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Results for “Pulmonary Emphysema in Alpha-1 Antitrypsin Deficiency”

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Showing 20 of 0 results

Not applicableStudy completedNCT03804021
What this trial is testing

Long-Term Follow-up Study of ADVM-043

Who this might be right for
Alpha-1 Antitrypsin Deficiency
Adverum Biotechnologies, Inc. 6
Testing effectiveness (Phase 2)Ended earlyNCT04764448
What this trial is testing

Belcesiran in Patients With AATLD

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company 16
Post-approval studies (Phase 4)Study completedNCT00670007
What this trial is testing

Extension Study of Zemaira® i.v. Administration in Subjects With Emphysema Due to alpha1-proteinase Inhibitor Deficiency.

Who this might be right for
EmphysemaAlpha 1-proteinase Inhibitor Deficiency
CSL Behring 140
Early research (Phase 1)Study completedNCT03362242
What this trial is testing

Study of ARO-AAT in Normal Adult Volunteers

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Arrowhead Pharmaceuticals 45
Not applicableStudy completedNCT01676688
What this trial is testing

Safety Study of Alfalastin (Human Alpha-1 Antitrypsin) Administered at Home

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Laboratoire français de Fractionnement et de Biotechnologies 17
Testing effectiveness (Phase 2)Study completedNCT03114020
What this trial is testing

Efficacy/Safety of HA Inhalation Solution for Hereditary Emphysema in Patients With Alpha-1 Antitrypsin Deficiency

Who this might be right for
EmphysemaAlpha 1-Antitrypsin Deficiency
Gerard Turino 27
Not applicableLooking for participantsNCT00001532
What this trial is testing

Role of Genetic Factors in the Development of Lung Disease

Who this might be right for
Cystic FibrosisPulmonary FibrosisTuberous Sclerosis+2 more
National Heart, Lung, and Blood Institute (NHLBI) 3,500
Not applicableStudy completedNCT03383939
What this trial is testing

Inhaled A1AT in Adult Stable Bronchiectasis

Who this might be right for
Bronchiectasis Adult
Hospital Universitari Vall d'Hebron Research Institute 20
Not applicableLooking for participantsNCT06512454
What this trial is testing

A Study in Adults to Learn About Inherited Alpha-1 Antitrypsin Deficiency (AATD) and AATD Related Liver Problems

Who this might be right for
Alpha1-Antitrypsin Deficiency
Takeda 500
Post-approval studies (Phase 4)Study completedNCT00396006
What this trial is testing

Efficacy and Safety Study of Augmentation Therapy With ARALAST Fraction IV-1 (Human Alpha 1 - Proteinase Inhibitor)

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Baxalta now part of Shire 21
Large-scale testing (Phase 3)Active Not RecruitingNCT05899673
What this trial is testing

An Extension Study to Learn About the Long-Term Safety of Fazirsiran and if Fazirsiran Can Help People With Alpha-1 Antitrypsin Liver Disease

Who this might be right for
Alpha1-Antitrypsin Deficiency
Takeda 31
Large-scale testing (Phase 3)Ended earlyNCT02722304
What this trial is testing

Stage 1 Study of ARALAST NP and GLASSIA in A1PI Deficiency

Who this might be right for
Chronic Obstructive Pulmonary DiseaseAlpha1-antitrypsin Deficiency
Baxalta now part of Shire 7
Early research (Phase 1)Ended earlyNCT04443192
What this trial is testing

A Single Ascending and Repeated Dose Study of Oral ZF874 in Healthy Volunteers and PiXZ Subjects

Who this might be right for
Alpha1 Anti-Trypsin Deficiency
Z Factor Limited 69
Large-scale testing (Phase 3)Looking for participantsNCT06165341
What this trial is testing

Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

Who this might be right for
Alpha1-Antitrypsin Deficiency
Takeda 50
Early research (Phase 1)Ended earlyNCT02503683
What this trial is testing

An Investigational Drug, ALN-AAT, in Healthy Adult Subjects and Patients With ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease

Who this might be right for
Antitrypsin Deficiency Liver Disease
Alnylam Pharmaceuticals 26
Testing effectiveness (Phase 2)Ended earlyNCT04167345
What this trial is testing

Evaluation of the Efficacy and Safety of VX-814 in Subjects With the PiZZ Genotype

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Vertex Pharmaceuticals Incorporated 48
Testing effectiveness (Phase 2)Study completedNCT03008915
What this trial is testing

Targeting Pulmonary Perfusion in Alpha-1 Antitrypsin Deficiency

Who this might be right for
Alpha-1 Antitrypsin DeficiencyEmphysemaChronic Obstructive Pulmonary Disease
Columbia University 15
Testing effectiveness (Phase 2)Ended earlyNCT02093221
What this trial is testing

Study of Human Plasma-Derived Alpha1-Proteinase Inhibitor in Subjects With New-Onset Type 1 Diabetes Mellitus

Who this might be right for
Type 1 Diabetes Mellitus
Grifols Therapeutics LLC 76
Early research (Phase 1)Study completedNCT05579431
What this trial is testing

A Phase 1, First-in-human Study of VX-634

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Vertex Pharmaceuticals Incorporated 127
Large-scale testing (Phase 3)Study completedNCT00295061
What this trial is testing

Comparison of Pharmacokinetic, Safety, Tolerability of Alpha-1 MP and Prolastin In Alpha1-antitrypsin Deficient Adults

Who this might be right for
Alpha 1-Antitrypsin Deficiency
Grifols Therapeutics LLC 24
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