Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Primary Mitochondrial Disease”

62 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 62 results

Testing effectiveness (Phase 2)Study completedNCT04513002
What this trial is testing

Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With a Novel Form of Anaplerosis

Who this might be right for
Ataxia Telangiectasia
The University of Queensland 30
Not applicableUnknownNCT06324877
What this trial is testing

Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide Riboside

Who this might be right for
Ataxia Telangiectasia
The University of Queensland 10
Testing effectiveness (Phase 2)Study completedNCT02805790
What this trial is testing

Safety, Tolerability, Efficacy of MTP-131 for Treatment of Mitochondrial Disease in Subjects From the MMPOWER Study

Who this might be right for
Primary Mitochondrial Disease
Stealth BioTherapeutics Inc. 30
Not applicableStudy completedNCT05017818
What this trial is testing

A Retrospective Study of Subjects With Thymidine Kinase 2 Deficiency

Who this might be right for
Thymidine Kinase 2 Deficiency
Zogenix MDS, Inc. 61
Early research (Phase 1)Looking for participantsNCT06340685
What this trial is testing

Triheptanoin for Children With Primary-Specific Pyruvate Dehydrogenase Complex (PDC) Deficiency

Who this might be right for
Pyruvate Dehydrogenase Complex Deficiency
Jirair Krikor Bedoyan 6
Not applicableLooking for participantsNCT06474104
What this trial is testing

Collection of Blood and Skin Samples From Patients With Primary Mitochondrial Diseases and Healthy Volunteers

Who this might be right for
Primary Mitochondrial Diseases
Minovia Therapeutics Ltd. 100
Testing effectiveness (Phase 2)Study completedNCT02367014
What this trial is testing

Safety, Tolerability, and Efficacy of MTP-131 for the Treatment of Mitochondrial Myopathy

Who this might be right for
Mitochondrial Myopathy
Stealth BioTherapeutics Inc. 36
Early research (Phase 1)Study completedNCT03888716
What this trial is testing

A Phase Ia/Ib, SAD and MAD Study of of KL1333 in Healthy Subjects and Patients With Primary Mitochondrial Disease

Who this might be right for
Mitochondrial DiseasesMitochondrial Respiratory Chain DeficienciesMELAS Syndrome+1 more
Abliva AB 72
Not applicableStudy completedNCT03120013
What this trial is testing

Rehabilitative Trial With Cerebello-Spinal tDCS in Neurodegenerative Ataxia

Who this might be right for
Ataxia, CerebellarCerebellar AtaxiaSpinocerebellar Ataxias+8 more
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 21
Not applicableStudy completedNCT00727974
What this trial is testing

Genetic Analysis of Children With Cyclic Vomiting Syndrome (CVS) and Migraines

Who this might be right for
VomitingMigraines
Medical College of Wisconsin 586
Not applicableStudy completedNCT00804102
What this trial is testing

Transcorneal Electrical Stimulation Therapy for Retinal Disease

Who this might be right for
Retinitis PigmentosaMacula OffPrimary Open Angle Glaucoma+8 more
Okuvision GmbH 80
Testing effectiveness (Phase 2)Study completedNCT03845712
What this trial is testing

An Open-Label Study of Continuation Treatment With Combination Pyrimidine Nucleosides in Patients With TK2 Deficiency

Who this might be right for
Thymidine Kinase 2 Deficiency
UCB BIOSCIENCES, Inc. 47
Testing effectiveness (Phase 2)Looking for participantsNCT07514338
What this trial is testing

Open Label Extension to Assess Long Term Safety and Efficacy of KL1333 in Patients With Primary Mitochondrial Disease

Who this might be right for
Mitochondrial Diseases
Pharming Technologies B.V. 140
Not applicableStudy completedNCT03979482
What this trial is testing

Skeletal Muscle Mitochondrial Abnormalities and the Metabolic Syndrome in PAH

Who this might be right for
Pulmonary Artery Hypertension
Laval University 30
Not applicableStudy completedNCT03048617
What this trial is testing

An Observational Study of Patients With Primary Mitochondrial Disease (SPIMM-300)

Who this might be right for
Primary Mitochondrial Disease
Stealth BioTherapeutics Inc. 215
Early research (Phase 1)Looking for participantsNCT05569122
What this trial is testing

Applying pGz in Mitochondrial Disease

Who this might be right for
Mitochondrial MyopathiesMitochondrial Diseases
Children's Hospital of Philadelphia 90
Post-approval studies (Phase 4)UnknownNCT05411978
What this trial is testing

Safety and Efficacy of Oral Idebenone for Preventive Treatment of Migraine in Adult Migraine Patients

Who this might be right for
Migraine
Beijing Tiantan Hospital 900
Testing effectiveness (Phase 2)Looking for participantsNCT06754098
What this trial is testing

Doxecitin and Doxribthymine in Adult Subjects With Thymidine Kinase 2 (TK2) Deficiency

Who this might be right for
Thymidine Kinase 2 (TK2 ) DeficiencyMitochondrial Myopathies
Cristina Domínguez González 15
Not applicableStudy completedNCT02920671
What this trial is testing

Muscle OXPHOS and Nutrient Homeostasis

Who this might be right for
Mitochondrial DiseasesObesity
University of Pennsylvania 45
Early research (Phase 1)Study completedNCT00001328
What this trial is testing

Gene Therapy for the Treatment of Brain Tumors

Who this might be right for
Brain NeoplasmNeoplasm Metastasis
National Institute of Neurological Disorders and Stroke (NINDS) 15
Next Page