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Results for “Pretomanid”

32 trials

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Showing 20 of 32 results

Early research (Phase 1)Study completedNCT04309656
What this trial is testing

Single-dose Study in Two Panels of Healthy Adult Participants to Assess Immediate-Release and Dispersible Formulations of Pretomanid

Who this might be right for
Multi-drug Resistant Tuberculosis
Global Alliance for TB Drug Development 48
Testing effectiveness (Phase 2)Study completedNCT01691534
What this trial is testing

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z)

Who this might be right for
Pulmonary Tuberculosis
Global Alliance for TB Drug Development 105
Testing effectiveness (Phase 2)Study completedNCT04179500
What this trial is testing

A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Pulmonary Tuberculosis

Who this might be right for
Tuberculosis, PulmonaryTuberculosis, Multidrug-ResistantTuberculosis, MDR+2 more
Global Alliance for TB Drug Development 26
Early research (Phase 1)Study completedNCT01768273
What this trial is testing

Evaluation of the Pharmacokinetic Interaction Between PA-824 and Midazolam

Who this might be right for
Tuberculosis
Global Alliance for TB Drug Development 14
Large-scale testing (Phase 3)Study completedNCT03338621
What this trial is testing

Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult Patients

Who this might be right for
Tuberculosis, PulmonaryTuberculosis, Multidrug-ResistantTuberculosis, MDR+2 more
Global Alliance for TB Drug Development 455
Large-scale testing (Phase 3)Looking for participantsNCT07209761
What this trial is testing

Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary Tuberculosis

Who this might be right for
Pulmonary Tuberculosis
Otsuka Pharmaceutical Development & Commercialization, Inc. 532
Large-scale testing (Phase 3)Study completedNCT04207112
What this trial is testing

Economic Evaluation of New MDR TB Regimens

Who this might be right for
Multi-drug Resistant TuberculosisExtensively Drug-Resistant TuberculosisPulmonary Tuberculoses
Medecins Sans Frontieres, Netherlands 73
Early research (Phase 1)Ended earlyNCT02422524
What this trial is testing

Pretomanid in Adults With Hepatic Impairment

Who this might be right for
Tuberculosis
National Institute of Allergy and Infectious Diseases (NIAID) 14
Testing effectiveness (Phase 2)Study completedNCT00567840
What this trial is testing

PA-824-CL-007: Phase IIa Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis

Who this might be right for
Pulmonary Tuberculosis
Global Alliance for TB Drug Development 69
Testing effectiveness (Phase 2)Study completedNCT00944021
What this trial is testing

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis (CL-010)

Who this might be right for
Pulmonary Tuberculosis
Global Alliance for TB Drug Development 69
Testing effectiveness (Phase 2)Active Not RecruitingNCT06058299
What this trial is testing

Phase 2 Trial Assessing TBAJ876 or Bedaquiline, with Pretomanid and Linezolid in Adults with Drug-sensitive Pulmonary Tuberculosis

Who this might be right for
Pulmonary TBPulmonary TuberculosisDrug Sensitive Tuberculosis
Global Alliance for TB Drug Development 309
Large-scale testing (Phase 3)Looking for participantsNCT06441006
What this trial is testing

Program for Rifampicin-Resistant Disease With Stratified Medicine for Tuberculosis

Who this might be right for
Tuberculosis, PulmonaryTuberculosis, Multidrug-ResistantTuberculosis, MDR
University of California, San Francisco 400
Testing effectiveness (Phase 2)Looking for participantsNCT07517445
What this trial is testing

Bactericidal Activity and Safety of Nicotinamide in Combination With Bedaquiline, Pretomanid, and Linezolid in Drug-susceptible Pulmonary Tuberculosis

Who this might be right for
Drug Susceptible Pulmonary Tuberculosis
Gates Medical Research Institute 165
Early research (Phase 1)Study completedNCT03896750
What this trial is testing

Single-Dose Study to Evaluate the PKs of Pretomanid in Participants With Renal Impairment Compared to Participants With Normal Renal Function

Who this might be right for
Renal ImpairmentTuberculosis
National Institute of Allergy and Infectious Diseases (NIAID) 12
Not applicableStudy completedNCT05609552
What this trial is testing

Biodistribution and Pharmacokinetics of Pretomanid in Tuberculosis Patients Using 18F-Pretomanid PET

Who this might be right for
Tuberculosis
Johns Hopkins University 10
Testing effectiveness (Phase 2)Study completedNCT01498419
What this trial is testing

Evaluation of 8 Weeks of Treatment With the Combination of Moxifloxacin, PA-824 and Pyrazinamide in Patients With Drug Sensitive and Multi Drug-Resistant Pulmonary Tuberculosis (TB) (NC-002)

Who this might be right for
Pulmonary Tuberculosis
Global Alliance for TB Drug Development 207
Early research (Phase 1)Study completedNCT01828827
What this trial is testing

Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects

Who this might be right for
Tuberculosis
Global Alliance for TB Drug Development 16
Testing effectiveness (Phase 2)Study completedNCT02193776
What this trial is testing

To Evaluate the Efficacy, Safety and Tolerability of Combinations of Bedaquiline, Moxifloxacin, PA-824 and Pyrazinamide in Adult Subjects With Drug-Sensitive or Multi Drug-Resistant Pulmonary Tuberculosis.

Who this might be right for
Tuberculosis
Global Alliance for TB Drug Development 240
Testing effectiveness (Phase 2)Ended earlyNCT05971602
What this trial is testing

Efficacy and Safety Evaluation of Two to Four Months of Treatment With the Combination Regimens of DBOS and PBOS in Adults With Pulmonary Tuberculosis

Who this might be right for
Pulmonary Tuberculosis
Gates Medical Research Institute 93
Not applicableLooking for participantsNCT06471088
What this trial is testing

Safety and Efficacy Evaluation of <Dovprela Tablets 200 mg> by Post-marketing Surveillance

Who this might be right for
Dovprela
Viatris Inc. 100
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