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Results for “Phase 1 Pharmacodynamic Study”

2,750 trials

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Showing 20 of 2,750 results

Early research (Phase 1)Study completedNCT02919800
What this trial is testing

A Single-dose, Dose-escalation Study of a Long-acting MOD-5014 in Healthy Adult Male

Who this might be right for
Hemophilia A or B With Inhibitors
OPKO Health, Inc. 32
Testing effectiveness (Phase 2)Study completedNCT00331136
What this trial is testing

Pyronaridine and Artesunate (3:1) in Children With Acute Uncomplicated Plasmodium Falciparum Malaria

Who this might be right for
Uncomplicated Plasmodium Falciparum Malaria
Medicines for Malaria Venture 60
Early research (Phase 1)Study completedNCT01772836
What this trial is testing

Safety Study of Intravenous Biapenem (RPX2003) and RPX7009 Given Alone and in Combination

Who this might be right for
Healthy VolunteersBacterial Infections
Rempex Pharmaceuticals (a wholly owned subsidiary of The Medicines Company) 30
Early research (Phase 1)Looking for participantsNCT07229911
What this trial is testing

TAK-781 in Healthy Volunteers and in Participants With Non-Cirrhotic Primary Sclerosing Cholangitis (PSC)

Who this might be right for
Healthy VolunteersPrimary Sclerosing Cholangitis
Takeda 134
Early research (Phase 1)Looking for participantsNCT07280936
What this trial is testing

SHR-2906 Injection in Healthy Subjects With a Single Dose and in Obese Patients With Multiple Doses

Who this might be right for
ObesityOverweight
Beijing Suncadia Pharmaceuticals Co., Ltd 124
Early research (Phase 1)Study completedNCT01195311
What this trial is testing

A Dose-escalation Study in Subjects With Advanced Malignancies

Who this might be right for
Solid Tumors and Hematologic Malignancy
Incyte Corporation 52
Early research (Phase 1)Ended earlyNCT01923389
What this trial is testing

Multiple Dose Study Of PF-05231023 In Obese Adult Subjects

Who this might be right for
Type 2 Diabetes Mellitus (T2DM)
Pfizer 4
Early research (Phase 1)Study completedNCT05677035
What this trial is testing

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LINO-1713 in Healthy Korean Female Subjects

Who this might be right for
Contraception
Hyundai Pharm 20
Testing effectiveness (Phase 2)Looking for participantsNCT04585750
What this trial is testing

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

Who this might be right for
Advanced Solid TumorAdvanced Malignant NeoplasmMetastatic Cancer+27 more
PMV Pharmaceuticals, Inc 300
Early research (Phase 1)Active Not RecruitingNCT06421935
What this trial is testing

M9466 Alone or in Combination in Advanced Solid Tumors (DDriver 501)

Who this might be right for
Advanced Solid Tumor
EMD Serono Research & Development Institute, Inc. 60
Early research (Phase 1)Study completedNCT06435676
What this trial is testing

Single and Multiple Doses HRS9531 Tablets in Healthy Subjects

Who this might be right for
Overweight or Obesity; Type 2 Diabetes
Fujian Shengdi Pharmaceutical Co., Ltd. 72
Early research (Phase 1)Looking for participantsNCT07225517
What this trial is testing

Learn More About the Safety of BIIB145 and How it is Processed in the Body of Healthy Adult Participants

Who this might be right for
Healthy Volunteer
Biogen 104
Early research (Phase 1)Study completedNCT06721091
What this trial is testing

Safety, Tolerability, and Dose Response of VNA-318 in Healthy Males

Who this might be right for
Healthy Volunteer
VANDRIA 92
Early research (Phase 1)Looking for participantsNCT07107490
What this trial is testing

A PHASE I STUDY OF ALPS12 IN PATIENTS WITH EXTENSIVE STAGE SMALL CELL LUNG CANCER

Who this might be right for
Extensive Stage Small Cell Lung Cancer
Chugai Pharmaceutical 122
Early research (Phase 1)Looking for participantsNCT07755397
What this trial is testing

First in Human Multicenter Open Name Dose-increase, Consolidation Method to Study Safety Drug-level in Blood & Drug Metabolism Clinical Activity of Oral JBI-778 in Lung Cancer Patients With, Without Brain Metastasis IDH Mutated WHO Grade 3,4 Recurrent Glioma, Salivary Glands Tumor

Who this might be right for
NSCLC Patients With EGFR Activating MutationAdenoid Cystic Carcinoma MetastaticAdenoid Cystic Carcinoma of the Head and Neck
Jubilant Therapeutics India Limited 30
Early research (Phase 1)Study completedNCT01170897
What this trial is testing

Study of PEGPH20 With Initial Dexamethasone Premedication Given Intravenously to Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Halozyme Therapeutics 27
Early research (Phase 1)Study completedNCT06200597
What this trial is testing

A Single and Multiple Ascending Dose Study of LAD603 in Healthy Subjects

Who this might be right for
Healthy Volunteers
Almirall, S.A. 92
Early research (Phase 1)Looking for participantsNCT06980597
What this trial is testing

OL-108 in Relapsed/Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus Erythematosus (SLE)Idiopathic Inflammatory Myopathy (IIM)Systemic Sclerosis (SSc)+1 more
Beijing GoBroad Hospital 44
Early research (Phase 1)Study completedNCT00924105
What this trial is testing

Safety, Tolerability and Pharmacodynamics of CYT013-IL1bQb in Patients With Type 2 Diabetes

Who this might be right for
Type 2 Diabetes Mellitus
Cytos Biotechnology AG 48
Early research (Phase 1)Study completedNCT01133522
What this trial is testing

Ascending Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Evolocumab (AMG 145) in Adults With Hyperlipidemia on Stable Doses of a Statin

Who this might be right for
Hyperlipidemia
Amgen 60
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