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Results for “Protein Kinase Inhibitors”

108 trials

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Showing 20 of 108 results

Early research (Phase 1)Study completedNCT02211014
What this trial is testing

An Open-Label, Phase 1b Study of Acalabrutinib With and Without Dexamethasone in Subjects With Multiple Myeloma

Who this might be right for
Multiple Myeloma (MM)
Acerta Pharma BV 27
Early research (Phase 1)Study completedNCT01585701
What this trial is testing

Phase I Study of AT13148, a Novel AGC Kinase Inhibitor

Who this might be right for
Advanced Solid Tumours
Cancer Research UK 56
Large-scale testing (Phase 3)Study completedNCT01535391
What this trial is testing

Nilotinib in PH+, BCR-, ABL+ CML Patients

Who this might be right for
Chronic Myeloid Leukemia
Gruppo Italiano Malattie EMatologiche dell'Adulto 109
Early research (Phase 1)Ended earlyNCT05153408
What this trial is testing

(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC

Who this might be right for
Lung NeoplasmCarcinoma, Non-Small-Cell LungRespiratory Tract Neoplasms+24 more
Blueprint Medicines Corporation 20
Early research (Phase 1)Study completedNCT04712396
What this trial is testing

Assess How Itraconazole Affects the Uptake and Elimination of Capivasertib in the Body

Who this might be right for
Healthy Volunteers (Intended Indication: Metastatic Patients With Triple Negative or HR+ Breast Cancer, or Hormone Sensitive Prostate Cancer)
AstraZeneca 11
Not applicableStudy completedNCT02824159
What this trial is testing

Association Between Side Effects Occurrence and Concentrations of Ibrutinib and Idelalisib

Who this might be right for
Hematological Malignancies
University Hospital, Toulouse 121
Testing effectiveness (Phase 2)Study completedNCT01229150
What this trial is testing

Randomized Phase II Study of AZD6244 (Mitogen-activated Protein Kinase Inhibitor) MEK-Inhibitor With Erlotinib in KRAS Wild Type Advanced Non-Small Cell Lung Cancer (NSCLC) and a Randomized Phase II Study of AZD6244 With Erlotinib in Mutant KRAS Adva...

Who this might be right for
Non Small Cell Lung Carcinoma
National Cancer Institute (NCI) 89
Large-scale testing (Phase 3)Looking for participantsNCT06846671
What this trial is testing

BGB-16673 Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors

Who this might be right for
CLLChronic Lymphocytic Leukemia
BeOne Medicines 250
Testing effectiveness (Phase 2)Study completedNCT02362035
What this trial is testing

ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies

Who this might be right for
Follicular Lymphoma (FL)CLLSmall Lymphocytic Lymphoma (SLL)+10 more
Acerta Pharma BV 161
Not applicableUnknownNCT03571438
What this trial is testing

Evaluation of a Promising New Combination of Protein Kinase Inhibitors on Organotypic Cultures of Human Renal Tumors

Who this might be right for
Kidney Cancer
University Hospital, Grenoble 100
Early research (Phase 1)Ended earlyNCT04862780
What this trial is testing

(SYMPHONY) Phase 1/2 Study Targeting EGFR Resistance Mechanisms in NSCLC

Who this might be right for
Lung NeoplasmsCarcinoma, Non-Small-Cell LungRespiratory Tract Neoplasms+21 more
Blueprint Medicines Corporation 177
Early research (Phase 1)Study completedNCT00697346
What this trial is testing

Study of MLN8237 in Participants With Advanced Hematological Malignancies

Who this might be right for
B-cell Follicular LymphomaB-cell Marginal Zone LymphomaDiffuse Large B-cell Lymphoma+10 more
Millennium Pharmaceuticals, Inc. 58
Not applicableEnded earlyNCT02455024
What this trial is testing

An Observational Registry to Evaluate the Incidence of and Risk Factors for Vascular Occlusive Events Associated With ICLUSIG®

Who this might be right for
Myeloid Leukemia, Chronic-Phase, Accelerated-Phase, Blast-Phase, Ph+ALL
Ariad Pharmaceuticals 3
Not applicableLooking for participantsNCT06535568
What this trial is testing

Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO IV-EPIC 38)

Who this might be right for
Coronary DiseaseHeart DiseasesCardiovascular Diseases+22 more
Fondazione Ricerca e Innovazione Cardiovascolare ETS 576
Testing effectiveness (Phase 2)Study completedNCT04518852
What this trial is testing

TACE, Sorafenib and PD-1 Monoclonal Antibody in the Treatment of HCC

Who this might be right for
Hepatocellular CarcinomaLiver NeoplasmsDigestive System Neoplasms+5 more
Sichuan Cancer Hospital and Research Institute 27
Testing effectiveness (Phase 2)Study completedNCT00005931
What this trial is testing

SU5416 in Patients With AIDS-Related Kaposi's Sarcoma Who Have Not Responded to Treatment

Who this might be right for
Sarcoma, KaposiHIV Infections
SUGEN 30
Large-scale testing (Phase 3)Looking for participantsNCT06988475
What this trial is testing

DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations

Who this might be right for
Solid TumourHaematological MalignancyMalignant Neoplasm+8 more
Cancer Research UK 30
Early research (Phase 1)Study completedNCT00725634
What this trial is testing

Dose-Escalation Study in Advanced Solid Tumors, Lymphomas or Multiple Myeloma

Who this might be right for
Malignant Solid TumorLymphomasMultiple Myeloma
AVEO Pharmaceuticals, Inc. 41
Early research (Phase 1)Study completedNCT00446342
What this trial is testing

Study of Intravenously Administered SNS-032 in Patients With Advanced B-lymphoid Malignancies

Who this might be right for
B-lymphoid MalignanciesChronic Lymphocytic LeukemiaMantle Cell Lymphoma+1 more
Sunesis Pharmaceuticals 21
Testing effectiveness (Phase 2)Study completedNCT00514969
What this trial is testing

Protein-Tyrosine Kinase Inhibitor (STI571) for Treatment of Patients With Ph+ Chronic Myeloid Leukemia in Accelerated and Blastic Phase

Who this might be right for
Chronic Myeloid Leukemia
University of Bologna
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