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Results for “Phase 1b”

2,585 trials

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Showing 20 of 2,585 results

Testing effectiveness (Phase 2)WithdrawnNCT05279859
What this trial is testing

Anti-Cancer Therapies Targeting the MAPK Pathway in Patients With Hematologic Malignancies

Who this might be right for
Acute Myeloid Leukemia
Erasca, Inc.
Testing effectiveness (Phase 2)Study completedNCT04181788
What this trial is testing

Sasanlimab (PF-06801591, PD-1 Inhibitor) in Participants With Advanced Malignancies

Who this might be right for
Advanced MalignanciesNon-small-cell Lung Cancer
Pfizer 155
Early research (Phase 1)Study completedNCT06385327
What this trial is testing

Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes

Who this might be right for
Recurrent Genital Herpes Simplex Type 2
Assembly Biosciences 115
Early research (Phase 1)Study completedNCT02914470
What this trial is testing

Carboplatin-cyclophosphamide Combined With Atezolizumab

Who this might be right for
Breast CancerCervix CancerOvarian Cancer+1 more
The Netherlands Cancer Institute 12
Early research (Phase 1)Study completedNCT03418922
What this trial is testing

Lenvatinib Plus Nivolumab in Participants With Hepatocellular Carcinoma

Who this might be right for
Carcinoma, Hepatocellular
Eisai Co., Ltd. 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05383196
What this trial is testing

Onvansertib + Paclitaxel In TNBC

Who this might be right for
Breast CancerInvasive Breast CancerUnresectable Breast Carcinoma+7 more
Antonio Giordano, MD 50
Testing effectiveness (Phase 2)Looking for participantsNCT05784688
What this trial is testing

Study of TU2218 in Combination With KEYTRUDA®(Pembrolizumab) in Patients With Advanced Solid Tumors

Who this might be right for
Solid TumorBiliary Tract CancerHead and Neck Squamous Cell Carcinoma+1 more
TiumBio Co., Ltd. 140
Early research (Phase 1)WithdrawnNCT03772288
What this trial is testing

TAK-659 in Combination With NKTR-214 in Participants With Advanced Non-Hodgkin Lymphoma (NHL)

Who this might be right for
Lymphoma, Non-Hodgkin
Calithera Biosciences, Inc
Early research (Phase 1)Study completedNCT02069145
What this trial is testing

Dose Escalation Study of OMP-54F28 in Combination With Sorafenib in Patients With Hepatocellular Cancer

Who this might be right for
Hepatocellular CancerLiver Cancer
OncoMed Pharmaceuticals, Inc. 10
Early research (Phase 1)Ended earlyNCT03471286
What this trial is testing

A Window of Opportunity Study to Investigate Mechanisms of Actions of Novel Therapeutic Agents in Patients With Resectable Solid Tumor Malignancies

Who this might be right for
Solid Tumor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 2
Testing effectiveness (Phase 2)Study completedNCT05383170
What this trial is testing

Evaluate the Safety and Efficacy of CyPep-1 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic Cancers

Who this might be right for
Advanced Head and Neck Squamous Cell CarcinomaAdvanced Breast CancerAdvanced Melanoma
Cytovation AS 6
Early research (Phase 1)Active Not RecruitingNCT05784441
What this trial is testing

JNJ-90009530 in Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (r/r B-NHL)

Who this might be right for
Relapsed or Refractory B Cell Non-Hodgkin Lymphoma
Janssen Research & Development, LLC 21
Early research (Phase 1)Ended earlyNCT04893551
What this trial is testing

Tilvestamab (BGB149) in Relapsed, Platinum-resistant, High-grade Serous Ovarian Cancer (HGSOC) Participants

Who this might be right for
Ovarian Neoplasms
BerGenBio ASA 16
Testing effectiveness (Phase 2)Active Not RecruitingNCT06106672
What this trial is testing

Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of CNP-106 in Subjects With Myasthenia Gravis

Who this might be right for
Myasthenia GravisGeneralized MyastheniaAChR Myasthenia Gravis+1 more
COUR Pharmaceutical Development Company, Inc. 54
Testing effectiveness (Phase 2)Study completedNCT00630786
What this trial is testing

Conatumumab/Panitumumab Combination Metastatic Colorectal Cancer Study

Who this might be right for
Colon CancerColorectal CancerRectal Cancer+2 more
Amgen 53
Testing effectiveness (Phase 2)UnknownNCT04485260
What this trial is testing

An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 Combined With Ruxolitinib in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV-MF), Or Post-Essential Thrombocythemia MF (Post ET-MF) Who Have a Suboptimal Response to Ruxolitinib

Who this might be right for
Myelofibrosis
Kartos Therapeutics, Inc. 36
Early research (Phase 1)WithdrawnNCT05952687
What this trial is testing

Trial of Idasanutlin and Selinexor Therapy for Children With Progressive/Relapsed AT/RT or Extra-CNS Malignant Rhabdoid Tumors

Who this might be right for
Rhabdoid TumorAtypical Teratoid/Rhabdoid TumorAtypical Teratoid/Rhabdoid Tumor of CNS+1 more
St. Jude Children's Research Hospital
Early research (Phase 1)Not Yet RecruitingNCT07813130
What this trial is testing

A Phase 1b Study to Assess the Safety and Tolerability of AB126 Neural Exosomes in Patients With Moderate to Severe Acute Ischemic Stroke

Who this might be right for
Acute Ischemic Stroke
Aruna Bio, Inc. 20
Early research (Phase 1)Active Not RecruitingNCT05371964
What this trial is testing

Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Imetelstat in Combination With Ruxolitinib in Participants With Myelofibrosis

Who this might be right for
Myelofibrosis
Geron Corporation 30
Early research (Phase 1)Study completedNCT02754609
What this trial is testing

Hookworm Therapy for Coeliac Disease

Who this might be right for
Celiac Disease
James Cook University, Queensland, Australia 54
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