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Results for “Oropharyngeal Squamous Cell Carcinoma (OPSCC)”

32 trials

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Showing 20 of 32 results

Early research (Phase 1)Study completedNCT04572100
What this trial is testing

Pilot Study of Chemotherapy for HPV-Associated Oropharyngeal Cancer

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma
University of Chicago 50
Not applicableLooking for participantsNCT04564989
What this trial is testing

Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC

Who this might be right for
Oropharyngeal Squamous Cell CarcinomaCarcinoma, Squamous CellHead and Neck Squamous Cell Carcinoma+1 more
UNC Lineberger Comprehensive Cancer Center 220
Testing effectiveness (Phase 2)Study completedNCT03715946
What this trial is testing

Adjuvant De-Escalated Radiation + Adjuvant Nivolumab for Intermediate-High Risk P16+ Oropharynx Cancer

Who this might be right for
Carcinoma, Squamous Cell of Head and NeckOropharynx Squamous Cell Carcinoma
Robert L. Ferris, MD, PhD 40
Early research (Phase 1)Study completedNCT01721525
What this trial is testing

Induction Chemotherapy With Afatinib, Ribavirin, and Weekly Carboplatin/Paclitaxel for Stage IVA/IVB HPV Associated Oropharynx Squamous Cell Cancer (OPSCC)

Who this might be right for
Head and Neck CancerSquamous Cell Cancer
Memorial Sloan Kettering Cancer Center 10
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06759155
What this trial is testing

Phase II Clinical Trial of De-Intensified Therapy in Human Papilloma Virus (HPV) Associated Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
OPSCCOropharyngeal Squamous Cell Carcinoma (SCC)HPV Associated Cancers
University of Vermont Medical Center 20
Testing effectiveness (Phase 2)Ended earlyNCT04916002
What this trial is testing

A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancer

Who this might be right for
Merkel Cell CarcinomaCutaneous Squamous Cell CarcinomaBasal Cell Carcinoma+3 more
Regeneron Pharmaceuticals 77
Testing effectiveness (Phase 2)Ended earlyNCT03258008
What this trial is testing

Utomilumab and ISA101b Vaccination in Patients With HPV-16-Positive Incurable Oropharyngeal Cancer

Who this might be right for
Malignant Neoplasms of Ill-defined Secondary and Unspecified SitesMalignant Neoplasms of Lip Oral Cavity and PharynxOropharyngeal Cancer
M.D. Anderson Cancer Center 3
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07418034
What this trial is testing

A Single Arm Phase II Trial in p16-positive Oropharynx Cancer of Selective Dose De-escalation of nodAl VolumEs at Minimal Risk and Primary Site Disease (SAVED)

Who this might be right for
Head and Neck CancerHead and Neck Squamous Cell CancerHead and Neck Squamous Cell Carcinoma+11 more
University of Maryland, Baltimore 132
Not applicableStudy completedNCT03759730
What this trial is testing

Role of Microbiome as a Biomarkers in Locoregionally-Advanced Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Locoregionally-advanced Oropharyngeal Squamous Cell Carcinoma
University Health Network, Toronto 26
Testing effectiveness (Phase 2)Ended earlyNCT03799445
What this trial is testing

Ipilimumab, Nivolumab, and Radiation Therapy in Treating Patients With HPV Positive Advanced Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma+8 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07812467
What this trial is testing

Rimegepant-Sensitized Neoadjuvant Chemoimmunotherapy for Oral or Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Oral Squamous Cell Carcinoma (OSCC)Oropharyngeal Squamous Cell Carcinoma (OPSCC)
Shanghai Zhongshan Hospital 220
Not applicableEnded earlyNCT02045186
What this trial is testing

Monitoring of Oral Human Papillomavirus Infection (HPV) in HPV-positive Oropharyngeal Squamous Cell Carcinoma (OPSCC)

Who this might be right for
Carcinoma, Squamous CellHead and Neck NeoplasmsOropharyngeal Neoplasms
UNC Lineberger Comprehensive Cancer Center 1
Testing effectiveness (Phase 2)Looking for participantsNCT07513389
What this trial is testing

Omission of Postoperative Radiation in HPV-Associated Oropharyngeal Cancer Using ctHPVDNA Surveillance (OPERATION)

Who this might be right for
Squamous Cell CarcinomaHuman Papilloma Virus (HPV)Oropharyngeal Squamous Cell Carcinoma (OPSCC)
Medical University of South Carolina 36
Large-scale testing (Phase 3)UnknownNCT01874171
What this trial is testing

Determination of Cetuximab Versus Cisplatin Early and Late Toxicity Events in HPV+ OPSCC

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma
University of Warwick 334
Not applicableLooking for participantsNCT07133958
What this trial is testing

A Bidirectional Observational Clinical Study of NAIC in the Treatment of Tumor Regression Patterns in LA-OSCC and LA-OPSCC

Who this might be right for
Oral Squamous Cell Carcinoma (OSCC)Oropharyngeal Squamous Cell Carcinoma (SCC)
Zhujiang Hospital 35
Not applicableUnknownNCT05065086
What this trial is testing

Single Modality Trans Oral Robotic Surgery for Primary Oropharyngeal Cancer: Exploring the Impact of Surgical Margins on Local Disease Recurrence

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Royal Marsden NHS Foundation Trust 500
Testing effectiveness (Phase 2)Looking for participantsNCT06254911
What this trial is testing

Pre-operative Atezolizumab in Patients With Resectable, Human Papillomavirus Related Oropharyngeal Carcinoma

Who this might be right for
Oropharynx Cancer, Stage I
Emory University 20
Not applicableUnknownNCT06138483
What this trial is testing

A New Mutational and Epigenetic Signature to Predict Early OPSCC Relapse

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma
Centro di Riferimento Oncologico - Aviano 267
Not applicableEnded earlyNCT01891695
What this trial is testing

OPSCC N0 Nodal Control With Reduced IMRT

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma (OPSCCA)HPV (Human Papillomavirus)-Associated
Paul W. Read, MD 1
Not applicableLooking for participantsNCT07686575
What this trial is testing

Objective Response Rate of Ivonescimab With Chemotherapy in Locally Advanced Resectable Oral and Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
HNSCCOSCCOPSCC+1 more
Zhujiang Hospital 20
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