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Results for “Protein Kinase Inhibitors”

110 trials

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Showing 20 of 110 results

Testing effectiveness (Phase 2)Ended earlyNCT02943473
What this trial is testing

Study on the Effect of Ibrutinib on High Risk Smoldering Multiple Myeloma Patients

Who this might be right for
High Risk Smoldering Multiple Myeloma
Icahn School of Medicine at Mount Sinai 9
Early research (Phase 1)Study completedNCT01353625
What this trial is testing

Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies.

Who this might be right for
Glioblastoma MultiformeSquamous Cell Carcinoma of Head and NeckProstate Cancer+3 more
Celgene 118
Not applicableUnknownNCT03571438
What this trial is testing

Evaluation of a Promising New Combination of Protein Kinase Inhibitors on Organotypic Cultures of Human Renal Tumors

Who this might be right for
Kidney Cancer
University Hospital, Grenoble 100
Early research (Phase 1)Study completedNCT01585701
What this trial is testing

Phase I Study of AT13148, a Novel AGC Kinase Inhibitor

Who this might be right for
Advanced Solid Tumours
Cancer Research UK 56
Testing effectiveness (Phase 2)Study completedNCT00511303
What this trial is testing

Protein-Tyrosine Kinase Inhibitor (STI571) for Treatment of Patients With Ph+ Chronic Myeloid Leukemia

Who this might be right for
Chronic Myeloid Leukemia
University of Bologna 200
Testing effectiveness (Phase 2)UnknownNCT01764087
What this trial is testing

KX2-391 With Paclitaxel in Patients With Solid Tumors

Who this might be right for
Unspecified Adult Solid Tumor, Protocol SpecificGastric CancerBreast Cancer
Hanmi Pharmaceutical Company Limited 60
Early research (Phase 1)Looking for participantsNCT06717750
What this trial is testing

CSCJC3456 in Patients With Advanced Malignant Tumors

Who this might be right for
Advanced Malignant Solid Tumors
Changshan ConjuChem BioPharmaceutical Research and Development (Hebei) Co., Ltd. 102
Early research (Phase 1)Study completedNCT00676299
What this trial is testing

A Safety and Dose-finding Study of JNJ-26483327, a Drug in Development for Cancer, for Patients With Advanced and/or Refractory Solid Malignancies.

Who this might be right for
Protein Kinase InhibitorsAntineoplastic ProtocolsClinical Trial, Phase 1+4 more
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 19
Early research (Phase 1)Study completedNCT00443976
What this trial is testing

Aurora Kinase Inhibitor AT9283 in Treating Patients With Advanced or Metastatic Solid Tumors or Non-Hodgkin's Lymphoma

Who this might be right for
Non-Hodgkins LymphomaUnspecified Adult Solid Tumor, Protocol Specific
NCIC Clinical Trials Group 35
Not applicableLooking for participantsNCT06151730
What this trial is testing

Evaluation of Hypertension Management and Cardiovascular Adverse Event Prevention in Patients With B-cell Malignancies Undergoing Treatment With Bruton Tyrosine Kinase Inhibitors, the HALT Study

Who this might be right for
Chronic Lymphocytic LeukemiaHematopoietic and Lymphoid System NeoplasmMantle Cell Lymphoma+2 more
Mayo Clinic 100
Testing effectiveness (Phase 2)UnknownNCT04933799
What this trial is testing

IRAK 4 Inhibitor (PF-06650833) in Hospitalized Patients With COVID-19 Pneumonia and Exuberant Inflammation.

Who this might be right for
COVID-19 Pneumonia
Giovanni Franchin, M.D, Ph.D 68
Early research (Phase 1)Study completedNCT00446342
What this trial is testing

Study of Intravenously Administered SNS-032 in Patients With Advanced B-lymphoid Malignancies

Who this might be right for
B-lymphoid MalignanciesChronic Lymphocytic LeukemiaMantle Cell Lymphoma+1 more
Sunesis Pharmaceuticals 21
Large-scale testing (Phase 3)Looking for participantsNCT05770037
What this trial is testing

DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers

Who this might be right for
Haematological MalignancyMalignant NeoplasmLymphoproliferative Disorders+8 more
Cancer Research UK 30
Early research (Phase 1)Study completedNCT00697346
What this trial is testing

Study of MLN8237 in Participants With Advanced Hematological Malignancies

Who this might be right for
B-cell Follicular LymphomaB-cell Marginal Zone LymphomaDiffuse Large B-cell Lymphoma+10 more
Millennium Pharmaceuticals, Inc. 58
Testing effectiveness (Phase 2)Study completedNCT01467986
What this trial is testing

Multimodal Molecular Targeted Therapy to Treat Relapsed or Refractory High-risk Neuroblastoma

Who this might be right for
Neuroblastoma Recurrent
University of Regensburg 130
Large-scale testing (Phase 3)Looking for participantsNCT01804686
What this trial is testing

A Long-term Extension Study of PCI-32765 (Ibrutinib)

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic LymphomaMantle Cell Lymphoma+4 more
Janssen Research & Development, LLC 700
Not applicableLooking for participantsNCT01281735
What this trial is testing

International Chronic Myeloid Leukemia Pediatric Study

Who this might be right for
Chronic Myeloid Leukemia
Poitiers University Hospital 750
Large-scale testing (Phase 3)Looking for participantsNCT07185997
What this trial is testing

Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

Who this might be right for
Non-Small-Cell Lung CancerMetastatic Non-Small-Cell Lung CancerAdvanced Non-Small-Cell Lung Cancer+3 more
ArriVent BioPharma, Inc.
Large-scale testing (Phase 3)Study completedNCT03053440
What this trial is testing

A Study Comparing BGB-3111 and Ibrutinib in Participants With Waldenström's Macroglobulinemia (WM)

Who this might be right for
Waldenström's Macroglobulinemia
BeiGene 201
Testing effectiveness (Phase 2)Study completedNCT04997850
What this trial is testing

The Safety and Efficacy of Transarterial Chemoembolization (TACE) + Lenvatinib + Programmed Cell Death Protein 1 (PD-1) Antibody of Advanced Unresectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma Non-resectableTransarterial ChemoembolizationTyrosine Kinase Inhibitor+1 more
Xinrui Zhu，MD 142
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