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Results for “PD-1/CTLA-4”

197 trials

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Showing 20 of 197 results

Testing effectiveness (Phase 2)WithdrawnNCT04149275
What this trial is testing

Cabozantinib Plus Nivolumab and Ipilimumab in Women With Recurrent Gynecologic Carcinosarcoma

Who this might be right for
Carcinosarcoma of OvaryCarcinosarcoma of UterusCarcinosarcoma of Vagina
University of Alabama at Birmingham
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06509971
What this trial is testing

QL1706 (an Anti-PD-1/CTLA-4 Combined Antibody) Combined With Albumin-bound Paclitaxel and Bevacizumab in the Treatment of Platinum-resistant Recurrent Ovarian Cancer

Who this might be right for
Platinum-resistant Recurrent Ovarian Cancer
West China Second University Hospital 39
Not applicableLooking for participantsNCT05332925
What this trial is testing

Using Ex Vivo Tumoroids To Predict Immunotherapy Response In NSCLC

Who this might be right for
Lung CancerNSCLCNSCLC Stage IV
Jun Zhang, MD, PhD 25
Testing effectiveness (Phase 2)Active Not RecruitingNCT05014776
What this trial is testing

Study of CRS-207, Pembrolizumab, Ipilimumab, and Tadalafil in Metastatic Pancreatic Cancer

Who this might be right for
Pancreatic Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 17
Early research (Phase 1)Study completedNCT04572152
What this trial is testing

AK119 (Anti-CD73) in Combination With AK104 in Subjects With Advanced Solid Tumors

Who this might be right for
Advanced or Metastatic Solid Tumors
Akeso 23
Testing effectiveness (Phase 2)Active Not RecruitingNCT05529316
What this trial is testing

Botensilimab (AGEN1181) for the Treatment of Advanced Melanoma

Who this might be right for
Advanced Melanoma
Agenus Inc. 150
Testing effectiveness (Phase 2)Active Not RecruitingNCT04556253
What this trial is testing

AK104 in Locally Advanced MSI-H/dMMR Gastric Carcinoma and Colorectal Cancer

Who this might be right for
MSI-H/dMMR Gastric Carcinoma and Colorectal Cancer
Peking University 47
Testing effectiveness (Phase 2)UnknownNCT04544644
What this trial is testing

Combination Therapy in NSCLC

Who this might be right for
Non-small Cell Lung Cancer
Chinese PLA General Hospital 30
Testing effectiveness (Phase 2)Looking for participantsNCT06494995
What this trial is testing

AK104 and Low-dose Radiation in Recurrent/Metastatic HNSCC After Failure of First-line Systemic Therapy

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Fudan University 52
Not applicableNot Yet RecruitingNCT06155422
What this trial is testing

A Prospective Real-world Study of Cadonilimab in Patients With Recurrent or Metastatic Cervical Cancer

Who this might be right for
Recurrent or Metastatic Cervical Cancer
Gang Chen (101199) 670
Testing effectiveness (Phase 2)WithdrawnNCT04007588
What this trial is testing

A Phase II Trial of Neoadjuvant Treatment With PD-1 Inhibition (Nivolumab) With or Without IDO Inhibition (BMS-986205) and With or Without CTLA-4 Inhibition (Ipilimumab) in Resectable Stage III or IV Melanoma

Who this might be right for
Melanoma Stage IIIMelanoma Stage IV
Dana-Farber Cancer Institute
Testing effectiveness (Phase 2)Looking for participantsNCT07315854
What this trial is testing

Iparomlimab and Tuvonralimab (QL1706) Combined With Chemotherapy for Previously Untreated Advanced or Metastatic Gastric or Gastroesophageal Junction Cancer

Who this might be right for
Gastric Cancer (GC)Gastroesophageal Junction CancerAdvanced Gastric Cancer+1 more
Beijing Friendship Hospital 32
Testing effectiveness (Phase 2)Study completedNCT02694822
What this trial is testing

AGEN1884, an Anti-CTLA-4 Human Monoclonal Antibody in Participants With Advanced or Refractory Cancer and Who Have Progressed With PD-1/PD-L1 Inhibitor as Their Most Recent Therapy

Who this might be right for
Advanced Solid CancersAdvanced Solid Cancers Refractory to PD-1 and PD-L1 Therapies
Agenus Inc. 89
Testing effectiveness (Phase 2)Active Not RecruitingNCT02834013
What this trial is testing

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Who this might be right for
Acinar Cell CarcinomaAdenoid Cystic CarcinomaAdrenal Cortical Carcinoma+91 more
National Cancer Institute (NCI) 818
Testing effectiveness (Phase 2)UnknownNCT05990231
What this trial is testing

Cadonilimab/Anlotinib in Locally Advanced or Relapsed/Metastatic ESCC Patients After Failure of PD-1 Combined With Platinum-containing Chemotherapy

Who this might be right for
Esophageal Squamous Cell Carcinoma
Second Affiliated Hospital, School of Medicine, Zhejiang University 35
Early research (Phase 1)Ended earlyNCT01940809
What this trial is testing

Ipilimumab With or Without Dabrafenib, Trametinib, and/or Nivolumab in Treating Patients With Melanoma That Is Metastatic or Cannot Be Removed by Surgery

Who this might be right for
BRAF V600E Mutation PresentBRAF V600K Mutation PresentMetastatic Melanoma+5 more
National Cancer Institute (NCI) 15
Testing effectiveness (Phase 2)UnknownNCT05915481
What this trial is testing

Stereotactic Body Radiotherapy Combined With Cadonilimab for Advanced Refractory Malignant Solid Tumors

Who this might be right for
Advanced Solid TumorStereotactic Body RadiotherapyImmune Checkpoint Inhibitor+2 more
Peking University Third Hospital 60
Large-scale testing (Phase 3)Looking for participantsNCT03952065
What this trial is testing

IT or IA Infusion of PD1/PDL1/CTLA4 Inhibitors Versus IV for Immunotherapy of Head/Neck Cancers (HNC)

Who this might be right for
Head/Neck Neoplasm
Second Affiliated Hospital of Guangzhou Medical University 200
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06196775
What this trial is testing

Cadonilimab Combined With AK112 as Second-line Therapy in Patients With Advanced Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Harbin Medical University 36
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07131501
What this trial is testing

A Single-Arm, Multicenter, Exploratory Clinical Study of TACE Combined With Iparomlimab and Tuvonralimab Injection (QL1706) and Lenvatinib for Perioperative Treatment of Resectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular CarcinomaImmunotherapyPreoperative+2 more
The First Affiliated Hospital with Nanjing Medical University 48
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