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Results for “Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia”

175 trials

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Showing 20 of 175 results

Not applicableUnknownNCT02034656
What this trial is testing

Patterns of ABL Mutation in Asian With Imatinib Resistant Chronic Myeloid Leukemia and Ph Positive Acute Lymphocytc Leuekmia Patients (AMICA)

Who this might be right for
Chronic Myeloid Leukemia or Ph Positive ALL
Seoul St. Mary's Hospital 125
Testing effectiveness (Phase 2)Study completedNCT01279473
What this trial is testing

Study to Evaluate Nilotinib in Adult Patients With Imatinib-resistant or Imatinib-intolerant Chronic Myelogenous Leukemia (CML), or Relapse/Refractory Ph+ Acute Lymphoblastic Leukemia (ALL) (Extension Study)

Who this might be right for
Chronic Myelogenous LeukemiaAcute Lymphoblastic Leukemia
Novartis Pharmaceuticals 42
Testing effectiveness (Phase 2)Study completedNCT01310010
What this trial is testing

Study of Dasatinib to Treat Philadelphia Positive Acute Lymphoblastic Leukemia

Who this might be right for
Leukemia, Lymphoblastic, Acute, Philadelphia-Positive
Grupo Espanol de trasplantes hematopoyeticos y terapia celular 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07301424
What this trial is testing

Subcutaneous Blinatumomab Plus Ponatinib for BCR-ABL+ B-ALL

Who this might be right for
Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+)BCR-ABL Positive Acute Lymphoblastic Leukemia
University of Alberta 80
Early research (Phase 1)Looking for participantsNCT03595917
What this trial is testing

ABL001 + Dasatinib + Prednisone + Blinatumomab in BCR-ABL+ B-ALL or CML

Who this might be right for
B-cell Acute Lymphoblastic LeukemiaChronic Myeloid Leukemia (CML) in Lymphoid Blast CrisisPhiladelphia Chromosome Positive Acute Lymphoblastic Leukemia Ph+ ALL
Marlise Luskin, MD 40
Early research (Phase 1)Active Not RecruitingNCT04872790
What this trial is testing

Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia

Who this might be right for
B Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1Mixed Phenotype Acute Leukemia+2 more
OHSU Knight Cancer Institute 20
Early research (Phase 1)Ended earlyNCT03519984
What this trial is testing

EphB4-HSA Fusion Protein and Cytarabine /or Liposomal Vincristine in Patients With Recurrent or Refractory Acute Leukemia

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeBlasts 5 Percent or More of Bone Marrow Nucleated CellsMyelodysplastic/Myeloproliferative Neoplasm+8 more
University of Southern California 3
Post-approval studies (Phase 4)Ended earlyNCT05071482
What this trial is testing

Flumatinib Versus Imatinib Combined With Chemotherapy for de Novo Ph+ ALL

Who this might be right for
Acute Leukemia
Institute of Hematology & Blood Diseases Hospital, China 39
Early research (Phase 1)Study completedNCT00807677
What this trial is testing

Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaChronic Myelogenous Leukemia+9 more
Millennium Pharmaceuticals, Inc. 31
Not applicableStudy completedNCT00003538
What this trial is testing

Prevention of Graft-Versus-Host Disease in Patients Undergoing Bone Marrow Transplantation

Who this might be right for
Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Testing effectiveness (Phase 2)Study completedNCT01207440
What this trial is testing

Ponatinib for Chronic Myeloid Leukemia (CML) Evaluation and Ph+ Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
Chronic Myeloid LeukemiaPh+ Acute Lymphoblastic Leukemia
Ariad Pharmaceuticals 449
Testing effectiveness (Phase 2)Study completedNCT00618501
What this trial is testing

Imatinib Mesylate and Combination Chemotherapy With or Without a Donor Stem Cell Transplant in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Who this might be right for
Leukemia
Asan Medical Center 50
Testing effectiveness (Phase 2)Looking for participantsNCT06308588
What this trial is testing

Phase I/II Study of the Combination of Blinatumomab and Asciminib in Patients With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Who this might be right for
Philadelphia Chromosome-PositiveAcute Lymphoblastic Leukemia
M.D. Anderson Cancer Center 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT02143414
What this trial is testing

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1+2 more
National Cancer Institute (NCI) 53
Not applicableNot Yet RecruitingNCT07356960
What this trial is testing

Evaluation of the Efficacy of Ponatinib in Ph+ ALL in the Real-world

Who this might be right for
Acute Lymphobkastic LeukemiaPhiladelphia Chromosome Positive Acute Lymphoblastic Leukemia
Gruppo Italiano Malattie EMatologiche dell'Adulto 103
Early research (Phase 1)Study completedNCT01159028
What this trial is testing

Clinical Trial of BP1001 (L-Grb-2 Antisense Oligonucleotide) in CML, AML, ALL & MDS

Who this might be right for
Recurrent Adult Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMyelodysplastic Syndrome+1 more
Bio-Path Holdings, Inc. 60
Early research (Phase 1)Ended earlyNCT00464113
What this trial is testing

Study of XL228 in Subjects With Chronic Myeloid Leukemia or Philadelphia-Chromosome-Positive Acute Lymphocytic Leukemia

Who this might be right for
Chronic Myeloid LeukemiaLeukemia, Lymphoblastic, Acute, Philadelphia-Positive
Exelixis 49
Not applicableStudy completedNCT01085617
What this trial is testing

Standard Chemotherapy with or Without Nelarabine or Rituximab in Treating Patients with Newly Diagnosed Acute Lymphoblastic Leukemia

Who this might be right for
LeukemiaMucositisOral Complications
University College, London
Not applicableEnded earlyNCT00608517
What this trial is testing

Treatment of Single or Double Umbilical Cord Trans + Graft-versus-host Disease (GVHD) Prophylaxis w/ Tacrolimus & Mycophenolate Mofetil

Who this might be right for
Graft Versus Host DiseaseLeukemiaLymphoma+2 more
Vanderbilt-Ingram Cancer Center 6
Testing effectiveness (Phase 2)Study completedNCT00844298
What this trial is testing

Nilotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Who this might be right for
Leukemia
Asan Medical Center 91
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