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Results for “PDL1- Colorectal Carcinoma”

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Showing 20 of 0 results

Early research (Phase 1)Ended earlyNCT03549000
What this trial is testing

A Phase I/Ib Study of NZV930 Alone and in Combination With PDR001 and /or NIR178 in Patients With Advanced Malignancies.

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)Triple Negative Breast Cancer (TNBC)Pancreatic Ductal Adenocarcinoma (PDAC)+4 more
Novartis Pharmaceuticals 127
Early research (Phase 1)Ended earlyNCT04272034
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsMSI-H/dMMR TumorsCutaneous Squamous Cell Carcinoma+15 more
Incyte Corporation 105
Testing effectiveness (Phase 2)Active Not RecruitingNCT05426005
What this trial is testing

Cadonilimab for PD-1/PD-L1 Blockade-refractory, MSI-H/dMMR, Advanced Colorectal Cancer

Who this might be right for
Colorectal Cancer Stage IVMismatch Repair-deficient (dMMR)Microsatellite Instability-high (MSI-H)
Sun Yat-sen University 28
Testing effectiveness (Phase 2)Ended earlyNCT03376659
What this trial is testing

Durvalumab Plus CV301 With Maintenance Chemotherapy in Metastatic Colorectal or Pancreatic Adenocarcinoma

Who this might be right for
Metastatic Colorectal CancerColorectal AdenocarcinomaPancreatic Adenocarcinoma+1 more
Georgetown University 8
Early research (Phase 1)Study completedNCT03517488
What this trial is testing

XmAb®20717 in Subjects With Selected Advanced Solid Tumors

Who this might be right for
MelanomaBreast CarcinomaHepatocellular Carcinoma+25 more
Xencor, Inc. 150
Large-scale testing (Phase 3)Study completedNCT05064059
What this trial is testing

Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Standard of Care in Subjects With Previously Treated Metastatic PD-L1 Positive Colorectal Cancer (MK-4280A-007)

Who this might be right for
Colorectal Cancer
Merck Sharp & Dohme LLC 441
Testing effectiveness (Phase 2)Looking for participantsNCT07079631
What this trial is testing

A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
BioNTech SE 482
Large-scale testing (Phase 3)Active Not RecruitingNCT05239741
What this trial is testing

Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Chinese Participants With Stage IV Colorectal Cancer (MK-3475-C66)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT02983578
What this trial is testing

Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer

Who this might be right for
Advanced Colorectal CarcinomaAdvanced Lung Non-Small Cell CarcinomaLung Non-Small Cell Carcinoma+22 more
M.D. Anderson Cancer Center 39
Testing effectiveness (Phase 2)WithdrawnNCT06557278
What this trial is testing

Combined AlloStim+Anti-PD-L1 in 4L MSS Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Mirror Biologics, Inc.
Testing effectiveness (Phase 2)Study completedNCT03642067
What this trial is testing

Study of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal Cancer

Who this might be right for
Microsatellite Stable (MSS) Colorectal AdenocarcinomasColorectal Adenocarcinoma
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 59
Testing effectiveness (Phase 2)Looking for participantsNCT07281768
What this trial is testing

Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal Cancer

Who this might be right for
Colorectal Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 66
Testing effectiveness (Phase 2)Looking for participantsNCT07284992
What this trial is testing

SCRT VS LCRT Followed by PD-L1 Inhibitor Plus CAPEOX as TNT in Patients With LARC

Who this might be right for
Rectal CancerAdvanced Stage Colorectal CancerRadiotherapy
Shandong Provincial Hospital 208
Early research (Phase 1)Study completedNCT02754856
What this trial is testing

Tremelimumab and Durvalumab in Treating Patients With Colorectal Cancer With Liver Metastases That Can Be Removed by Surgery

Who this might be right for
Metastatic Carcinoma in the LiverResectable MassStage IV Colorectal Cancer AJCC v7+2 more
M.D. Anderson Cancer Center 24
Testing effectiveness (Phase 2)Study completedNCT03797326
What this trial is testing

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)

Who this might be right for
Advanced Solid TumorsTriple Negative Breast CancerOvarian Cancer+5 more
Merck Sharp & Dohme LLC 611
Not applicableLooking for participantsNCT07829081
What this trial is testing

Research on Effective Strategies After Immunotherapy for Mismatch Repair-deficient Early-stage GI Tumors

Who this might be right for
Quality of Life (QOL)Mismatch Repair Deficient Colorectal CancerMicrosatellite Instability-High Colorectal Cancer+8 more
University Hospital, Basel, Switzerland 234
Early research (Phase 1)Study completedNCT02503774
What this trial is testing

MEDI9447 Alone and in Combination With MEDI4736 in Adult Participants With Select Advanced Solid Tumors.

Who this might be right for
Solid Tumors
MedImmune LLC 192
Large-scale testing (Phase 3)Study completedNCT04776148
What this trial is testing

Study of Lenvatinib (MK-7902/E7080) in Combination With Pembrolizumab (MK-3475) Versus Standard of Care in Participants With Metastatic Colorectal Cancer (MK-7902-017/E7080-G000-325/LEAP-017)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 563
Early research (Phase 1)UnknownNCT05780307
What this trial is testing

IMM2520, a PD-L1 and CD47 Bispecific Antibody in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorNon-small Cell Lung CancerSmall Cell Lung Cancer+3 more
ImmuneOnco Biopharmaceuticals (Shanghai) Inc. 48
Testing effectiveness (Phase 2)Study completedNCT02992912
What this trial is testing

Atezolizumab With Stereotactic Ablative Radiotherapy in Patients With Metastatic Tumours

Who this might be right for
Patients With Metastatic Tumours (Colorectal Cancer, Non-small Lung Cancer, Renal Cell Carcinoma or Sarcoma )
Gustave Roussy, Cancer Campus, Grand Paris 138
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