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Results for “Optic Nerve Atrophy”

144 trials

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Showing 20 of 144 results

Not applicableEnded earlyNCT06140329
What this trial is testing

Natural History of Autosomal Dominant Optic Atrophy (ADOA), Caused by OPA1 Mutation

Who this might be right for
Autosomal Dominant Optic AtrophyOptic Atrophy, Autosomal DominantOptic Atrophies, Hereditary+1 more
PYC Therapeutics 1
Not applicableStudy completedNCT03076671
What this trial is testing

More Than a Movement Disorder: Applying Palliative Care to Parkinson's Disease

Who this might be right for
Parkinson DiseaseParkinsonismLewy Body Disease+8 more
University of Colorado, Denver 783
Large-scale testing (Phase 3)Study completedNCT03293524
What this trial is testing

Efficacy & Safety Study of Bilateral IVT Injection of GS010 in LHON Subjects Due to the ND4 Mutation for up to 1 Year

Who this might be right for
Leber Hereditary Optic Neuropathy
GenSight Biologics 98
Not applicableActive Not RecruitingNCT05913687
What this trial is testing

Automated Imaging Differentiation of Parkinsonism

Who this might be right for
Parkinson DiseaseMultiple System Atrophy, Parkinson VariantProgressive Supranuclear Palsy
University of Florida 315
Not applicableLooking for participantsNCT02194816
What this trial is testing

Modifiable Variables in Parkinsonism (MVP)

Who this might be right for
Parkinson's DiseaseParkinsonismMSA - Multiple System Atrophy+6 more
Bastyr University 2,000
Not applicableStudy completedNCT04518059
What this trial is testing

Misfolded Proteins in the Skin of People With Parkinson's Disease and Other Parkinsonism

Who this might be right for
Parkinson DiseaseParkinsonismDementia With Lewy Bodies+3 more
University Hospitals Cleveland Medical Center 184
Testing effectiveness (Phase 2)Study completedNCT02064569
What this trial is testing

Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients

Who this might be right for
Leber Hereditary Optic Neuropathy
GenSight Biologics 19
Not applicableStudy completedNCT00804102
What this trial is testing

Transcorneal Electrical Stimulation Therapy for Retinal Disease

Who this might be right for
Retinitis PigmentosaMacula OffPrimary Open Angle Glaucoma+8 more
Okuvision GmbH 80
Not applicableStudy completedNCT03552484
What this trial is testing

In-Home Care for Patients With PSP and Related Disorders

Who this might be right for
Progressive Supranuclear PalsyDementia With Lewy BodiesMultiple System Atrophy+2 more
Rush University Medical Center 56
Not applicableLooking for participantsNCT03011541
What this trial is testing

Stem Cell Ophthalmology Treatment Study II

Who this might be right for
Retinal DiseaseAge-Related Macular DegenerationRetinitis Pigmentosa+15 more
MD Stem Cells 500
Early research (Phase 1)Study completedNCT01064505
What this trial is testing

Safety Study of a Single IVT Injection of QPI-1007 in Chronic Optic Nerve Atrophy and Recent Onset NAION Patients

Who this might be right for
Optic AtrophyNon-arteritic Anterior Ischemic Optic Neuropathy
Quark Pharmaceuticals 48
Not applicableNot Yet RecruitingNCT07336966
What this trial is testing

Does Recessive Optic Atrophy Due to WFS1 Exist?

Who this might be right for
Wolfram Syndrome 1Optic Atrophies, Hereditary
Hôpital Necker-Enfants Malades 45
Testing effectiveness (Phase 2)Ended earlyNCT03913130
What this trial is testing

Extension Study to Study PQ-110-001 (NCT03140969)

Who this might be right for
Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+7 more
Laboratoires Thea 9
Testing effectiveness (Phase 2)Looking for participantsNCT06162013
What this trial is testing

The NADAPT Study: a Randomized Double-blind Trial of NAD Replenishment Therapy for Atypical Parkinsonism

Who this might be right for
Progressive Supranuclear PalsyMultiple System AtrophyCorticobasal Syndrome
Haukeland University Hospital 330
Not applicableUnknownNCT01920867
What this trial is testing

Stem Cell Ophthalmology Treatment Study

Who this might be right for
Retinal DiseaseMacular DegenerationHereditary Retinal Dystrophy+2 more
MD Stem Cells 300
Large-scale testing (Phase 3)Active Not RecruitingNCT07406854
What this trial is testing

A Phase 3, Multicenter, Randomized, Double-Masked, Sham-Controlled Clinical Trial for Leber's Hereditary Optic Neuropathy (LHON) Associated With ND4 Mutation

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Wuhan Neurophth Biotechnology Limited Company 95
Not applicableStudy completedNCT03452956
What this trial is testing

Cognitive Impairement In Frontotemporal Dementia

Who this might be right for
Frontotemporal DegenerationProgressive Supranuclear PalsyMultiple System Atrophy
University of Pennsylvania 997
Post-approval studies (Phase 4)Study completedNCT03924414
What this trial is testing

Trial of Parkinson's And Zoledronic Acid

Who this might be right for
Parkinson DiseaseOsteoporosisParkinsonism+6 more
California Pacific Medical Center Research Institute 2,721
Testing effectiveness (Phase 2)Looking for participantsNCT06970106
What this trial is testing

Safety of Single and Repeat Dose of PYC-001 Eye Injections in People With Autosomal Dominant Optic Atrophy (Myrtle)

Who this might be right for
OPA1 Gene MutationAutosomal Dominant Optic AtrophyHereditary Optic Atrophies+1 more
PYC Therapeutics 24
Not applicableStudy completedNCT04909398
What this trial is testing

Pupil Dynamics and Color Vision for the Detection of Eye Diseases

Who this might be right for
Retinitis PigmentosaLeber's Hereditary Optic NeuropathyStargardt Disease
Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts 60
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