Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Optic Atrophy, Hereditary, Leber”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT05293626
What this trial is testing

Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND4 Mutations

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Neurophth Therapeutics Inc 12
Testing effectiveness (Phase 2)Ended earlyNCT01389817
What this trial is testing

Near-infrared Light-emitting Diode (NIR-LED) Therapy for Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Medical College of Wisconsin 4
Not applicableNot Yet RecruitingNCT07075887
What this trial is testing

Optic Nerve Head Evaluation Through Multimodal Blood Flow Analysis: a Prospective Observational, Multi-center Study

Who this might be right for
Neuro-OphthalmologyOptic NeuropathiesOptic Atrophy, Hereditary, Leber+3 more
Barboni 70
Early research (Phase 1)Study completedNCT02161380
What this trial is testing

Safety Study of an Adeno-associated Virus Vector for Gene Therapy of Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber's Hereditary Optic Neuropathy
Byron Lam 28
Not applicableLooking for participantsNCT03011541
What this trial is testing

Stem Cell Ophthalmology Treatment Study II

Who this might be right for
Retinal DiseaseAge-Related Macular DegenerationRetinitis Pigmentosa+15 more
MD Stem Cells 500
Not applicableEnded earlyNCT02982499
What this trial is testing

Biomechanics of Optic Neuropathy

Who this might be right for
Optic Neuropathy
University of Miami 10
Testing effectiveness (Phase 2)UnknownNCT02176733
What this trial is testing

Trial of Cyclosporine in the Acute Phase of Leber Hereditary Optic Neuropathy

Who this might be right for
Leber Hereditary Optic Neuropathy
University Hospital, Angers 12
Testing effectiveness (Phase 2)Ended earlyNCT05820152
What this trial is testing

Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND1 Mutations

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Neurophth Therapeutics Inc 11
Not applicableNo Longer AvailableNCT04381091
What this trial is testing

Expanded Access Program for Idebenone in Patients With Leber's Hereditary Optic Neuropathy Who Completed the LEROS Study

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals
Testing effectiveness (Phase 2)Study completedNCT00747487
What this trial is testing

Study to Assess Efficacy,Safety and Tolerability of Idebenone in the Treatment of Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals 85
Large-scale testing (Phase 3)Looking for participantsNCT04912843
What this trial is testing

Gene Therapy Clinical Trial for the Treatment Of Leber's HereDitary Optic Neuropathy

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Wuhan Neurophth Biotechnology Limited Company 102
Large-scale testing (Phase 3)Looking for participantsNCT06891443
What this trial is testing

Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)

Who this might be right for
Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+7 more
Laboratoires Thea 32
Testing effectiveness (Phase 2)Looking for participantsNCT07303296
What this trial is testing

Efficacy and Safety Study of Bilateral IVT Injection of GS010 at Two Dose Levels in LHON Patients

Who this might be right for
Leber Hereditary Optic Disease
GenSight Biologics 14
Testing effectiveness (Phase 2)Study completedNCT02064569
What this trial is testing

Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients

Who this might be right for
Leber Hereditary Optic Neuropathy
GenSight Biologics 19
Not applicableActive Not RecruitingNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Not applicableStudy completedNCT01421381
What this trial is testing

RHODOS Follow-up Single-visit Study

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals 60
Large-scale testing (Phase 3)Study completedNCT00528151
What this trial is testing

A Randomized, Double-blind, Placebo-controlled Trial of Curcumin in Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Optic Atrophy, Hereditary, Leber
Mahidol University 70
Large-scale testing (Phase 3)Study completedNCT03293524
What this trial is testing

Efficacy & Safety Study of Bilateral IVT Injection of GS010 in LHON Subjects Due to the ND4 Mutation for up to 1 Year

Who this might be right for
Leber Hereditary Optic Neuropathy
GenSight Biologics 98
Large-scale testing (Phase 3)Active Not RecruitingNCT03913143
What this trial is testing

Evaluate Efficacy, Safety, Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in LCA10 (ILLUMINATE)

Who this might be right for
Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+7 more
ProQR Therapeutics 36
Not applicableLooking for participantsNCT01694940
What this trial is testing

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

Who this might be right for
Mitochondrial DisordersMitochondrial Genetic DisordersMitochondrial Diseases+2 more
Columbia University 1,000
Next Page