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Results for “Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT07468630
What this trial is testing

Tolecizumab Plus Chemoimmunotherapy for pMMR/MSS Locally Advanced Colon Adenocarcinoma

Who this might be right for
Colon Adenocarcinoma
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 106
Testing effectiveness (Phase 2)Study completedNCT03933293
What this trial is testing

Evaluate the Safety and Efficacy of the PCSK9 Inhibitor AK102 in Patients With HoFH

Who this might be right for
Homozygous Familial Hypercholesterolemia
Akeso 10
Post-approval studies (Phase 4)Looking for participantsNCT04731155
What this trial is testing

Impact of Early PCSK9 Inhibitor on Heart After Acute Myocardium Infarction

Who this might be right for
Early PCSK9 Inhibitor on Ventricular Remodling
Shanghai Tong Ren Hospital 20
Testing effectiveness (Phase 2)Study completedNCT07301372
What this trial is testing

Evaluation Study of Early Administration of Evolocumab After Thrombolysis in Patients With Atherosclerotic Acute Ischemic Stroke

Who this might be right for
Acute Stroke
The Affiliated Hospital of Xuzhou Medical University 132
Early research (Phase 1)Study completedNCT05934292
What this trial is testing

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Renal Impairment Study (MK-0616-020)

Who this might be right for
Hypercholesterolaemia
Merck Sharp & Dohme LLC 33
Large-scale testing (Phase 3)UnknownNCT04806893
What this trial is testing

Study of Long-Term Efficacy and Safety of LIB003 in CVD or High Risk for CVD Patients Needing Further LDL-C Reduction

Who this might be right for
Cardiovascular Risk FactorCardiovascular DiseasesCardiovascular Stroke+1 more
LIB Therapeutics LLC 900
Post-approval studies (Phase 4)Study completedNCT07295366
What this trial is testing

Early Administration of PCSK9 Inhibitors After Thrombectomy for Atherosclerotic Acute Ischemic Stroke: A Randomized Controlled Trial

Who this might be right for
Acute Stroke
The Affiliated Hospital of Xuzhou Medical University 60
Large-scale testing (Phase 3)UnknownNCT04797247
What this trial is testing

Study of Efficacy and Safety of LIB003 in Patient With CVD on Statins Requiring Additional LDL-C Reduction

Who this might be right for
Cardiovascular DiseasesHyper-LDL-cholesterolemia
LIB Therapeutics LLC 900
Not applicableLooking for participantsNCT07036991
What this trial is testing

A Cohort Study Comparing PCSK9 Inhibitor Plus Statin With Statin Monotherapy for Carotid Artery Stenosis

Who this might be right for
Carotid Artery Stenosis
Changhai Hospital 406
Not applicableLooking for participantsNCT07208006
What this trial is testing

Very Early PCSK9 Inhibition for Acute Myocardial Infarction

Who this might be right for
Acute Myocardial Infarction (AMI)
Shanghai Zhongshan Hospital 1,518
Large-scale testing (Phase 3)Study completedNCT05888103
What this trial is testing

Efficacy and Safety of Inclisiran as Monotherapy in Chinese Adults With Low or Moderate ASCVD Risk and Elevated Low-density Lipoprotein Cholesterol.

Who this might be right for
Primary Hypercholesterolemia or Mixed Dyslipidemia
Novartis Pharmaceuticals 207
Post-approval studies (Phase 4)Not Yet RecruitingNCT07466251
What this trial is testing

PCSK9 Inhibitor for Intracranial Atherosclerosis Related Acute Ischemic Stroke

Who this might be right for
Acute Ischemic Stroke AISIntracranial Atherosclerosis ICASAtherosclerotic Plaque
Peking Union Medical College Hospital 1,212
Large-scale testing (Phase 3)Study completedNCT04797104
What this trial is testing

Study to Assess the Efficacy and Safety of LIB003 in HeFH Patients on Oral Lipid Therapy Needing Further LDL-C Reduction

Who this might be right for
Heterozygous Familial Hypercholesterolemia
LIB Therapeutics LLC 478
Large-scale testing (Phase 3)Study completedNCT04941105
What this trial is testing

Impact of PCSK9 Inhibition on Clinical Outcome in Patients During the Inflammatory Stage of the COVID-19

Who this might be right for
Sars-CoV-2 Infection
Collegium Medicum w Bydgoszczy 60
Large-scale testing (Phase 3)Study completedNCT05952869
What this trial is testing

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017/CORALreef HeFH)

Who this might be right for
HypercholesterolemiaFamilial Hypercholesterolemia
Merck Sharp & Dohme LLC 303
Not applicableLooking for participantsNCT05765370
What this trial is testing

LDL Cholesterol TARGETs in OLDer Patients (Age≥75 Years) With ASCVD (TARGET OLD)

Who this might be right for
Atherosclerotic Cardiovascular DiseaseOlder PatientsLDL Cholesterol
China National Center for Cardiovascular Diseases 4,200
Post-approval studies (Phase 4)UnknownNCT05802108
What this trial is testing

Effect of PCSK9 Inhibitor on Retinal Microvessels in Patients With Coronary Heart Disease After Intensive Lipid-lowering Therapy

Who this might be right for
Adverse Effect of Cardiovascular Medications (Diagnosis)
Zibo Central Hospital 60
Post-approval studies (Phase 4)Looking for participantsNCT06902740
What this trial is testing

PCSK9 Inhibitor With Statin Therapy for Asymptomatic Intracranial Atherosclerosis

Who this might be right for
Intracranial AtherosclerosisIntracranial Artery StenosisAtherosclerotic Plaque
Peking Union Medical College Hospital 300
Early research (Phase 1)Study completedNCT03366688
What this trial is testing

Single Ascending Dose Study of PCSK-9 Inhibitor (IBI306) in Healthy Subjects.

Who this might be right for
Hypercholesterolemia
Innovent Biologics (Suzhou) Co. Ltd. 58
Large-scale testing (Phase 3)Active Not RecruitingNCT06492291
What this trial is testing

Open-label Extension Study of Enlicitide Decanoate (MK-0616/Enlicitide Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-019) CORALreef Extension

Who this might be right for
Hypercholesterolemia
Merck Sharp & Dohme LLC 3,000
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