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Results for “PD-1/L1 Inhibitor”

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Showing 18 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT05200559
What this trial is testing

T-regulatory Cell Depletion With E7777 Combined With Pembrolizumab in Recurrent or Metastatic Solid Tumors

Who this might be right for
Epithelial Ovarian Cancer
Alexander B Olawaiye, MD 25
Large-scale testing (Phase 3)Study completedNCT04157985
What this trial is testing

Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsNSCLCBladder Cancer+10 more
Dan Zandberg 161
Testing effectiveness (Phase 2)UnknownNCT05139082
What this trial is testing

Study of CDK4/6 Inhibitor Combined With PD-L1 Monoclonal Antibody in the Treatment of PD-1/PD-L1 Resistance and Abnormal Cell Cycle Digestive System Tumors

Who this might be right for
Digestive System Tumors
Peking University 60
Early research (Phase 1)Looking for participantsNCT05098210
What this trial is testing

Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Locally Advanced Cutaneous Melanoma+22 more
Fred Hutchinson Cancer Center 28
Testing effectiveness (Phase 2)Active Not RecruitingNCT06644768
What this trial is testing

Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations

Who this might be right for
Non-small Cell Lung CancerLung Cancer
Daiichi Sankyo 137
Not applicableLooking for participantsNCT06915389
What this trial is testing

Metabolomic and Lipidomic Analysis Predicts Immunotherapy-related Adverse Events in Gastric Cancer Patients

Who this might be right for
Gastric CancerImmunotherapyAdverse Event+2 more
Qinghai Red Cross Hospital 100
Not applicableLooking for participantsNCT06323382
What this trial is testing

Locoregional Therapy Combined With Bevacizumab and PD1/L1 Inhibitor in Advanced Hepatocellular Carcinoma

Who this might be right for
Advanced Hepatocellular CarcinomaAnti-PD1/PDL1 AntibodyBevacizumab
Sun Yat-sen University 240
Testing effectiveness (Phase 2)Study completedNCT04626479
What this trial is testing

Substudy 03A: A Study of Immune and Targeted Combination Therapies in Participants With First Line (1L) Renal Cell Carcinoma (MK-3475-03A)

Who this might be right for
Carcinoma, Renal Cell
Merck Sharp & Dohme LLC 393
Testing effectiveness (Phase 2)Active Not RecruitingNCT05012371
What this trial is testing

Lenvatinib With Everolimus Versus Cabozantinib for Second-Line or Third-Line Treatment of Metastatic Renal Cell Cancer

Who this might be right for
Advanced Clear Cell Renal Cell CarcinomaMetastatic Clear Cell Renal Cell CarcinomaStage III Renal Cell Cancer AJCC v8+1 more
M.D. Anderson Cancer Center 90
Large-scale testing (Phase 3)Study completedNCT03867084
What this trial is testing

Safety and Efficacy of Pembrolizumab (MK-3475) Versus Placebo as Adjuvant Therapy in Participants With Hepatocellular Carcinoma (HCC) and Complete Radiological Response After Surgical Resection or Local Ablation (MK-3475-937 / KEYNOTE-937)

Who this might be right for
Hepatocellular Carcinoma
Merck Sharp & Dohme LLC 959
Not applicableUnknownNCT04360655
What this trial is testing

Bronchoscopic Microwave Intervention Treatment in Advanced Central NSCLC

Who this might be right for
Effect IncreasedSafety Issues
Shanghai Pulmonary Hospital, Shanghai, China 50
Testing effectiveness (Phase 2)Study completedNCT04767906
What this trial is testing

Cabozantinib Treatment in a Phase II Study for Patients With Hepatocellular Carcinoma (HCC) Refractory to PD-1 Inhibitors

Who this might be right for
Hepatocellular Carcinoma
University of Leipzig 16
Not applicableUnknownNCT05411926
What this trial is testing

Effect of PD-1 /PD-L1 Inhibitor Therapy Before Liver Transplantation on Acute Rejection After Liver Transplantation in Patients With Hepatocellular Carcinoma

Who this might be right for
Hepatocellular CarcinomaAcute Rejection
Beijing Tsinghua Chang Gung Hospital 30
Testing effectiveness (Phase 2)Study completedNCT04626518
What this trial is testing

Substudy 03B: A Study of Immune and Targeted Combination Therapies in Participants With Second Line Plus (2L+) Renal Cell Carcinoma (MK-3475-03B/KEYMAKER-U03)

Who this might be right for
Carcinoma, Renal Cell
Merck Sharp & Dohme LLC 263
Testing effectiveness (Phase 2)Looking for participantsNCT07263386
What this trial is testing

A Phase II, Multicenter, Randomized, Controlled Clinical Study Comparing the Efficacy and Safety of Sintilimab Plus SOX Versus SOX Alone as Adjuvant Therapy for PD-L1-Positive, Stage pN3 Gastric Cancer

Who this might be right for
Gastric Adenocarcinoma
The First Affiliated Hospital with Nanjing Medical University 460
Large-scale testing (Phase 3)Active Not RecruitingNCT03774732
What this trial is testing

PD-1 Inhibitor and Chemotherapy With Concurrent Irradiation at Varied Tumour Sites in Advanced Non-small Cell Lung Cancer

Who this might be right for
Non Small Cell Lung CancerNon Small Cell Lung Cancer MetastaticNon-Small Cell Carcinoma of Lung, TNM Stage 4
UNICANCER 327
Post-approval studies (Phase 4)Not Yet RecruitingNCT06818773
What this trial is testing

Inetetamab Plus Chemotherapy ± PD-1/PD-L1 in HER2+ Advanced Biliary Cancer

Who this might be right for
Metastatic Biliary Tract CancerHER2 Positive
Eastern Hepatobiliary Surgery Hospital 35
Testing effectiveness (Phase 2)UnknownNCT05530200
What this trial is testing

PRaG Regimens Rechallenge for Patients With Resistance to PD1/PD-L1 Inhibitors in Refractory Advanced Solid Tumors.

Who this might be right for
Metastatic Solid Tumor
Second Affiliated Hospital of Soochow University 56