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Results for “PD-L1”

1,562 trials

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Showing 20 of 1,562 results

Large-scale testing (Phase 3)Ended earlyNCT03626545
What this trial is testing

Phase III Study Evaluating Efficacy and Safety of Canakinumab in Combination With Docetaxel in Adult Subjects With Non-small Cell Lung Cancers as a Second or Third Line Therapy

Who this might be right for
Non-Small-Cell Lung
Novartis Pharmaceuticals 245
Early research (Phase 1)Ended earlyNCT02936102
What this trial is testing

FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.

Who this might be right for
Advanced Solid TumorsTriple Negative Breast CancerChordoma and Alveolar Soft Part Sarcoma
Novartis Pharmaceuticals 154
Testing effectiveness (Phase 2)Study completedNCT03403777
What this trial is testing

Avelumab in Refractory Testicular Germ Cell Cancer.

Who this might be right for
Testicular NeoplasmsNeoplasms, Germ Cell and EmbryonalNeoplasms+4 more
National Cancer Institute, Slovakia 8
Testing effectiveness (Phase 2)WithdrawnNCT05539365
What this trial is testing

Dendritic Cell-Based Treatment Plus Immunotherapy for the Treatment of Metastatic or Unresectable Triple Negative Breast Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Triple-Negative Breast Carcinoma+1 more
Roswell Park Cancer Institute
Not applicableNot Yet RecruitingNCT07459192
What this trial is testing

Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors

Who this might be right for
Canser
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 50
Testing effectiveness (Phase 2)Study completedNCT02574598
What this trial is testing

MK-3475 in Combination With Docetaxel vs Docetaxel Alone in Non-Small Cell Lung Cancer Patients

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Instituto Nacional de Cancerologia de Mexico 78
Large-scale testing (Phase 3)Active Not RecruitingNCT03164616
What this trial is testing

Study of Durvalumab + Tremelimumab With Chemotherapy or Durvalumab With Chemotherapy or Chemotherapy Alone for Patients With Lung Cancer (POSEIDON).

Who this might be right for
Non Small Cell Lung Cancer NSCLC
AstraZeneca 1,186
Post-approval studies (Phase 4)Not Yet RecruitingNCT07004335
What this trial is testing

Efficacy and Safety of Iparomlimab and Tuvonralimab Injection in Combination With Bevacizumab After Progression on Anti-PD-(L)1 Therapy in Advanced Melanoma: A Prospective, Single-Arm, Exploratory Clinical Study

Who this might be right for
PD-(L)1CTLA-4Advanced Melanoma+3 more
Hebei Medical University Fourth Hospital 40
Very early researchNot Yet RecruitingNCT06156267
What this trial is testing

Study of Personalized Tumour Vaccines and a PD-L1 Blocker in Patients With Surgically Resected Pancreatic Adenocarcino

Who this might be right for
Pancreatic Cancer
Fudan University 30
Testing effectiveness (Phase 2)Study completedNCT03707587
What this trial is testing

M7824 in People With Recurrent Respiratory Papillomatosis

Who this might be right for
Recurrent Respiratory PapillomatosisRespiratory PapillomatosisLaryngeal Papilloma, Recurrent+1 more
National Cancer Institute (NCI) 9
Testing effectiveness (Phase 2)UnknownNCT03048500
What this trial is testing

Nivolumab and Metformin Hydrochloride in Treating Patients With Stage III-IV Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Who this might be right for
Recurrent Non-Small Cell Lung CarcinomaStage III Non-Small Cell Lung CancerStage IIIA Non-Small Cell Lung Cancer+2 more
Northwestern University 17
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07471165
What this trial is testing

A Prospective, Single-Arm, Phase II Study: PD-L1 Monoclonal Antibody + Chemoradiotherapy as Bridge Therapy to Liver Transplantation for Locally Advanced Perihilar Cholangiocarcinoma (ACHIEVE-LT)

Who this might be right for
Locally Advanced Perihilar Cholangiocarcinoma
The First Affiliated Hospital with Nanjing Medical University 25
Testing effectiveness (Phase 2)WithdrawnNCT03221634
What this trial is testing

Efficacy and Safety Study of Pembrolizumab (MK-3475) in Combination With Daratumumab in Participants With Relapsed Refractory Multiple Myeloma (MK-3475-668/KEYNOTE-668)

Who this might be right for
Multiple Myeloma
Merck Sharp & Dohme LLC
Early research (Phase 1)Study completedNCT02054806
What this trial is testing

Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-028/KEYNOTE-28)

Who this might be right for
Solid Tumor
Merck Sharp & Dohme LLC 477
Testing effectiveness (Phase 2)Study completedNCT03631407
What this trial is testing

Safety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Microsatellite Stable (MSS) Colorectal Cancer (CRC) (MK-7690-046)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 41
Not applicableStudy completedNCT03305133
What this trial is testing

Evaluation of PD-L1 (Programmed Death-Ligand 1) Tumor Expression in Patients With Large-cell Neuroendocrine Carcinoma (NEC)

Who this might be right for
Large Cell Lung CancerNeuroendocrine Carcinoma of Lung (Diagnosis)
Groupe Francais De Pneumo-Cancerologie 86
Large-scale testing (Phase 3)Active Not RecruitingNCT05943795
What this trial is testing

A Clinical Study of SI-B001 Combined With Docetaxel in the Treatment of Non-small Cell Lung Adenocarcinoma and Lung Squamous Cell Carcinoma

Who this might be right for
Non-small Cell Lung AdenocarcinomaSquamous Cell Carcinoma of Lung
Sichuan Baili Pharmaceutical Co., Ltd. 589
Large-scale testing (Phase 3)Active Not RecruitingNCT04246177
What this trial is testing

Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

Who this might be right for
Carcinoma, Hepatocellular
Merck Sharp & Dohme LLC 480
Early research (Phase 1)Study completedNCT03514719
What this trial is testing

PD-L1 Imaging in Non Small Cell Lung Cancer' (PINNACLE)

Who this might be right for
Non Small Cell Lung Cancer
Radboud University Medical Center 24
Early research (Phase 1)Active Not RecruitingNCT06218511
What this trial is testing

A Phase I Trial of IMA970A Plus Montanide in Combination With Durvalumab (Anti-PD-L1)

Who this might be right for
Hepatocellular Carcinoma
National Cancer Institute, Naples 10
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