Not applicableStudy completedNCT06589076What this trial is testingApical Periodontitis and Mental HealthWho this might be right forApical PeriodontitisAnxietyDepression University of Siena 120
Not applicableStudy completedNCT05847647What this trial is testingEvaluation of the Effect of Leukocyte and Platelet-rich Fibrin on Healing After Periradicular SurgeryWho this might be right forApical PeriodontitisPeriapical Lesion Seyda Ersahan, DDS, PhD 15
Not applicableStudy completedNCT05792787What this trial is testingAssociation Between Apical Periodontitis and Atherosclerotic Cardiovascular DiseasesWho this might be right forApical PeriodontitisAtherosclerotic Cardiovascular Disease University of Siena 65
Not applicableUnknownNCT04358887What this trial is testingEffect of Piezoelectric Surgery on Quality of Life and Periradicular Healing After Endodontic SurgeryWho this might be right forPeriapical Disease Postgraduate Institute of Dental Sciences Rohtak 40
Not applicableActive Not RecruitingNCT07387809What this trial is testingEffectiveness of Laser-activated Photoacoustic Flow in One-visit Revision of Teeth With Apical PeriodontitisWho this might be right forApical Periodontitis University of Zagreb 60
Not applicableNot Yet RecruitingNCT07762599What this trial is testingSilver Nanoparticle-Reinforced Double Antibiotic Paste in Symptomatic Apical Periodontitis: A Randomized Controlled TrialWho this might be right forApical PeriodontitisPost Endodontic PainPeriapical Healing+1 more All India Institute of Medical Sciences 50
Not applicableLooking for participantsNCT05439330What this trial is testingApplication of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alterations Related to Third Molars, Periapical and Periodontal Inflammatory Diseases, and Implant Treatment PlanningWho this might be right forTMJApical PeriodontitisPeriodontal Inflammation+2 more University of Aarhus 470
Post-approval studies (Phase 4)Not Yet RecruitingNCT06776289What this trial is testingEndodontic MicrosurgeryWho this might be right forApical Periodontitis Mark Schachman 20
Not applicableStudy completedNCT05297747What this trial is testingAdrenomedullin Upregulation in Apical PeriodontitisWho this might be right forPeriapical Periodontitis Istanbul Medipol University Hospital 174
Very early researchUnknownNCT05582421What this trial is testingEffect of Diclofenac Sodium Versus Calcium Hydroxide as Intracanal Medication on the Intensity of Postoperative Pain, Bacterial Load Reduction and MMP-9 Levels in Patients With Necrotic Pulp.Who this might be right forNecrotic PulpApical Periodontitis Cairo University 30
Not applicableStudy completedNCT07700394What this trial is testingDifferent Treatment Options For Mature Teeth With Apical PeriodontitisWho this might be right forApical Periodontitis Sara Tariq Elemam 30
Not applicableStudy completedNCT06339905What this trial is testingThe Effects of EndoActivator on Postoperative Pain and Root Canal Treatment SuccessWho this might be right forPeriapical PeriodontitisRoot Canal Infection Istanbul Medipol University Hospital 140
Not applicableStudy completedNCT05555043What this trial is testingComparison of Clinical Outcomes Between GentleWave® and Biolase®Who this might be right forEndodontic DiseasePeriapical DiseasesPeriapical Periodontitis+1 more University of North Carolina, Chapel Hill 120
Not applicableUnknownNCT06450938What this trial is testingNo Code Artificial Intelligence to Detect Radiographic Features Associated With Unsatisfactory Endodontic TreatmentWho this might be right forEndodontically Treated TeethEndodontic UnderfillEndodontic Overfill+1 more University of Copenhagen 80
Not applicableActive Not RecruitingNCT06949176What this trial is testingClinical Investigation of Chemomechanical Parameters for an Efficient Disinfection of the Root CanalWho this might be right forApical PeriodontitisRoot Canal Infection National and Kapodistrian University of Athens 44
Testing effectiveness (Phase 2)Study completedNCT06342830What this trial is testingComparing the Effect of Different Intracanal Dressing on Failed Root Canal Treated Cases on Periapical HealingWho this might be right forPeriapical Disease Ain Shams University 60
Not applicableLooking for participantsNCT07019298What this trial is testingSuccess of Endodontic Treatment With Different Obturation Techniques and Sealer CementsWho this might be right forPulpitisPeriapical LesionsPeriapical Periodontitis+1 more University of Siena 270
Not applicableStudy completedNCT07653997What this trial is testingThe MTA Effect on Healing and Biomarkers in Endo-Perio LesionsWho this might be right forEndodontic-Periodontal LesionsApical PeriodontitisPeriapical Disease Istanbul Medipol University Hospital 120
Post-approval studies (Phase 4)UnknownNCT06384014What this trial is testingExamining the Effect of Different Filling Techniques on Healing in Lesional TeethWho this might be right forApical Cyst TC Erciyes University 60
Not applicableStudy completedNCT02528240What this trial is testingEndodontic Microsurgery With the Use of L-PRF and an Occlusive Membrane: a Randomized Controlled Clinical TrialWho this might be right forPeriapical Periodontitis Universitaire Ziekenhuizen KU Leuven 56