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Results for “Pretomanid”

33 trials

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Showing 20 of 33 results

Testing effectiveness (Phase 2)Study completedNCT01215851
What this trial is testing

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With(J-M-Pa-Z) (NC-001)

Who this might be right for
Pulmonary Tuberculosis
Global Alliance for TB Drug Development 85
Testing effectiveness (Phase 2)Study completedNCT00567840
What this trial is testing

PA-824-CL-007: Phase IIa Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis

Who this might be right for
Pulmonary Tuberculosis
Global Alliance for TB Drug Development 69
Not applicableUnknownNCT06471088
What this trial is testing

Safety and Efficacy Evaluation of <Dovprela Tablets 200 mg> by Post-marketing Surveillance

Who this might be right for
Dovprela
Viatris Inc. 100
Not applicableNot Yet RecruitingNCT07126639
What this trial is testing

A Study on the Short-course Treatment Regimen Containing Pretomanid for Drug-resistant Tuberculosis

Who this might be right for
Efficacy and Safety
Wuhan Pulmonary Hospital 200
Large-scale testing (Phase 3)UnknownNCT04081077
What this trial is testing

PRACTECAL-PKPD Sub Study

Who this might be right for
Multi-drug Resistant TuberculosisExtensively Drug-Resistant TuberculosisPulmonary Tuberculosis
Medecins Sans Frontieres, Netherlands 240
Testing effectiveness (Phase 2)Study completedNCT01498419
What this trial is testing

Evaluation of 8 Weeks of Treatment With the Combination of Moxifloxacin, PA-824 and Pyrazinamide in Patients With Drug Sensitive and Multi Drug-Resistant Pulmonary Tuberculosis (TB) (NC-002)

Who this might be right for
Pulmonary Tuberculosis
Global Alliance for TB Drug Development 207
Large-scale testing (Phase 3)Study completedNCT03086486
What this trial is testing

Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis

Who this might be right for
Tuberculosis, PulmonaryTuberculosis, Multidrug-ResistantTuberculosis, MDR+4 more
Global Alliance for TB Drug Development 181
Early research (Phase 1)Study completedNCT01830439
What this trial is testing

Food Effect Study on the Bioavailability and PK of PA-824 Tablets in Healthy Adult Subjects (CL-009)

Who this might be right for
Tuberculosis
Global Alliance for TB Drug Development 32
Testing effectiveness (Phase 2)Study completedNCT01691534
What this trial is testing

Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z)

Who this might be right for
Pulmonary Tuberculosis
Global Alliance for TB Drug Development 105
Early research (Phase 1)Study completedNCT05586230
What this trial is testing

Study of a Single Dose of Pretomanid Added to an Optimized Background Regimen in Children With Rifampicin-Resistant Tuberculosis

Who this might be right for
TuberculosisRifampicin Resistant Tuberculosis
National Institute of Allergy and Infectious Diseases (NIAID) 32
Testing effectiveness (Phase 2)Looking for participantsNCT07672405
What this trial is testing

Sorfequiline-based Regimens in Adults With Newly Diagnosed Drug-sensitive Pulmonary TB

Who this might be right for
Tuberculosis, Pulmonary
Global Alliance for TB Drug Development 100
Early research (Phase 1)Study completedNCT03896750
What this trial is testing

Single-Dose Study to Evaluate the PKs of Pretomanid in Participants With Renal Impairment Compared to Participants With Normal Renal Function

Who this might be right for
Renal ImpairmentTuberculosis
National Institute of Allergy and Infectious Diseases (NIAID) 12
Early research (Phase 1)Study completedNCT04309656
What this trial is testing

Single-dose Study in Two Panels of Healthy Adult Participants to Assess Immediate-Release and Dispersible Formulations of Pretomanid

Who this might be right for
Multi-drug Resistant Tuberculosis
Global Alliance for TB Drug Development 48
Not applicableNot Yet RecruitingNCT07191834
What this trial is testing

A Study on the Short - Course Treatment Regimen Containing Pretomanid for Diabetes Mellitus Complicated With Rifampicin - Resistant/Multidrug - Resistant Pulmonary Tuberculosis

Who this might be right for
Rifampicin-resistant/Multidrug-resistant Pulmonary TuberculosisType 2 Diabetes Mellitus (T2DM)Pretomanid
Wuhan Pulmonary Hospital 60
Large-scale testing (Phase 3)Study completedNCT02342886
What this trial is testing

Shortening Treatment by Advancing Novel Drugs

Who this might be right for
Tuberculosis, Pulmonary, Drug SensitiveTuberculosis, Pulmonary, Multi Drug-resistant
Global Alliance for TB Drug Development 284
Large-scale testing (Phase 3)Study completedNCT02589782
What this trial is testing

Pragmatic Clinical Trial for a More Effective Concise and Less Toxic MDR-TB Treatment Regimen(s)

Who this might be right for
Tuberculosis, Multidrug-ResistantExtensively Drug-Resistant TuberculosisTuberculosis, Pulmonary
Medecins Sans Frontieres, Netherlands 552
Large-scale testing (Phase 3)Looking for participantsNCT07209761
What this trial is testing

Quabodepistat-containing Regimens for the Treatment of Drug-resistant Pulmonary Tuberculosis

Who this might be right for
Pulmonary Tuberculosis
Otsuka Pharmaceutical Development & Commercialization, Inc. 532
Early research (Phase 1)Study completedNCT01768273
What this trial is testing

Evaluation of the Pharmacokinetic Interaction Between PA-824 and Midazolam

Who this might be right for
Tuberculosis
Global Alliance for TB Drug Development 14
Testing effectiveness (Phase 2)Study completedNCT04179500
What this trial is testing

A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Pulmonary Tuberculosis

Who this might be right for
Tuberculosis, PulmonaryTuberculosis, Multidrug-ResistantTuberculosis, MDR+2 more
Global Alliance for TB Drug Development 26
Not applicableStudy completedNCT05609552
What this trial is testing

Biodistribution and Pharmacokinetics of Pretomanid in Tuberculosis Patients Using 18F-Pretomanid PET

Who this might be right for
Tuberculosis
Johns Hopkins University 10
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