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Results for “PD-1/CTLA-4”

202 trials

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Showing 20 of 202 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07515469
What this trial is testing

A Prospective, Single-Arm, Exploratory Study of the Safety and Efficacy of Neoadjuvant Treatment With QL1706, an Anti-PD-1/Anti-CTLA-4 Bispecific Antibody, in Resectable Stage IB and IIA Hepatocellular Carcinoma With High Recurrence Risk

Who this might be right for
HCC - Hepatocellular CarcinomaIparomlimab and Tuvonralimab InjectionNeoadjuvant Immunotherapy
Tianjin Medical University Cancer Institute and Hospital 30
Not applicableStudy completedNCT03549546
What this trial is testing

Expression of the Inhibitory Receptors on Lymphocytes T Cells After Lung Cancer Surgery.

Who this might be right for
Lung CancerSurgery
Centre Hospitalier Universitaire de Saint Etienne 31
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05732662
What this trial is testing

SBRT Combined With AK104 to Treatment Relapsed or Metastatic ESCC

Who this might be right for
Recurrent or Metastatic Esophageal Squamous Cell Carcinoma
The First People's Hospital of Changzhou 25
Testing effectiveness (Phase 2)UnknownNCT03356782
What this trial is testing

Safety and Efficacy Evaluation of 4th Generation Safety-engineered CAR T Cells Targeting Sarcomas

Who this might be right for
SarcomaOsteoid SarcomaEwing Sarcoma
Shenzhen Geno-Immune Medical Institute 20
Testing effectiveness (Phase 2)Looking for participantsNCT06762080
What this trial is testing

Intrathecal Combination of Programmed Death-1 (PD-1)/Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4) Bispecific Antibody and Pemetrexed for Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis
Guangzhou Medical University 36
Early research (Phase 1)Not Yet RecruitingNCT06934616
What this trial is testing

A Phase I, First-in-Human Study of GB268 (PD-1/CTLA-4/VEGF Trispecific Antibody) in Advanced Solid Tumors

Who this might be right for
Solid Tumor Cancer
Genor Biopharma Co., Ltd. 330
Early research (Phase 1)Study completedNCT03293784
What this trial is testing

TNF-Inhibitor as Immune Checkpoint Inhibitor for Advanced MELanoma

Who this might be right for
Melanoma
Institut Claudius Regaud 33
Testing effectiveness (Phase 2)Study completedNCT04225390
What this trial is testing

Preconditioning of Tumor, Tumor Microenvironment and the Immune System to Immunotherapy

Who this might be right for
Immunotherapy
University of Erlangen-Nürnberg Medical School 38
Not applicableStudy completedNCT03387540
What this trial is testing

Evaluation of Reporting of Immune Checkpoint Inhibitor Associated Cardio-vascular Adverse Reactions

Who this might be right for
MyocarditisCardiac Complication
Groupe Hospitalier Pitie-Salpetriere 104
Testing effectiveness (Phase 2)Looking for participantsNCT04080804
What this trial is testing

Study of Safety and Tolerability of Nivolumab Treatment Alone or in Combination With Relatlimab or Ipilimumab in Head and Neck Cancer

Who this might be right for
Head and Neck Squamous Cell Carcinoma (HNSCC)
Dan Zandberg 80
Early research (Phase 1)Looking for participantsNCT05142189
What this trial is testing

Clinical Trial Evaluating the Safety, Tolerability and Preliminary Efficacy of BNT116 Alone and in Combinations in Patients With Advanced Non-small Cell Lung Cancer

Who this might be right for
Non-Small Cell Lung Cancer
BioNTech SE 320
Testing effectiveness (Phase 2)UnknownNCT05235542
What this trial is testing

A Phase Ib/II Study of AK104 and AK117 in Combination With or Without Chemotherapy in Advanced Malignant Tumors

Who this might be right for
Advanced Malignant Tumors
Akeso 130
Large-scale testing (Phase 3)Looking for participantsNCT06794775
What this trial is testing

SWE-NEO: Swedish NeoAdjuvant Trial Comparing Monotherapy to Combined Immunotherapy in Resectable Stage III Melanoma

Who this might be right for
Malignant Melanoma Stage III
Hildur Helgadottir 128
Not applicableLooking for participantsNCT07249060
What this trial is testing

Interferon Signature in Anti-CTLA-4 and Anti-PD-1/PD-L1-Treated Cancer Patients Compared With Systemic Autoimmune Disease Patients

Who this might be right for
Immune-Related Adverse EventsLupus Erythematosus, SystemicSjogren Syndrome+3 more
Hospital Universitario Araba 300
Testing effectiveness (Phase 2)Active Not RecruitingNCT05824481
What this trial is testing

Study of Cadonilimab (AK104) Plus Lenvatinib in Patients With Advanced Endometrial Cancer

Who this might be right for
Endometrial CancerEndometrial Adenocarcinoma
Sun Yat-sen University 32
Testing effectiveness (Phase 2)Study completedNCT04740307
What this trial is testing

Safety and Efficacy of Coformulated Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib (E7080/MK-7902) in Advanced Hepatocellular Carcinoma (MK-1308A-004)

Who this might be right for
Advanced Hepatocellular Carcinoma
Merck Sharp & Dohme LLC 116
Testing effectiveness (Phase 2)Looking for participantsNCT03886311
What this trial is testing

Talimogene Laherparepvec, Nivolumab and Trabectedin for Sarcoma

Who this might be right for
Sarcoma
Sarcoma Oncology Research Center, LLC 200
Testing effectiveness (Phase 2)Ended earlyNCT03116529
What this trial is testing

Neoadjuvant Durvalumab and Tremelimumab Plus Radiation for High Risk Soft-Tissue Sarcoma

Who this might be right for
Soft Tissue Sarcoma
University of Maryland, Baltimore 22
Not applicableNot Yet RecruitingNCT07139587
What this trial is testing

The Efficacy and Safety of Iparomlimab/Tuvonralimab (Anti PD-1/CTLA-4) Combined With Albumin-bound Paclitaxel in Second-line Treatment of Patients With Advanced Gastric/Gastroesophageal Junction Adenocarcinoma

Who this might be right for
Gastric CancerGastroesophageal Junction Adenocarcinoma
Qingxia Li 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT02834013
What this trial is testing

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

Who this might be right for
Acinar Cell CarcinomaAdenoid Cystic CarcinomaAdrenal Cortical Carcinoma+91 more
National Cancer Institute (NCI) 818
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