownNCT02733822What this trial is testingBuccal Versus Injectable Naloxone: a Phase I Healthy Volunteer StudyWho this might be right forDrug OverdoseOpioid-Related Disorders King's College London 4