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Results for “RAS-mutant Colorectal Cancer”

45 trials

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Showing 20 of 45 results

Testing effectiveness (Phase 2)UnknownNCT01110785
What this trial is testing

Simvastatin and Panitumumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Leiden University Medical Center 46
Not applicableStudy completedNCT01822444
What this trial is testing

ANGIOPREDICT. ICORG 12-16, V3

Who this might be right for
Advanced Colorectal Cancer
Cancer Trials Ireland 76
Testing effectiveness (Phase 2)Looking for participantsNCT06206096
What this trial is testing

PD-1 Antibody Plus Bevacizumab and CAPOX as First-line Treatment for RAS-mut MSS mCRC

Who this might be right for
Colorectal CancerRAS MutationColorectal Neoplasms+1 more
Chinese PLA General Hospital 40
Testing effectiveness (Phase 2)Study completedNCT01927341
What this trial is testing

Phase Ib/II Study of Efficacy and Safety of MEK162 and Panitumumab, in Adult mCRC Patients With Mutant or Wild-type RAS Tumors

Who this might be right for
Metastatic Colorectal Cancer
Pfizer 53
Testing effectiveness (Phase 2)Looking for participantsNCT06128551
What this trial is testing

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

Who this might be right for
Non-Small Cell Lung Cancer (NSCLC)Colorectal CancerPancreatic Ductal Adenocarcinoma
Revolution Medicines, Inc. 534
Testing effectiveness (Phase 2)Study completedNCT03271047
What this trial is testing

Study of Binimetinib + Nivolumab Plus or Minus Ipilimumab in Patients With Previously Treated Microsatellite-stable (MSS) Metastatic Colorectal Cancer With RAS Mutation

Who this might be right for
MSSRAS-mutant Colorectal Cancer
Pfizer 75
Early research (Phase 1)Study completedNCT03597581
What this trial is testing

RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal Cancer

Who this might be right for
Gastrointestinal CancerGastrointestinal NeoplasmsColorectal Cancer+7 more
Inspirna, Inc. 89
Testing effectiveness (Phase 2)UnknownNCT02619435
What this trial is testing

Regorafenib Monotherapy as Second-line Treatment of Patients With RAS-mutant Advanced Colorectal Cancer

Who this might be right for
Advanced Colorectal Cancer
National Cancer Institute, Naples 46
Not applicableUnknownNCT04852250
What this trial is testing

Centralized Tumour Board and Secondary Intervention Rate in mCRC

Who this might be right for
Metastatic Colorectal CancerRAS MutationMultidisciplinary Communication+1 more
Ludwig-Maximilians - University of Munich 130
Testing effectiveness (Phase 2)UnknownNCT01190462
What this trial is testing

Cetuximab and Simvastatin in Treating Patients With Advanced or Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Leiden University Medical Center 51
Large-scale testing (Phase 3)Looking for participantsNCT05171660
What this trial is testing

Combination With Sintilimab and XELOX+Bevacizumab as 1st Line Therapy in RAS-mutant Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer Stage IV
Second Affiliated Hospital, School of Medicine, Zhejiang University 446
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06835179
What this trial is testing

SBRT Combined With CAPEOX, Bevacizumab, and PD-1 Inhibitor for the Treatment of RAS-Mutant, MSS-Type, Unresectable Metastatic Colorectal Cancer.

Who this might be right for
Unresectable Metastatic Colorectal CancerMicrosatellite Stable (MSS) Colorectal Cancer (CRC)RAS-mutant Colorectal Cancer
The First Affiliated Hospital with Nanjing Medical University 28
Testing effectiveness (Phase 2)Ended earlyNCT04853043
What this trial is testing

Cetuximab in Third Line for Mutant APC, TP53 and RAS Patients With Refractory Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
University of Utah 7
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07198321
What this trial is testing

A Single-Arm, Open-Label, Multicenter Phase I/II Clinical Study of GFH276 in Patients With RAS-Mutant Advanced Solid Tumors

Who this might be right for
CancerPDACCRC (Colorectal Cancer)+1 more
Genfleet Therapeutics (Shanghai) Inc. 450
Early research (Phase 1)Study completedNCT02510001
What this trial is testing

MEK and MET Inhibition in Colorectal Cancer

Who this might be right for
Solid TumorColorectal Cancer
University of Oxford 82
Large-scale testing (Phase 3)Looking for participantsNCT04781270
What this trial is testing

MFOLFOXIRI+Bev vs. mFOLFOX6+Bev for RAS Mutant Unresectable Colorectal Liver-limited Metastases

Who this might be right for
Colorectal CarcinomaLiver Metastases
Fudan University 308
Testing effectiveness (Phase 2)Ended earlyNCT01032291
What this trial is testing

Assess the Efficacy and Safety of Lenalidomide in Combination With Cetuximab in Pre-treated Patients With KRAS Mutant Colorectal Cancer

Who this might be right for
Colorectal Cancer
Celgene Corporation 51
Testing effectiveness (Phase 2)Looking for participantsNCT05111860
What this trial is testing

Neoadjuvant Bevacizumab + Chemotherapy Combined With Short-course Radiotherapy

Who this might be right for
Neoadjuvant TreatmentRectal CancerBevacizumab+1 more
Shanghai Minimally Invasive Surgery Center 20
Post-approval studies (Phase 4)Study completedNCT01972490
What this trial is testing

Avastin in Combination With Chemotherapy for RAS Mutant Unresectable Colorectal Liver-limited Metastases

Who this might be right for
Colorectal Neoplasms
Xu jianmin 241
Early research (Phase 1)UnknownNCT04303403
What this trial is testing

Study of Trametinib and Ruxolitinib in Colorectal Cancer and Pancreatic Adenocarcinoma

Who this might be right for
Colorectal CancerPancreatic Adenocarcinoma
National Cancer Centre, Singapore 48
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