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Results for “RAS-mutant Colorectal Cancer”

46 trials

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Showing 20 of 46 results

Early research (Phase 1)Ended earlyNCT06194877
What this trial is testing

Investigate BGB-3245 (Brimarafenib) With Panitumumab in Participants With Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers

Who this might be right for
Colorectal CancerPancreatic Ductal CancerAdvanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers
MapKure, LLC 13
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06835179
What this trial is testing

SBRT Combined With CAPEOX, Bevacizumab, and PD-1 Inhibitor for the Treatment of RAS-Mutant, MSS-Type, Unresectable Metastatic Colorectal Cancer.

Who this might be right for
Unresectable Metastatic Colorectal CancerMicrosatellite Stable (MSS) Colorectal Cancer (CRC)RAS-mutant Colorectal Cancer
The First Affiliated Hospital with Nanjing Medical University 28
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07198321
What this trial is testing

A Single-Arm, Open-Label, Multicenter Phase I/II Clinical Study of GFH276 in Patients With RAS-Mutant Advanced Solid Tumors

Who this might be right for
CancerPDACCRC (Colorectal Cancer)+1 more
Genfleet Therapeutics (Shanghai) Inc. 450
Testing effectiveness (Phase 2)UnknownNCT04653480
What this trial is testing

Surufatinib, Toripalimab and Chemotherapy in Second-line MT and MSS CRC

Who this might be right for
Colorectal Cancer
Zhejiang University 61
Testing effectiveness (Phase 2)UnknownNCT05842525
What this trial is testing

Fruquintinib Plus FOLFIRI in RAS-mutated Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Hunan Cancer Hospital 42
Testing effectiveness (Phase 2)UnknownNCT05634590
What this trial is testing

The Efficacy and Safety of Fruquintinib Plus FOLFIRI/FOLFOX as Second-line Treatment in Patients With RAS-mutant Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Fudan University 68
Testing effectiveness (Phase 2)Ended earlyNCT01322815
What this trial is testing

A Pilot Trial of GI-4000 Plus Bevacizumab and Either FOLFOX or FOLFIRI

Who this might be right for
Colon Cancer
Georgetown University 11
Testing effectiveness (Phase 2)Study completedNCT01394939
What this trial is testing

Recombinant Vaccinia Virus Administered Intravenously in Patients With Metastatic, Refractory Colorectal Carcinoma

Who this might be right for
Colorectal CarcinomaCRC
Jennerex Biotherapeutics 52
Testing effectiveness (Phase 2)Ended earlyNCT01032291
What this trial is testing

Assess the Efficacy and Safety of Lenalidomide in Combination With Cetuximab in Pre-treated Patients With KRAS Mutant Colorectal Cancer

Who this might be right for
Colorectal Cancer
Celgene Corporation 51
Early research (Phase 1)UnknownNCT04303403
What this trial is testing

Study of Trametinib and Ruxolitinib in Colorectal Cancer and Pancreatic Adenocarcinoma

Who this might be right for
Colorectal CancerPancreatic Adenocarcinoma
National Cancer Centre, Singapore 48
Early research (Phase 1)Study completedNCT03714958
What this trial is testing

Trametinib + HDM201 in CRC Patients With RAS/RAF Mutant and TP53 Wild-type Advanced/Metastatic Colorectal Cancer Mutant and TP53 Wild-type

Who this might be right for
Colorectal CancerAdvanced CancerMetastatic Cancer
Centre Leon Berard 12
Testing effectiveness (Phase 2)UnknownNCT05522738
What this trial is testing

Safety and Efficacy of Fruquintinib+FOLFIRI in RAS-mutated Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Chinese PLA General Hospital 46
Not applicableStudy completedNCT01822444
What this trial is testing

ANGIOPREDICT. ICORG 12-16, V3

Who this might be right for
Advanced Colorectal Cancer
Cancer Trials Ireland 76
Early research (Phase 1)Active Not RecruitingNCT05462717
What this trial is testing

Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors

Who this might be right for
Non-Small Cell Lung Cancer (NSCLC)Colorectal Cancer (CRC)Pancreatic Ductal Adenocarcinoma+1 more
Revolution Medicines, Inc. 222
Large-scale testing (Phase 3)UnknownNCT04781270
What this trial is testing

MFOLFOXIRI+Bev vs. mFOLFOX6+Bev for RAS Mutant Unresectable Colorectal Liver-limited Metastases

Who this might be right for
Colorectal CarcinomaLiver Metastases
Fudan University 308
Testing effectiveness (Phase 2)UnknownNCT01190462
What this trial is testing

Cetuximab and Simvastatin in Treating Patients With Advanced or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Leiden University Medical Center 51
Testing effectiveness (Phase 2)Study completedNCT01927341
What this trial is testing

Phase Ib/II Study of Efficacy and Safety of MEK162 and Panitumumab, in Adult mCRC Patients With Mutant or Wild-type RAS Tumors

Who this might be right for
Metastatic Colorectal Cancer
Pfizer 53
Early research (Phase 1)Study completedNCT02510001
What this trial is testing

MEK and MET Inhibition in Colorectal Cancer

Who this might be right for
Solid TumorColorectal Cancer
University of Oxford 82
Testing effectiveness (Phase 2)UnknownNCT05111860
What this trial is testing

Neoadjuvant Bevacizumab + Chemotherapy Combined With Short-course Radiotherapy

Who this might be right for
Neoadjuvant TreatmentRectal CancerBevacizumab+1 more
Shanghai Minimally Invasive Surgery Center 20
Large-scale testing (Phase 3)WithdrawnNCT01646554
What this trial is testing

Efficacy of FOLFOX Versus FOLFOX Plus Aflibercept in K-ras Mutant Patients With Resectable Liver Metastases

Who this might be right for
Colorectal Cancer MetastaticLiver MetastasesKRAS Mutated Colorectal Cancer
European Organisation for Research and Treatment of Cancer - EORTC
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