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Results for “Ras-mutated Metastatic Colorectal Cancer”

60 trials

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Showing 20 of 60 results

Not applicableLooking for participantsNCT06449989
What this trial is testing

Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Colorectal Cancer

Who this might be right for
Colorectal Cancer MetastaticBrain Metastases, AdultRas (KRAS or NRAS) Gene Mutation+3 more
Blokhin's Russian Cancer Research Center 30
Testing effectiveness (Phase 2)Study completedNCT02414009
What this trial is testing

Study to Compare CAPTEM vs FOLFIRI as Second Line Treatment in Advanced, Colorectal Cancer Patients

Who this might be right for
Metastatic Colorectal Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 82
Testing effectiveness (Phase 2)UnknownNCT05842525
What this trial is testing

Fruquintinib Plus FOLFIRI in RAS-mutated Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
Hunan Cancer Hospital 42
Testing effectiveness (Phase 2)UnknownNCT05634590
What this trial is testing

The Efficacy and Safety of Fruquintinib Plus FOLFIRI/FOLFOX as Second-line Treatment in Patients With RAS-mutant Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Fudan University 68
Large-scale testing (Phase 3)Active Not RecruitingNCT04793958
What this trial is testing

Phase 3 Study of MRTX849 With Cetuximab vs Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation (KRYSTAL-10)

Who this might be right for
Advanced Colorectal CancerMetastatic Colorectal Cancer
Mirati Therapeutics Inc. 461
Testing effectiveness (Phase 2)Looking for participantsNCT06949982
What this trial is testing

Efficacy And Safety Of Hydroxychloroquine Combined With Methotrexate, Capecitabine And Bevacizumab Vs. Regorafenib In Participants With Refractory Metastatic Colorectal Cancer With Mutations In RAS Genes

Who this might be right for
Metastatic Colorectal Cancer (mCRC)Colorectal Neoplasms
Sergey Orlov, MD 60
Not applicableUnknownNCT04397601
What this trial is testing

Aflibercept or Bevacizumab as Second-line Treatment of RAS Mutated Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
National Cancer Institute, Naples 220
Testing effectiveness (Phase 2)UnknownNCT05970302
What this trial is testing

XELOX +Bev +Tislelizumab for First-line Treatment of MSS/pMMR RAS-mutated mCRC

Who this might be right for
TislelizumabBevacizumabOxaliplatin+5 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 52
Early research (Phase 1)Ended earlyNCT05831995
What this trial is testing

Safety and Effectiveness of ABM-168 in Adults with Advanced Solid Tumors.

Who this might be right for
Advanced Solid TumorRAS MutationRAF Mutation+1 more
ABM Therapeutics Corporation 12
Early research (Phase 1)Study completedNCT02906059
What this trial is testing

Study of Irinotecan and AZD1775, a Selective Wee 1 Inhibitor, in RAS or BRAF Mutated, Second-line Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
NYU Langone Health 7
Large-scale testing (Phase 3)Looking for participantsNCT06566755
What this trial is testing

Cadonilimab (AK104) Combined With Chemotherapy and Bevacizumab as First-line Treatment for RAS Mutated or Right Sided-metastatic MSS Colorectal Cancer

Who this might be right for
Colorectal Cancer
Caigang Liu 30
Early research (Phase 1)Ended earlyNCT02313012
What this trial is testing

Safety and PK Study of CC-90003 in Relapsed/Refractory Solid Tumors

Who this might be right for
Neoplasm Metastasis
Celgene 19
Testing effectiveness (Phase 2)UnknownNCT05522738
What this trial is testing

Safety and Efficacy of Fruquintinib+FOLFIRI in RAS-mutated Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Chinese PLA General Hospital 46
Early research (Phase 1)Active Not RecruitingNCT05907304
What this trial is testing

Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With RAS Q61X Mutations

Who this might be right for
Advanced or Metastatic Solid Tumors
Erasca, Inc. 86
Testing effectiveness (Phase 2)Study completedNCT05593328
What this trial is testing

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab Versus FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer in Participants With a Kirsten Rat Sarcoma Virus Gene (KRAS) or Neuroblastoma-RAS (NRAS) Mutation

Who this might be right for
Colorectal CancerMetastatic Colorectal Cancer
Cardiff Oncology 23
Testing effectiveness (Phase 2)Looking for participantsNCT06321081
What this trial is testing

ICE Study: Combination of Irinotecan Plus Cetuximab and Envafolimab as a Rechallenge Regimen in mCRC

Who this might be right for
RAS MutationMetastatic Colorectal CancerMSS
Beijing Hospital 60
Not applicableLooking for participantsNCT04678583
What this trial is testing

Anatomical Resection of Liver MetAstases iN patIents With RAS-mutated Colorectal Cancer

Who this might be right for
Colorectal Liver Metastasis
Technische Universität Dresden 240
Early research (Phase 1)Active Not RecruitingNCT05462717
What this trial is testing

Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors

Who this might be right for
Non-Small Cell Lung Cancer (NSCLC)Colorectal Cancer (CRC)Pancreatic Ductal Adenocarcinoma+1 more
Revolution Medicines, Inc. 222
Early research (Phase 1)Study completedNCT03317119
What this trial is testing

Trametinib and Trifluridine and Tipiracil Hydrochloride in Treating Patients With Colon or Rectal Cancer That is Advanced, Metastatic, or Cannot Be Removed by Surgery

Who this might be right for
Metastatic Colon CarcinomaMetastatic Colorectal CarcinomaMetastatic Rectal Carcinoma+22 more
City of Hope Medical Center 26
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06936527
What this trial is testing

XS-03 in Combination With FOLFOX or FOLFIRI and Bevacizumab for Treatment of Metastatic Colorectal Cancer Patients With RAS Mutation

Who this might be right for
Colorectal CancerMetastatic Colorectal Cancer With RAS Mutation
NovaOnco Therapeutics Co., Ltd. 102
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