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Results for “Protein Kinase Inhibitors”

107 trials

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Showing 20 of 107 results

Testing effectiveness (Phase 2)Study completedNCT02596828
What this trial is testing

Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma

Who this might be right for
Pineoblastoma
University of Regensburg 4
Early research (Phase 1)Study completedNCT01594398
What this trial is testing

Study to Assess Food Effect on Pharmacokinetics of Entinostat in Subjects With Breast Cancer or Non-Small Cell Lung Cancer

Who this might be right for
Lung CancerNon Small Cell Lung Cancer (NSCLC)Breast Cancer+1 more
Syndax Pharmaceuticals 14
Large-scale testing (Phase 3)Study completedNCT01865747
What this trial is testing

Cabozantinib (XL184) vs Everolimus in Subjects With Metastatic Renal Cell Carcinoma

Who this might be right for
Renal Cell Carcinoma
Exelixis 658
Post-approval studies (Phase 4)Study completedNCT04562428
What this trial is testing

The Safety and Efficacy Evaluation of XSLJZ in Advanced Hepatocellular Carcinoma Patients With Multiple Protein Kinase Inhibitor Therapy: A Randomized, Double-Blind, Controlled Trial

Who this might be right for
Hepatocellular Carcinoma
China Medical University Hospital 10
Testing effectiveness (Phase 2)Study completedNCT01844765
What this trial is testing

Open Label, Phase II Study to Evaluate Efficacy and Safety of Oral Nilotinib in Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia (CML) Pediatric Patients.

Who this might be right for
Philadelphia Positive (Ph+) Chronic Myelogenous Leukemia
Novartis Pharmaceuticals 59
Early research (Phase 1)Study completedNCT02211014
What this trial is testing

An Open-Label, Phase 1b Study of Acalabrutinib With and Without Dexamethasone in Subjects With Multiple Myeloma

Who this might be right for
Multiple Myeloma (MM)
Acerta Pharma BV 27
Early research (Phase 1)Ended earlyNCT01288430
What this trial is testing

DS-2248 in Participants With Advanced Solid Tumors

Who this might be right for
Solid TumorsNon-small Cell Lung Carcinoma
Daiichi Sankyo 60
Not applicableEnded earlyNCT00504205
What this trial is testing

MP470 in Treating Patients With Unresectable or Metastatic Solid Tumor or Lymphoma

Who this might be right for
LymphomaUnspecified Adult Solid Tumor, Protocol Specific
Astex Pharmaceuticals, Inc. 30
Large-scale testing (Phase 3)Active Not RecruitingNCT01933932
What this trial is testing

Assess Efficacy & Safety of Selumetinib in Combination With Docetaxel in Patients Receiving 2nd Line Treatment for v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Positive NSCLC

Who this might be right for
Locally Advanced or Metastatic Non Small Cell Lung Cancer Stage IIIb - IV
AstraZeneca 510
Testing effectiveness (Phase 2)Study completedNCT04997850
What this trial is testing

The Safety and Efficacy of Transarterial Chemoembolization (TACE) + Lenvatinib + Programmed Cell Death Protein 1 (PD-1) Antibody of Advanced Unresectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma Non-resectableTransarterial ChemoembolizationTyrosine Kinase Inhibitor+1 more
Xinrui Zhu，MD 142
Not applicableLooking for participantsNCT01281735
What this trial is testing

International Chronic Myeloid Leukemia Pediatric Study

Who this might be right for
Chronic Myeloid Leukemia
Poitiers University Hospital 750
Not applicableLooking for participantsNCT04965129
What this trial is testing

Supplementation of n-3 PUFA in the Modulation of Lean Mass in Patients With Lung Cancer Receiving a High-protein Diet

Who this might be right for
Lung Cancer
Universidade Federal do Rio de Janeiro 50
Testing effectiveness (Phase 2)Study completedNCT00287105
What this trial is testing

Safety and Efficacy of Imatinib Added to Chemotherapy in Treatment of Ph+ Acute Lymphoblastic Leukemia in Children

Who this might be right for
Acute Lymphoblastic LeukemiaPhiladelphia Chromosome
Rennes University Hospital 49
Testing effectiveness (Phase 2)Ended earlyNCT04575610
What this trial is testing

IRAK4 Inhibition in Treatment of COVID-19 With ARDS (I-RAMIC)

Who this might be right for
COVID-19
Yale University 7
Early research (Phase 1)Study completedNCT02292173
What this trial is testing

Trametinib in Combination With Sorafenib in Patients With Advanced Hepatocellular Cancer

Who this might be right for
Hepatocellular CancerLiver Cancer
H. Lee Moffitt Cancer Center and Research Institute 17
Early research (Phase 1)Study completedNCT00676299
What this trial is testing

A Safety and Dose-finding Study of JNJ-26483327, a Drug in Development for Cancer, for Patients With Advanced and/or Refractory Solid Malignancies.

Who this might be right for
Protein Kinase InhibitorsAntineoplastic ProtocolsClinical Trial, Phase 1+4 more
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 19
Not applicableLooking for participantsNCT06151730
What this trial is testing

Evaluation of Hypertension Management and Cardiovascular Adverse Event Prevention in Patients With B-cell Malignancies Undergoing Treatment With Bruton Tyrosine Kinase Inhibitors, the HALT Study

Who this might be right for
Chronic Lymphocytic LeukemiaHematopoietic and Lymphoid System NeoplasmMantle Cell Lymphoma+2 more
Mayo Clinic 100
Large-scale testing (Phase 3)Looking for participantsNCT06973187
What this trial is testing

Evaluate the Safety and Efficacy of BGB-16673 Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
BeOne Medicines 500
Testing effectiveness (Phase 2)Ended earlyNCT02757326
What this trial is testing

ABC294640 (Opaganib) in Refractory / Relapsed Multiple Myeloma

Who this might be right for
Multiple Myeloma
RedHill Biopharma Limited 13
Large-scale testing (Phase 3)Looking for participantsNCT05722886
What this trial is testing

DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol

Who this might be right for
Haematological MalignancySolid Tumour
Cancer Research UK 825
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