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Results for “Oropharyngeal Squamous Cell Carcinoma (OPSCC)”

29 trials

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Showing 20 of 29 results

Testing effectiveness (Phase 2)Looking for participantsNCT05419089
What this trial is testing

The Sinai Robotic Surgery Trial in HPV-related Oropharyngeal Squamous Cell Carcinoma (SIRS 2.0 Trial)

Who this might be right for
HPV-positive Oropharyngeal Squamous Cell Carcinoma
Icahn School of Medicine at Mount Sinai 83
Testing effectiveness (Phase 2)Study completedNCT03715946
What this trial is testing

Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer

Who this might be right for
Carcinoma, Squamous Cell of Head and NeckOropharynx Squamous Cell Carcinoma
Robert L. Ferris, MD, PhD 40
Testing effectiveness (Phase 2)Looking for participantsNCT07513389
What this trial is testing

Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION)

Who this might be right for
Squamous Cell CarcinomaHuman Papilloma Virus (HPV)Oropharyngeal Squamous Cell Carcinoma (OPSCC)
Medical University of South Carolina 36
Testing effectiveness (Phase 2)Temporarily pausedNCT06254911
What this trial is testing

Pre-operative Atezolizumab in Patients With Resectable, Human Papillomavirus Related Oropharyngeal Carcinoma

Who this might be right for
Oropharynx Cancer, Stage I
Emory University 20
Testing effectiveness (Phase 2)Ended earlyNCT03799445
What this trial is testing

Ipilimumab, Nivolumab, and Radiation Therapy in Treating Patients With HPV Positive Advanced Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma+8 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06759155
What this trial is testing

Phase II Clinical Trial of De-Intensified Therapy in Human Papilloma Virus (HPV) Associated Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
OPSCCOropharyngeal Squamous Cell Carcinoma (SCC)HPV Associated Cancers
University of Vermont Medical Center 20
Early research (Phase 1)Study completedNCT01721525
What this trial is testing

Induction Chemotherapy With Afatinib, Ribavirin, and Weekly Carboplatin/Paclitaxel for Stage IVA/IVB HPV Associated Oropharynx Squamous Cell Cancer (OPSCC)

Who this might be right for
Head and Neck CancerSquamous Cell Cancer
Memorial Sloan Kettering Cancer Center 10
Testing effectiveness (Phase 2)Ended earlyNCT04106362
What this trial is testing

Radiation Therapy and Cisplatin With or Without Cetuximab in Treating Patients With HPV Positive, KRAS-Variant Stage III-IV Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8KRAS Protein Variant+2 more
Jonsson Comprehensive Cancer Center 1
Not applicableEnded earlyNCT02045186
What this trial is testing

Monitoring of Oral Human Papillomavirus Infection (HPV) in HPV-positive Oropharyngeal Squamous Cell Carcinoma (OPSCC)

Who this might be right for
Carcinoma, Squamous CellHead and Neck NeoplasmsOropharyngeal Neoplasms
UNC Lineberger Comprehensive Cancer Center 1
Large-scale testing (Phase 3)UnknownNCT01874171
What this trial is testing

Determination of Cetuximab Versus Cisplatin Early and Late Toxicity Events in HPV+ OPSCC

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma
University of Warwick 334
Early research (Phase 1)Looking for participantsNCT07565740
What this trial is testing

Intranasal WSK-IM05 Vaccine Plus Tislelizumab as Neoadjuvant Therapy for HPV+ OPSCC

Who this might be right for
HPV-positive Oropharyngeal Squamous Cell Carcinoma
West China Hospital 9
Testing effectiveness (Phase 2)Ended earlyNCT03258008
What this trial is testing

Utomilumab and ISA101b Vaccination in Patients With HPV-16-Positive Incurable Oropharyngeal Cancer

Who this might be right for
Malignant Neoplasms of Ill-defined Secondary and Unspecified SitesMalignant Neoplasms of Lip Oral Cavity and PharynxOropharyngeal Cancer
M.D. Anderson Cancer Center 3
Not applicableLooking for participantsNCT04564989
What this trial is testing

Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC

Who this might be right for
Oropharyngeal Squamous Cell CarcinomaCarcinoma, Squamous CellHead and Neck Squamous Cell Carcinoma+1 more
UNC Lineberger Comprehensive Cancer Center 220
Not applicableLooking for participantsNCT07133958
What this trial is testing

A Bidirectional Observational Clinical Study of NAIC in the Treatment of Tumor Regression Patterns in LA-OSCC and LA-OPSCC

Who this might be right for
Oral Squamous Cell Carcinoma (OSCC)Oropharyngeal Squamous Cell Carcinoma (SCC)
Zhujiang Hospital 35
Not applicableUnknownNCT05065086
What this trial is testing

Single Modality Trans Oral Robotic Surgery for Primary Oropharyngeal Cancer: Exploring the Impact of Surgical Margins on Local Disease Recurrence

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Royal Marsden NHS Foundation Trust 500
Early research (Phase 1)Study completedNCT04572100
What this trial is testing

Pilot Study of Chemotherapy for HPV-Associated Oropharyngeal Cancer

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma
University of Chicago 50
Not applicableActive Not RecruitingNCT06592716
What this trial is testing

Can Recurrence of Cancer in the Oropharynx be Detected by Blood Samples?

Who this might be right for
Oropharynx CancerOropharynx Cancer, MetastaticOropharynx Cancer, Recurrent+2 more
Rigshospitalet, Denmark 200
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07552558
What this trial is testing

Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)

Who this might be right for
Head and Neck Squamous Cell CarcinomaHPV-Negative Squamous Cell Carcinoma
Washington University School of Medicine 45
Testing effectiveness (Phase 2)Ended earlyNCT04916002
What this trial is testing

A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancer

Who this might be right for
Merkel Cell CarcinomaCutaneous Squamous Cell CarcinomaBasal Cell Carcinoma+3 more
Regeneron Pharmaceuticals 77
Not applicableLooking for participantsNCT06174428
What this trial is testing

Validity of Viome's Oral/throat Cancer Test

Who this might be right for
Oral and Throat CancerOropharyngeal Squamous Cell CarcinomaOral Squamous Cell Carcinoma
Viome 1,000
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