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Results for “Pembrolizumab”

2,174 trials

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Showing 20 of 2,174 results

Large-scale testing (Phase 3)Looking for participantsNCT06989112
What this trial is testing

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Who this might be right for
Endometrial Cancer
AstraZeneca 600
Large-scale testing (Phase 3)Not Yet RecruitingNCT07365319
What this trial is testing

A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer.

Who this might be right for
Non Small Cell Lung Cancer (Squamous or Non Squamous)Stage 4 NSCLC
Eikon Therapeutics 750
Testing effectiveness (Phase 2)Looking for participantsNCT03645928
What this trial is testing

Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors

Who this might be right for
Metastatic MelanomaSquamous Cell Carcinoma of the Head and NeckNon-small Cell Lung Cancer
Iovance Biotherapeutics, Inc. 245
Large-scale testing (Phase 3)Looking for participantsNCT06939595
What this trial is testing

Compare Effects and Safety of CT-P51 and Keytruda in Patients With Previously Untreated Metastatic Lung Cancer

Who this might be right for
Non Squamous Non Small Cell Lung Cancer
Celltrion 606
Testing effectiveness (Phase 2)Ended earlyNCT02834975
What this trial is testing

Pembrolizumab, Paclitaxel, and Carboplatin in Patients With Advanced Stage Epithelial Ovarian Cancer (EOC).

Who this might be right for
Fallopian Tube CancerPeritoneum CancerEpithelial Ovarian Cancer
University of Miami 26
Testing effectiveness (Phase 2)UnknownNCT05201612
What this trial is testing

Pembrolizumab and Olaparib in Homologous-recombination Deficient (HRD) Advanced Colorectal Cancer (CRC).

Who this might be right for
Metastatic Colorectal Cancer
Grupo Espanol Multidisciplinario del Cancer Digestivo 40
Testing effectiveness (Phase 2)Study completedNCT02574598
What this trial is testing

MK-3475 in Combination With Docetaxel vs Docetaxel Alone in Non-Small Cell Lung Cancer Patients

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Instituto Nacional de Cancerologia de Mexico 78
Very early researchWithdrawnNCT04220892
What this trial is testing

Pilot Study of Pembrolizumab Combined With Pemetrexed or Abemaciclib for High Grade Glioma

Who this might be right for
High Grade Glioma
Jose Carrillo
Early research (Phase 1)Looking for participantsNCT04295863
What this trial is testing

Comparing Dosing Intervals of Nivolumab or Pembrolizumab in Locally Advanced or Metastatic Cancers

Who this might be right for
Metastatic Cancer
University of Chicago 264
Testing effectiveness (Phase 2)WithdrawnNCT03592407
What this trial is testing

Epacadostat and Pembrolizumab Before Surgery in Treating Participants With Stage II-III Esophageal or Gastroesophageal Cancer

Who this might be right for
Esophageal Squamous Cell CarcinomaEsophageal AdenocarcinomaGastroesophageal Junction Adenocarcinoma
City of Hope Medical Center
Early research (Phase 1)Active Not RecruitingNCT02521844
What this trial is testing

Evaluate the Safety and Tolerability of ETC-1922159 as a Single Agent and in Combination With Pembrolizumab in Advanced Solid Tumours

Who this might be right for
Solid Tumors
EDDC (Experimental Drug Development Centre), A*STAR Research Entities 89
Early research (Phase 1)Study completedNCT05585034
What this trial is testing

Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors

Who this might be right for
Head and Neck Squamous Cell CarcinomaMelanoma Excluding Uveal MelanomaNon-small Cell Lung Cancer, Squamous or Non-squamous+6 more
Xencor, Inc. 60
Early research (Phase 1)Study completedNCT03954067
What this trial is testing

An Intratumoral Oncolytic Virus in Patients With Advanced Metastatic Solid Tumors

Who this might be right for
Metastatic CancerSolid TumorsAdvanced Cancer
Astellas Pharma Global Development, Inc. 72
Testing effectiveness (Phase 2)Looking for participantsNCT07043972
What this trial is testing

Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma

Who this might be right for
Urothelial Carcinoma
Fox Chase Cancer Center 55
Early research (Phase 1)Ended earlyNCT03237572
What this trial is testing

Focused Ultrasound and Pembrolizumab in Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Patrick Dillon, MD 13
Testing effectiveness (Phase 2)WithdrawnNCT03221634
What this trial is testing

Efficacy and Safety Study of Pembrolizumab (MK-3475) in Combination With Daratumumab in Participants With Relapsed Refractory Multiple Myeloma (MK-3475-668/KEYNOTE-668)

Who this might be right for
Multiple Myeloma
Merck Sharp & Dohme LLC
Early research (Phase 1)Study completedNCT02054806
What this trial is testing

Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-028/KEYNOTE-28)

Who this might be right for
Solid Tumor
Merck Sharp & Dohme LLC 477
Testing effectiveness (Phase 2)Study completedNCT03631407
What this trial is testing

Safety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Microsatellite Stable (MSS) Colorectal Cancer (CRC) (MK-7690-046)

Who this might be right for
Colorectal Neoplasms
Merck Sharp & Dohme LLC 41
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05741164
What this trial is testing

Propranolol and Pembrolizumab for Tumor Re-sensitization and Treatment of Patients With Checkpoint Inhibitor Refractory Metastatic or Unresectable Triple Negative Breast Cancer

Who this might be right for
Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Metastatic Triple-Negative Breast Carcinoma+2 more
Emory University 37
Testing effectiveness (Phase 2)Active Not RecruitingNCT03225664
What this trial is testing

Trametinib and Pembrolizumab in Treating Patients With Recurrent Non-small Cell Lung Cancer That Is Metastatic, Unresectable, or Locally Advanced

Who this might be right for
Metastatic Lung Non-Small Cell CarcinomaRecurrent Lung Non-Small Cell CarcinomaStage III Lung Cancer AJCC v8+7 more
M.D. Anderson Cancer Center 37
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