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Results for “Pembrolizumab”

2,198 trials

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Showing 20 of 2,198 results

Early research (Phase 1)WithdrawnNCT03605589
What this trial is testing

Pembro + Blina Combination in Pediatric and Young Adult Patients With Relapsed/Refractory Acute Leukemia or Lymphoma

Who this might be right for
Leukemia, B-cellLymphoma, B-Cell
Children's Hospital Medical Center, Cincinnati
Post-approval studies (Phase 4)Study completedNCT04489888
What this trial is testing

Pembrolizumab (MK-3475) Plus Carboplatin and Paclitaxel as First-line Treatment of Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (MK-3475-B10/KEYNOTE B10)

Who this might be right for
Squamous Cell Carcinoma of Head and Neck
Merck Sharp & Dohme LLC 101
Testing effectiveness (Phase 2)Study completedNCT04383743
What this trial is testing

Pembrolizumab and Combination Chemotherapy Before Surgery for the Treatment of Muscle-Invasive Bladder Cancer

Who this might be right for
Stage II Bladder Cancer AJCC v8Stage IIIA Bladder Cancer AJCC v8Muscle Invasive Bladder Carcinoma
University of Washington 17
Testing effectiveness (Phase 2)WithdrawnNCT03832673
What this trial is testing

Pembrolizumab-Epacadostat Combination to Treat Muscle-invasive Bladder UrotheLIAl canceR: PECULIAR Study

Who this might be right for
Muscle-invasive Bladder Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Large-scale testing (Phase 3)Study completedNCT02819518
What this trial is testing

Study of Pembrolizumab (MK-3475) Plus Chemotherapy vs. Placebo Plus Chemotherapy for Previously Untreated Locally Recurrent Inoperable or Metastatic Triple Negative Breast Cancer (MK-3475-355/KEYNOTE-355)

Who this might be right for
Triple Negative Breast Cancer (TNBC)
Merck Sharp & Dohme LLC 882
Testing effectiveness (Phase 2)Active Not RecruitingNCT03516279
What this trial is testing

Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease

Who this might be right for
Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveMinimal Residual Disease
ECOG-ACRIN Cancer Research Group 40
Early research (Phase 1)WithdrawnNCT07217496
What this trial is testing

N-803 in Combination With Pembrolizumab and Enfortumab Vedotin for Treatment of Urothelial Cancer

Who this might be right for
Metastatic Urothelial CarcinomaUrothelial CarcinomaLocally Advanced Urothelial Carcinoma+1 more
Vadim S Koshkin
Testing effectiveness (Phase 2)Active Not RecruitingNCT06155279
What this trial is testing

Induction Chemo+Immunotherapy in Resectable Epithelioid and Biphasic Pleural Mesothelioma (CHIMERA Study)

Who this might be right for
Pleural Mesothelioma
Istituto Oncologico Veneto IRCCS 41
Testing effectiveness (Phase 2)Looking for participantsNCT06579196
What this trial is testing

Trabedersen (OT-101) With Pembrolizumab for Newly Diagnosed Advanced NSCLC and Positive PD-L1

Who this might be right for
Non-small Cell Lung Cancer
University of Nebraska 45
Large-scale testing (Phase 3)Not Yet RecruitingNCT07318883
What this trial is testing

A Phase II/III Clinical Study to Evaluate HLX07 in Combination With Serplulimab and Chemotherapy Versus Placebo in Combination With Serplulimab or Pembrolizumab and Chemotherapy as First-Line Treatment in Advanced Squamous Non-Small Cell Lung Cancer

Who this might be right for
Squamous NSCLC
Shanghai Henlius Biotech 720
Testing effectiveness (Phase 2)Looking for participantsNCT06157151
What this trial is testing

PRGN-2009 in Combination With Pembrolizumab in Patients With Recurrent or Metastatic Cervical Cancer

Who this might be right for
Cervical CancerHPV-Related CarcinomaHPV-Related Malignancy+2 more
Precigen, Inc 24
Testing effectiveness (Phase 2)Study completedNCT02705820
What this trial is testing

Switch Maintenance Pembrolizumab in Patients With NSCLC After First Line Platinum Doublet Chemotherapy

Who this might be right for
Metastatic Non Small Cell Lung Cancer
Bank of Cyprus Oncology Centre 48
Testing effectiveness (Phase 2)Ended earlyNCT05059470
What this trial is testing

IMRT Followed by Pembrolizumab in the Adjuvant Setting in Anaplastic Cancer of the Thyroid (IMPAACT): Phase II Trial Adjuvant Pembrolizumab After IMRT in ATC

Who this might be right for
Thyroid
M.D. Anderson Cancer Center 6
Testing effectiveness (Phase 2)Study completedNCT02365766
What this trial is testing

Neoadjuvant Pembrolizumab in Combination With Gemcitabine Therapy in Cis-eligible/Ineligible UC Subjects

Who this might be right for
Urothelial CarcinomaBladder Cancer
Jason R. Brown 83
Very early researchWithdrawnNCT03291353
What this trial is testing

Phase 0- Pilot Study of Pembrolizumab on Immune Cells in Patient With Refractory Acute Myeloid Leukemia

Who this might be right for
Refractory Acute Myeloid Leukemia
Michael Boyiadzis
Testing effectiveness (Phase 2)Study completedNCT02448303
What this trial is testing

Pembrolizumab Alone and In Combination With Acalabrutinib (ACP-196) in Subjects With Advanced Non-small Cell Lung Cancer

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Acerta Pharma BV 74
Testing effectiveness (Phase 2)Ended earlyNCT04268277
What this trial is testing

Pembrolizumab in MarginalzoneLymphoma A MULTICENTER OPEN LABEL SINGLE-ARM PHASE II STUDY

Who this might be right for
Marginal Zone Lymphoma
University of Ulm 22
Testing effectiveness (Phase 2)Study completedNCT03278665
What this trial is testing

4SC-202 in Combination With Pembrolizumab in Patients Primary Refractory/Non-responding to Prior Anti-PD-1 Therapy

Who this might be right for
Malignant Melanoma
4SC AG 40
Testing effectiveness (Phase 2)WithdrawnNCT07511972
What this trial is testing

Study of NGM707 in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies

Who this might be right for
CRC
NGM Biopharmaceuticals, Inc
Testing effectiveness (Phase 2)Active Not RecruitingNCT03488667
What this trial is testing

Perioperative mFOLFOX Plus Pembrolizumab in Gastroesophageal Junction (GEJ) and Stomach Adenocarcinoma

Who this might be right for
Gastro Esophageal Junction CancerStomach CancerAdenocarcinoma
University of Kansas Medical Center 40
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