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Results for “PCSK9”

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Showing 20 of 0 results

Very early researchUnknownNCT06140095
What this trial is testing

Studies to Gain Insight How the Drugs PCSK9-inhibitors and Statins Affect Cholesterol and Bile Acid Metabolism

Who this might be right for
Acute Metabolic Effects of Evolocumab and Atorvastatin
Region Stockholm 8
Not applicableStudy completedNCT04319081
What this trial is testing

Study to Evaluate Changes in Cognitive Function in Patients Treated With PCSK9 Inhibitors

Who this might be right for
Cognitive FunctionHypercholesterolemiaQuality of Life
Jose Seijas Amigo 180
Early research (Phase 1)Study completedNCT05934292
What this trial is testing

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Renal Impairment Study (MK-0616-020)

Who this might be right for
Hypercholesterolaemia
Merck Sharp & Dohme LLC 33
Testing effectiveness (Phase 2)Study completedNCT01375764
What this trial is testing

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects

Who this might be right for
Hyperlipidemia
Amgen 160
Not applicableLooking for participantsNCT06863545
What this trial is testing

Further Lipid-Lowering With PCSK9 Inhibitors for Cardiovascular Outcomes in High-Risk Coronary Plaques Assessed by CT Angiography

Who this might be right for
Coronary Artery DiseaseCT AngiographyPCSK9+1 more
Second Affiliated Hospital, Zhejiang University, School of Medicine 3,596
Post-approval studies (Phase 4)Study completedNCT03626831
What this trial is testing

Effect of Evolocumab on Vascular Function

Who this might be right for
Atherosclerotic Cardiovascular Disease
University of Erlangen-Nürnberg Medical School 105
Post-approval studies (Phase 4)Study completedNCT03096288
What this trial is testing

Impact of Evolocumab on the Effects of Clopidogrel in Patients With High On-Treatment Platelet Reactivity

Who this might be right for
Atherosclerotic Cardiovascular Disease
University of Florida 259
Not applicableLooking for participantsNCT05397405
What this trial is testing

Improving Blood Lipid Management in Symptomatic Intracranial Atherosclerotic Stenosis on Clinical Outcome

Who this might be right for
Intracranial Artery Stenosis
Nanjing First Hospital, Nanjing Medical University 180
Testing effectiveness (Phase 2)Active Not RecruitingNCT06933251
What this trial is testing

PCSK9 Inhibitor and PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy for pMMR/MSS Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer (LARC)
Guangdong Provincial People's Hospital 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07391722
What this trial is testing

DNV001 Injection in Patients With Hypercholesterolemia

Who this might be right for
Primary Hypercholesterolemia
Hangzhou Dinovate Biotech Co., Ltd 120
Not applicableStudy completedNCT05184530
What this trial is testing

In-hospital Initiation of PCSK9 Inhibitor in Patients With Acute Myocardial Infarction

Who this might be right for
Coronary Disease
First Affiliated Hospital Xi'an Jiaotong University 7,556
Testing effectiveness (Phase 2)UnknownNCT04338165
What this trial is testing

Impact of PCSK9 Inhibitors on Coronary Microvascular Dysfunction in Patients With Atherosclerotic Cardiovascular Disease Proved by Myocardial Ischemia and Needing Coronarography

Who this might be right for
Atherosclerotic Cardiovascular Disease
University Hospital, Grenoble 66
Not applicableUnknownNCT04730648
What this trial is testing

Acute Myocardial Infarction and Unstable Angina Patients With PCSK9 Inhibitor Usage Study

Who this might be right for
Lipid MetabolismCardiovascular Diseases
Shenzhen People's Hospital 100
Not applicableNot Yet RecruitingNCT06791031
What this trial is testing

PCSK9 inhibitoRs for Early Passivation of coRonary athEroSclerotic plaqueS in Acute Coronary Syndromes (REPRESS)

Who this might be right for
Coronary Artery Disease
West China Hospital 212
Post-approval studies (Phase 4)UnknownNCT05976893
What this trial is testing

Study on the Composite Endpoint Event of PCSK9 Inhibitor in Patients With Very High Risk of ASCVD and Cancer

Who this might be right for
ASCVDAtherosclerotic Cardiovascular DiseaseProprotein Convertase Subtilisin/Kexin Type 9 Inhibitor+1 more
Xiang Xie 620
Very early researchActive Not RecruitingNCT04862260
What this trial is testing

Cholesterol Disruption in Combination With the Standard of Care in Patients With Advanced Pancreatic Adenocarcinoma

Who this might be right for
Pancreatic Ductal AdenocarcinomaPancreatic CancerPancreas Cancer+1 more
CHU de Quebec-Universite Laval 3
Large-scale testing (Phase 3)Study completedNCT02867813
What this trial is testing

Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk Open-label Extension

Who this might be right for
Dyslipidemia
Amgen 5,035
Large-scale testing (Phase 3)Looking for participantsNCT04968509
What this trial is testing

Effect of PCSK9 Inhibitors on Calcific Aortic Valve Stenosis

Who this might be right for
Aortic Stenosis
Beijing Anzhen Hospital 160
Post-approval studies (Phase 4)Looking for participantsNCT04731155
What this trial is testing

Impact of Early PCSK9 Inhibitor on Heart After Acute Myocardium Infarction

Who this might be right for
Early PCSK9 Inhibitor on Ventricular Remodling
Shanghai Tong Ren Hospital 20
Large-scale testing (Phase 3)Study completedNCT01588496
What this trial is testing

Trial Evaluating PCSK9 Antibody in Subjects With LDL Receptor Abnormalities

Who this might be right for
Homozygous Familial Hypercholesterolemia
Amgen 58
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