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Results for “Optic Atrophy, Autosomal Dominant”

13 trials

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Showing 13 of 13 results

Not applicableEnded earlyNCT06140329
What this trial is testing

Natural History of Autosomal Dominant Optic Atrophy (ADOA), Caused by OPA1 Mutation

Who this might be right for
Autosomal Dominant Optic AtrophyOptic Atrophy, Autosomal DominantOptic Atrophies, Hereditary+1 more
PYC Therapeutics 1
Not applicableStudy completedNCT04518059
What this trial is testing

Misfolded Proteins in the Skin of People With Parkinson's Disease and Other Parkinsonism

Who this might be right for
Parkinson DiseaseParkinsonismDementia With Lewy Bodies+3 more
University Hospitals Cleveland Medical Center 184
Not applicableStudy completedNCT00804102
What this trial is testing

Transcorneal Electrical Stimulation Therapy for Retinal Disease

Who this might be right for
Retinitis PigmentosaMacula OffPrimary Open Angle Glaucoma+8 more
Okuvision GmbH 80
Not applicableLooking for participantsNCT03011541
What this trial is testing

Stem Cell Ophthalmology Treatment Study II

Who this might be right for
Retinal DiseaseAge-Related Macular DegenerationRetinitis Pigmentosa+15 more
MD Stem Cells 500
Testing effectiveness (Phase 2)Looking for participantsNCT06970106
What this trial is testing

Safety of Single and Repeat Dose of PYC-001 Eye Injections in People With Autosomal Dominant Optic Atrophy (Myrtle)

Who this might be right for
OPA1 Gene MutationAutosomal Dominant Optic AtrophyHereditary Optic Atrophies+1 more
PYC Therapeutics 24
Not applicableEnded earlyNCT04020198
What this trial is testing

A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies

Who this might be right for
Parkinson DiseaseMultiple System AtrophyRapid Eye Movement Sleep Behavior Disorder+1 more
Stony Brook University 8
Early research (Phase 1)Active Not RecruitingNCT06461286
What this trial is testing

SAD of IVT PYC-001 in OPA1 Mutation-Associated Autosomal Dominant Optic Atrophy (Sundew)

Who this might be right for
OPA1 Gene MutationAutosomal Dominant Optic AtrophyHereditary Optic Atrophies+1 more
PYC Therapeutics 18
Not applicableUnknownNCT01522638
What this trial is testing

Advanced Characterization of Autosomal Dominant Optic Atrophy

Who this might be right for
Optic Atrophy, Autosomal Dominant
Glostrup University Hospital, Copenhagen 50
Not applicableUnknownNCT02114242
What this trial is testing

Biomarkers in Parkinsonian Syndromes

Who this might be right for
Parkinsonian SyndromesParkinson's DiseaseMultiple System Atrophy+1 more
University Hospital, Bordeaux 100
Not applicableLooking for participantsNCT07729982
What this trial is testing

A Longitudinal Natural History Study of OPA1-Associated Autosomal-Dominant Optic Atrophy

Who this might be right for
OPA1 Gene MutationOptic Atrophy, Autosomal Dominant
Ludwig-Maximilians - University of Munich 50
Large-scale testing (Phase 3)Active Not RecruitingNCT06007391
What this trial is testing

Tolerance and Efficacy Nicotinamide (Vitamin B3) in Dominant Optic Atrophy OPA1

Who this might be right for
Nicotinamide Adverse Reaction
University Hospital, Angers 25
Not applicableUnknownNCT01249053
What this trial is testing

Expression of Optic Atrophy Type 1 (OPA1) Protein in Lung Adenocarcinoma

Who this might be right for
Lung Adenocarcinoma
China Medical University Hospital 100
Not applicableLooking for participantsNCT01793168
What this trial is testing

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Who this might be right for
Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more
Sanford Health 20,000