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Results for “Primary Mitochondrial Disease”

61 trials

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Showing 20 of 61 results

Not applicableStudy completedNCT03917212
What this trial is testing

Energy Metabolism in Branched-chain Organic Acidemias

Who this might be right for
Energy MetabolismMetabolic SyndromeInsulin Resistance
German Diabetes Center 57
Large-scale testing (Phase 3)Ended earlyNCT03323749
What this trial is testing

A Trial to Evaluate Safety and Efficacy of Elamipretide Primary Mitochondrial Myopathy Followed by Open-Label Extension

Who this might be right for
Primary Mitochondrial Myopathy
Stealth BioTherapeutics Inc. 218
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Testing effectiveness (Phase 2)Ended earlyNCT02976038
What this trial is testing

Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mitochondrial Myopathy (PMM)

Who this might be right for
Primary Mitochondrial Disease
Stealth BioTherapeutics Inc. 28
Not applicableWithdrawnNCT05277363
What this trial is testing

The Natural Course of SURF1 Deficiency

Who this might be right for
Leigh Syndrome
Taysha Gene Therapies, Inc.
Not applicableEnrolling By InvitationNCT04734626
What this trial is testing

CrCest Study in Primary Mitochondrial Disease

Who this might be right for
Mitochondrial Diseases
Children's Hospital of Philadelphia 230
Early research (Phase 1)WithdrawnNCT04548843
What this trial is testing

A First in Human Study to Evaluate the Safety of Infusion of MNV-BM-PLC (Autologous CD34+ Cells Enriched With Placenta Derived Allogeneic Mitochondria) in Patients With Primary Mitochondrial Diseases Associated With Mitochondrial DNA Mutation or Deletion

Who this might be right for
Primary Mitochondrial Diseases
Minovia Therapeutics Ltd.
Not applicableLooking for participantsNCT05250375
What this trial is testing

Natural History Study of Mitochondrial Myopathy

Who this might be right for
Primary Mitochondrial Disease
Children's Hospital of Philadelphia 1,300
Not applicableUnknownNCT01298375
What this trial is testing

Metabolic Phenotyping in Humans

Who this might be right for
HealthyObesityType 2 Diabetes Mellitus
Maastricht University Medical Center 132
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07514338
What this trial is testing

Open Label Extension to Assess Long Term Safety and Efficacy of KL1333 in Patients With Primary Mitochondrial Disease

Who this might be right for
Mitochondrial Diseases
Pharming Technologies B.V. 140
Large-scale testing (Phase 3)Looking for participantsNCT04151472
What this trial is testing

Idebenone for the Preventive Treatment of Migraine

Who this might be right for
Migraine DisordersHeadache Disorders
Second Affiliated Hospital, School of Medicine, Zhejiang University 180
Post-approval studies (Phase 4)UnknownNCT05411978
What this trial is testing

Safety and Efficacy of Oral Idebenone for Preventive Treatment of Migraine in Adult Migraine Patients

Who this might be right for
Migraine
Beijing Tiantan Hospital 900
Not applicableLooking for participantsNCT07205874
What this trial is testing

Early Diagnosis of Primary Biliary Cholangitis (PBC) in Patients With Positive Anti-Mitochondrial Antibodies (AMA) and Normal Alkaline Phosphatase (ALP)

Who this might be right for
Primary Biliary Cholangitis (PBC)
Hospital Universitario La Paz 80
Not applicableStudy completedNCT03048617
What this trial is testing

An Observational Study of Patients With Primary Mitochondrial Disease (SPIMM-300)

Who this might be right for
Primary Mitochondrial Disease
Stealth BioTherapeutics Inc. 215
Not applicableLooking for participantsNCT06065852
What this trial is testing

National Registry of Rare Kidney Diseases

Who this might be right for
Adenine Phosphoribosyltransferase DeficiencyAH AmyloidosisAHL Amyloidosis+81 more
UK Kidney Association 35,000
Not applicableLooking for participantsNCT06167135
What this trial is testing

Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort

Who this might be right for
Infertility, FemalePolycystic Ovary SyndromeInsulin Resistance+3 more
Semmelweis University 150
Not applicableStudy completedNCT02284334
What this trial is testing

Glycemic Index in Mitochondrial Disease

Who this might be right for
Mitochondrial Diseases
Children's Hospital of Philadelphia 18
Not applicableUnknownNCT05910151
What this trial is testing

Selective Screening of Children for Hereditary Metabolic Diseases by Tandem Mass Spectrometry in Kazakhstan

Who this might be right for
Propionic/Methylmalonic AcidemiasMaple Syrup Urine DiseaseCitrullinemia+26 more
West Kazakhstan Medical University 2,250
Not applicableStudy completedNCT00626847
What this trial is testing

How Does Your Genetic Make-up (Profile) Influence Your Glaucoma?

Who this might be right for
Primary Open Angle Glaucoma
Wills Eye 97
Testing effectiveness (Phase 2)Study completedNCT05972954
What this trial is testing

OMT-28 in Patients With Primary Mitochondrial Disease (PMD) (PMD-OPTION)

Who this might be right for
Primary Mitochondrial Disease
Omeicos Therapeutics GmbH 28
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