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Results for “PARP”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Active Not RecruitingNCT01874353
What this trial is testing

Olaparib Treatment in BRCA Mutated Ovarian Cancer Patients After Complete or Partial Response to Platinum Chemotherapy

Who this might be right for
Platinum SensitiveBRCA MutatedRelapsed Ovarian Cancer+1 more
AstraZeneca 327
Testing effectiveness (Phase 2)Ended earlyNCT03442556
What this trial is testing

Docetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair Deficiency

Who this might be right for
ATM Gene MutationBRCA1 Gene MutationBRCA2 Gene Mutation+7 more
University of Washington 18
Early research (Phase 1)Study completedNCT02759666
What this trial is testing

A Phase I Trial of SHR3162 in Subjects With Advanced Solid Tumors

Who this might be right for
NeoplasmSolid Tumors
Atridia Pty Ltd. 30
Testing effectiveness (Phase 2)Ended earlyNCT05501548
What this trial is testing

Phase II Study of PARP Inhibitor Olaparib and IV Ascorbate in Castration Resistant Prostate Cancer

Who this might be right for
Prostate CancerCastration-resistant Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 4
Testing effectiveness (Phase 2)Active Not RecruitingNCT04753879
What this trial is testing

Multi-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cancer.

Who this might be right for
Metastatic Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 38
Early research (Phase 1)Study completedNCT00516438
What this trial is testing

Study to Assess the Safety and Tolerability of a PARP Inhibitor in Combination With Topotecan

Who this might be right for
Malignant Solid Tumors
AstraZeneca 48
Testing effectiveness (Phase 2)Study completedNCT03639935
What this trial is testing

Rucaparib in Combination With Nivolumab in Patients With Advanced or Metastatic Biliary Tract Cancer Following Platinum Therapy

Who this might be right for
Biliary Tract Cancer
University of Michigan Rogel Cancer Center 32
Early research (Phase 1)Study completedNCT00516802
What this trial is testing

Assess the Safety and Pharmacokinetics of an Inhibitor of PARP in Combination With Dacarbazine

Who this might be right for
Melanoma Neoplasms
AstraZeneca 40
Early research (Phase 1)Study completedNCT02482311
What this trial is testing

Safety, Tolerance, PK, and Anti-tumour Activity of AZD1775 Monotherapy in Patients With Advanced Solid Tumours

Who this might be right for
Ovarian Cancer, TNBC, SCLC, Other Solid Tumours
AstraZeneca 92
Testing effectiveness (Phase 2)Ended earlyNCT02576444
What this trial is testing

OLAParib COmbinations

Who this might be right for
Cancer
Joseph Paul Eder 67
Testing effectiveness (Phase 2)Looking for participantsNCT04858334
What this trial is testing

APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

Who this might be right for
Pancreatic Acinar Cell CarcinomaPancreatic Adenosquamous CarcinomaPancreatic Squamous Cell Carcinoma+4 more
National Cancer Institute (NCI) 152
Early research (Phase 1)Ended earlyNCT01127178
What this trial is testing

Study of Poly (ADP-Ribose) Polymerase (PARP) Inhibitor E7016 in Combination With Temozolomide in Subjects With Advanced Solid Tumors

Who this might be right for
Solid Tumors
Eisai Inc. 12
Early research (Phase 1)Ended earlyNCT06509906
What this trial is testing

M9466 in Combination With Topoisomerase 1 Inhibitors-based Regimens in Advanced Solid Tumors and Colorectal Cancer (DDRiver 511)

Who this might be right for
Advanced Solid Tumor
EMD Serono Research & Development Institute, Inc. 3
Not applicableNot Yet RecruitingNCT06838429
What this trial is testing

PARPi and Ovarian Cancer Survival

Who this might be right for
Epithelial Ovarian Cancer, Fallopian Tube or PeritoneumPARP Inhibitor
Shanghai Gynecologic Oncology Group 6,000
Testing effectiveness (Phase 2)Study completedNCT01051596
What this trial is testing

ABT-888 in Combination With Temozolomide for Colorectal Cancer

Who this might be right for
Colorectal Cancer
Georgetown University 75
Testing effectiveness (Phase 2)UnknownNCT05475184
What this trial is testing

Evaluate the Efficacy and Safety of JPI-547 in Platinum-resistant, Advanced/Relapsed Ovarian Cancer Subjects Previously Treated With a PARP Inhibitor

Who this might be right for
Ovarian Cancer
Onconic Therapeutics Inc. 58
Early research (Phase 1)Study completedNCT02483104
What this trial is testing

Veliparib in Combination With Carboplatin And Weekly Paclitaxel in Japanese Subjects With Ovarian Cancer

Who this might be right for
Ovarian Cancer
AbbVie 9
Testing effectiveness (Phase 2)Active Not RecruitingNCT04701307
What this trial is testing

Niraparib and Dostarlimab for the Treatment of Small Cell Lung Cancer and Other High-Grade Neuroendocrine Carcinomas

Who this might be right for
Lung Small Cell CarcinomaNeuroendocrine CarcinomaStage III Lung Cancer AJCC v8+3 more
M.D. Anderson Cancer Center 48
Not applicableLooking for participantsNCT06775470
What this trial is testing

Impact of Different BRCA1/2 Gene Variants on Response to Therapy and Prognosis of Ovarian Cancer

Who this might be right for
Ovarian Cancer
IRCCS Azienda Ospedaliero-Universitaria di Bologna 300
Early research (Phase 1)Study completedNCT02033551
What this trial is testing

A Study Evaluating Veliparib as a Single Agent or in Combination With Chemotherapy in Subjects With Solid Tumors

Who this might be right for
Breast CancerOvarian CancerColon Cancer+3 more
AbbVie 47
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