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Results for “Phase 1 Pharmacodynamic Study”

2,552 trials

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Showing 20 of 2,552 results

Early research (Phase 1)Study completedNCT02156544
What this trial is testing

Study to Investigate the Safety/Tolerability and Pharmacokinetics/Pharmacodynamics of CKD-519

Who this might be right for
Dyslipidemia
Chong Kun Dang Pharmaceutical 41
Testing effectiveness (Phase 2)Study completedNCT02650193
What this trial is testing

The Safety And Effects Of One Or More Doses Of HSP-130 Injected Under The Skin In Women With Breast Cancer That Has Not Spread To Distant Sites In The Body.

Who this might be right for
Non-metastatic Breast Cancer
Pfizer 25
Early research (Phase 1)Ended earlyNCT01534949
What this trial is testing

Provide Initial Evidence of Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy to Support the Pivotal CT-P10 Therapeutic Equivalence Trial

Who this might be right for
Diffuse Large B-Cell Lymphoma
Celltrion 1
Testing effectiveness (Phase 2)Study completedNCT03516487
What this trial is testing

Safety and Tolerability of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria

Who this might be right for
PhenylketonuriaHealthy
Synlogic 70
Testing effectiveness (Phase 2)Active Not RecruitingNCT04416984
What this trial is testing

Safety and Efficacy of ALLO-501A Anti-CD19 Allogeneic CAR T Cells in Adults with Relapsed/Refractory Large B Cell Lymphoma, Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (ALPHA2)

Who this might be right for
Relapsed or Refractory Large B Cell Lymphoma, Relapsed or Refractory Chronic Lymphocytic Leukemia, Relapsed or Refractory Small Lymphocytic Lymphoma
Allogene Therapeutics 160
Early research (Phase 1)Ended earlyNCT00147485
What this trial is testing

An Intravenously Administered Cyclin-Dependent Kinase Inhibitor In Patients With Advanced Cancer

Who this might be right for
NeoplasmsLymphoma, Non-Hodgkin
Pfizer 37
Early research (Phase 1)Study completedNCT05249621
What this trial is testing

Phase 1 of of MZE001 in Healthy Volunteers

Who this might be right for
Healthy
Maze Therapeutics 121
Testing effectiveness (Phase 2)Looking for participantsNCT05970016
What this trial is testing

A Phase I/II Clinical Study in Patients with Advanced Solid Tumor.

Who this might be right for
Patients with Advanced Solid Tumors
Beijing Tide Pharmaceutical Co., Ltd 56
Early research (Phase 1)Study completedNCT00754143
What this trial is testing

Phase 1 Study of FG-3019 in Subjects With Type 1 or Type 2 Diabetes Mellitus and Diabetic Nephropathy

Who this might be right for
Diabetes MellitusDiabetic Nephropathy
Kyntra Bio 38
Early research (Phase 1)Study completedNCT02321644
What this trial is testing

Effect of UV Exposure on the PD of Multiple Doses of CC-90001 and Pilot Food Effect Study

Who this might be right for
Healthy Subjects
Celgene Corporation 26
Early research (Phase 1)Active Not RecruitingNCT05614102
What this trial is testing

A First-in-human Study to Learn How Safe the Study Drug BAY2965501 is, Find the Best Dose (Single Drug & Combination), How it Affects the Body, What Maximum Amount Can be Given, How it Moves Into, Through and Out of the Body, How it Acts on Different Tumors in Participants With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Bayer 284
Early research (Phase 1)UnknownNCT04587011
What this trial is testing

Explore Pharmacokinetics/Pharmacodynamics and Safety of Tegoprazan BID Dosing in Healthy Subjects

Who this might be right for
Healthy
HK inno.N Corporation 40
Early research (Phase 1)Study completedNCT01582399
What this trial is testing

Bioavailability of ASKP1240 in Healthy Subjects After Intravenous and Subcutaneous Administration of ASKP1240

Who this might be right for
Pharmacokinetics of ASKP1240Pharmacodynamics of ASKP1240Healthy Volunteers
Astellas Pharma Global Development, Inc. 24
Early research (Phase 1)Study completedNCT04268784
What this trial is testing

Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL343 in Healthy Volunteers

Who this might be right for
Healthy Volunteers
Denali Therapeutics Inc. 96
Early research (Phase 1)Study completedNCT01054300
What this trial is testing

Effects of Once and Twice Daily Dosing Regimen of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-040)

Who this might be right for
Diabetes Mellitus, Type 2Adult
Merck Sharp & Dohme LLC 52
Testing effectiveness (Phase 2)Looking for participantsNCT05994534
What this trial is testing

PK and PD Study of NPI-001 and Cysteamine Bitartrate

Who this might be right for
Cystinosis
Nacuity Pharmaceuticals, Inc. 12
Early research (Phase 1)Study completedNCT00679133
What this trial is testing

Safety Study of Oral MGCD265 Administered With Interruption to Subjects With Advanced Malignancies

Who this might be right for
Advanced Malignancies
Mirati Therapeutics Inc. 47
Early research (Phase 1)Study completedNCT02572349
What this trial is testing

Trial of IW-1701 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy Volunteers

Who this might be right for
Healthy
Cyclerion Therapeutics 24
Testing effectiveness (Phase 2)Study completedNCT03945292
What this trial is testing

Safety, Tolerability and Pharmacodynamic Effect of Fazirsiran (TAK-999, ARO-AAT)

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Arrowhead Pharmaceuticals 40
Early research (Phase 1)Study completedNCT03797664
What this trial is testing

The Safety and Tolerability of CDX-6114 in Healthy Volunteers

Who this might be right for
Healthy
Codexis Inc. 32
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