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Results for “Protein Kinase Inhibitors”

110 trials

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Showing 20 of 110 results

Testing effectiveness (Phase 2)UnknownNCT02340845
What this trial is testing

Bromelain, Comosain as a New Drug for Treating and Preventing Various Types of Cancer in the Humans

Who this might be right for
Cancer
Oeyama-Moto Cancer Research Foundation 100
Early research (Phase 1)Ended earlyNCT05241873
What this trial is testing

(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations

Who this might be right for
Lung Neoplasm MalignantCarcinoma, Non-Small-Cell LungRespiratory Tract Neoplasms+17 more
Blueprint Medicines Corporation 103
Testing effectiveness (Phase 2)Study completedNCT01229150
What this trial is testing

Randomized Phase II Study of AZD6244 (Mitogen-activated Protein Kinase Inhibitor) MEK-Inhibitor With Erlotinib in KRAS Wild Type Advanced Non-Small Cell Lung Cancer (NSCLC) and a Randomized Phase II Study of AZD6244 With Erlotinib in Mutant KRAS Adva...

Who this might be right for
Non Small Cell Lung Carcinoma
National Cancer Institute (NCI) 89
Testing effectiveness (Phase 2)Ended earlyNCT04305444
What this trial is testing

Study of a Triple Combination Therapy, DTRM-555, in Patients With R/R CLL or R/R Non-Hodgkin's Lymphomas

Who this might be right for
Relapsed Chronic Lymphocytic LeukemiaRefractory Chronic Lymphocytic LeukemiaDiffuse Large B Cell Lymphoma+2 more
Zhejiang DTRM Biopharma 55
Large-scale testing (Phase 3)Study completedNCT03053440
What this trial is testing

A Study Comparing BGB-3111 and Ibrutinib in Participants With Waldenström's Macroglobulinemia (WM)

Who this might be right for
Waldenström's Macroglobulinemia
BeiGene 201
Testing effectiveness (Phase 2)Study completedNCT01039948
What this trial is testing

A Phase 1b/2 Study in Asian Subjects With Non-Small Cell Lung Cancer

Who this might be right for
Carcinoma, Non-Small Cell-LungLung NeoplasmsLung Cancer+1 more
AVEO Pharmaceuticals, Inc. 203
Not applicableStudy completedNCT03916458
What this trial is testing

REGISTRY OF COMPLETE RESPONSES TO SUNITINIB IN SPANISH PATIENTS WITH METASTATIC RENAL CELL CARCINOMA

Who this might be right for
Carcinoma, Renal Cell
Pfizer 62
Early research (Phase 1)Study completedNCT00574366
What this trial is testing

Erlotinib and Everolimus in Treating Patients With Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Vanderbilt-Ingram Cancer Center 14
Large-scale testing (Phase 3)Looking for participantsNCT05722886
What this trial is testing

DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol

Who this might be right for
Haematological MalignancySolid Tumour
Cancer Research UK 825
Testing effectiveness (Phase 2)Study completedNCT00287105
What this trial is testing

Safety and Efficacy of Imatinib Added to Chemotherapy in Treatment of Ph+ Acute Lymphoblastic Leukemia in Children

Who this might be right for
Acute Lymphoblastic LeukemiaPhiladelphia Chromosome
Rennes University Hospital 49
Early research (Phase 1)Study completedNCT02292173
What this trial is testing

Trametinib in Combination With Sorafenib in Patients With Advanced Hepatocellular Cancer

Who this might be right for
Hepatocellular CancerLiver Cancer
H. Lee Moffitt Cancer Center and Research Institute 17
Testing effectiveness (Phase 2)Study completedNCT04518852
What this trial is testing

TACE, Sorafenib and PD-1 Monoclonal Antibody in the Treatment of HCC

Who this might be right for
Hepatocellular CarcinomaLiver NeoplasmsDigestive System Neoplasms+5 more
Sichuan Cancer Hospital and Research Institute 27
Post-approval studies (Phase 4)Study completedNCT04562428
What this trial is testing

The Safety and Efficacy Evaluation of XSLJZ in Advanced Hepatocellular Carcinoma Patients With Multiple Protein Kinase Inhibitor Therapy: A Randomized, Double-Blind, Controlled Trial

Who this might be right for
Hepatocellular Carcinoma
China Medical University Hospital 10
Testing effectiveness (Phase 2)Study completedNCT04116437
What this trial is testing

Zanubrutinib (BGB-3111) in Participants With Previously Treated B-Cell Lymphoma Intolerant of Prior Bruton Tyrosine Kinase Inhibitor (BTKi) Treatment

Who this might be right for
Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaMantle Cell LymphomaMarginal Zone Lymphoma+1 more
BeiGene 96
Large-scale testing (Phase 3)Looking for participantsNCT07440290
What this trial is testing

DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers.

Who this might be right for
Haematological MalignancyMalignant NeoplasmLymphoproliferative Disorders+17 more
Cancer Research UK 30
Testing effectiveness (Phase 2)Ended earlyNCT04575610
What this trial is testing

IRAK4 Inhibition in Treatment of COVID-19 With ARDS (I-RAMIC)

Who this might be right for
COVID-19
Yale University 7
Testing effectiveness (Phase 2)UnknownNCT04483219
What this trial is testing

Tyrosine Kinase Inhibitor (TKI) + Anti-PD-1 Antibody in TKI-responded Microsatellite Stability/Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Adenocarcinoma.

Who this might be right for
MSSpMMRMetastatic Colorectal Adenocarcinoma
China Medical University, China 53
Early research (Phase 1)Study completedNCT02211014
What this trial is testing

An Open-Label, Phase 1b Study of Acalabrutinib With and Without Dexamethasone in Subjects With Multiple Myeloma

Who this might be right for
Multiple Myeloma (MM)
Acerta Pharma BV 27
Testing effectiveness (Phase 2)Study completedNCT00481052
What this trial is testing

Nilotinib as First-line Treatment of Ph+ CML in Early Chronic Phase

Who this might be right for
Chronic Myeloid Leukemia
Gruppo Italiano Malattie EMatologiche dell'Adulto 74
Early research (Phase 1)Study completedNCT05002140
What this trial is testing

Trial of XRD-0394, a Kinase Inhibitor, in Combination With Palliative Radiotherapy in Advanced Cancer Patients

Who this might be right for
MetastasisLocally Advanced Solid TumorRecurrent Cancer
XRad Therapeutics Inc 12
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