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Results for “Pembrolizumab”

2,156 trials

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Showing 20 of 2,156 results

Early research (Phase 1)Looking for participantsNCT02998567
What this trial is testing

Combination Study of Guadecitabine/ASTX727 and Pembrolizumab

Who this might be right for
Non Small Cell Lung Cancer
Royal Marsden NHS Foundation Trust 60
Large-scale testing (Phase 3)Study completedNCT01866319
What this trial is testing

Study to Evaluate the Safety and Efficacy of Two Different Dosing Schedules of Pembrolizumab (MK-3475) Compared to Ipilimumab in Participants With Advanced Melanoma (MK-3475-006/KEYNOTE-006)

Who this might be right for
Melanoma
Merck Sharp & Dohme LLC 834
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06814067
What this trial is testing

Phase II Multi-centered Study of Perioperative Ivonescimab Versus Pembrolizumab Combined with Standard of Care (SOC) in Patients with Resectable, Locally Advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell CarcinomaHead and Neck Squamous Cell Carcinoma HNSCC
Fudan University 80
Testing effectiveness (Phase 2)Study completedNCT03200847
What this trial is testing

Pembrolizumab and All-Trans Retinoic Acid Combination Treatment of Advanced Melanoma

Who this might be right for
Stage IV MelanomaStage III MelanomaAdvanced Melanoma
University of Colorado, Denver 26
Testing effectiveness (Phase 2)Study completedNCT02607631
What this trial is testing

Pembrolizumab for Patients With Thymic Epithelial Tumor

Who this might be right for
Thymic Epithelial Tumors
Samsung Medical Center 33
Testing effectiveness (Phase 2)Looking for participantsNCT06001658
What this trial is testing

Perioperative Gemcitabine, Cisplatin, and Pembrolizumab in Potentially Resectable Biliary Tract Cancers

Who this might be right for
Billiary Track Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 27
Testing effectiveness (Phase 2)Study completedNCT02260440
What this trial is testing

Pembrolizumab (MK-3475) in Combination With Azacitidine in Subjects With Chemo-refractory Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Anuradha Krishnamurthy 31
Testing effectiveness (Phase 2)Looking for participantsNCT05619913
What this trial is testing

EPOCH: Eribulin and Pembrolizumab in Ovarian/Uterine Carcinosarcoma

Who this might be right for
Ovarian CarcinosarcomaUterine Carcinosarcoma
Australia New Zealand Gynaecological Oncology Group 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT03854474
What this trial is testing

Testing the Addition of Tazemetostat to the Immunotherapy Drug, Pembrolizumab (MK-3475), in Advanced Urothelial Carcinoma

Who this might be right for
Locally Advanced Urothelial CarcinomaMetastatic Urothelial CarcinomaStage III Bladder Cancer AJCC v8+1 more
National Cancer Institute (NCI) 30
Testing effectiveness (Phase 2)Looking for participantsNCT04724018
What this trial is testing

Sacituzumab Govitecan Plus EV in Metastatic UC

Who this might be right for
Urothelial CancerMetastatic Urothelial CarcinomaMetastatic Urothelial Carcinoma of the Renal Pelvis and Ureter+1 more
Dana-Farber Cancer Institute 106
Testing effectiveness (Phase 2)WithdrawnNCT05234606
What this trial is testing

A Safety and Preliminary Efficacy Study of SBT6290 Alone and in Combination With PD-(L)1 Inhibitors in Select Advanced Solid Tumors

Who this might be right for
Urothelial CarcinomaTriple Negative Breast CancerNon-small Cell Lung Cancer+2 more
Silverback Therapeutics
Testing effectiveness (Phase 2)Active Not RecruitingNCT04393350
What this trial is testing

Perioperative Lenvatinib With Pembrolizumab in Patients With Locally Advanced Nonmetastatic Clear Cell Renal Cell Carcinoma

Who this might be right for
Kidney CancerStage III Renal Cell Cancer AJCC v8Stage IV Renal Cell Cancer AJCC v8
Emory University 18
Testing effectiveness (Phase 2)Looking for participantsNCT05420948
What this trial is testing

Pembrolizumab in Combination With Chemotherapy for Head and Neck Cancer

Who this might be right for
Head and Neck CancerHead and Neck Squamous Cell CarcinomaHead and Neck Neoplasms+2 more
University of Chicago 30
Early research (Phase 1)Study completedNCT03084640
What this trial is testing

Phase 1B Study Evaluating Alternative Routes of Administration of CMP-001 in Combination With Pembrolizumab in Participants With Advanced Melanoma

Who this might be right for
Malignant Melanoma
Regeneron Pharmaceuticals 30
Testing effectiveness (Phase 2)Looking for participantsNCT05101356
What this trial is testing

A Cancer Vaccine (Labvax 3(22)-23) and GM-CSF Alone or in Combination With Pembrolizumab for the Treatment of Advanced Stage Adenocarcinoma

Who this might be right for
Advanced AdenocarcinomaAdvanced Malignant Solid NeoplasmMetastatic Adenocarcinoma+3 more
Tianhong Li 77
Not applicableNot Yet RecruitingNCT06418139
What this trial is testing

Association of Pembrolizumab Infusion Time and Efficacy in Patients With Non-metastatic Triple-negative Breast Cancer (TNBC) Treated With Neoadjuvant Chemotherapy and Immunotherapy

Who this might be right for
Non-Metastatic Breast Carcinoma
Assistance Publique - Hôpitaux de Paris 450
Early research (Phase 1)WithdrawnNCT04605614
What this trial is testing

64Cu-DOTA-pembrolizumab PET for the Study of PD1 Expression

Who this might be right for
Hematopoietic and Lymphoid Cell NeoplasmMalignant Solid Neoplasm
City of Hope Medical Center
Testing effectiveness (Phase 2)Active Not RecruitingNCT05363631
What this trial is testing

Seleno-L Methionine (SLM)-Axitinib-Pembrolizumab

Who this might be right for
Clear Cell Renal Cell CarcinomaClear Cell Renal Cell Carcinoma Metastatic
Mohammed Milhem 55
Testing effectiveness (Phase 2)Ended earlyNCT05191472
What this trial is testing

Pembrolizumab for the Treatment of Relapsed or Refractory Multiple Myeloma After Anti-BCMA CAR-T Therapies

Who this might be right for
Multiple MyelomaMultiple Myeloma in RelapseMultiple Myeloma, Refractory+2 more
Alfred Chung, MD 3
Large-scale testing (Phase 3)UnknownNCT05042375
What this trial is testing

A Trial of Camrelizumab Combined With Famitinib Malate in Treatment Naïve Subjects With PD-L1-Positive Recurrent or Metastatic Non-Small Cell Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer
Jiangsu HengRui Medicine Co., Ltd. 450
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