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Results for “Refractory”

13,152 trials

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Showing 20 of 13,152 results

Testing effectiveness (Phase 2)Study completedNCT03625323
What this trial is testing

Combination Study With Soluble LAG-3 Fusion Protein Eftilagimod Alpha (IMP321) and Pembrolizumab in Patients With Previously Untreated Unresectable or Metastatic NSCLC, or Recurrent PD-X Refractory NSCLC or With Recurrent or Metastatic HNSCC

Who this might be right for
NSCLCHNSCC
Immutep S.A.S. 187
Testing effectiveness (Phase 2)WithdrawnNCT05279859
What this trial is testing

Anti-Cancer Therapies Targeting the MAPK Pathway in Patients With Hematologic Malignancies

Who this might be right for
Acute Myeloid Leukemia
Erasca, Inc.
Testing effectiveness (Phase 2)Study completedNCT00070694
What this trial is testing

An Investigation of the Antidepressant Efficacy of the 5-HT2A Antagonist, M100907, in Combination With Citalopram in Treatment Resistant Depression

Who this might be right for
Depressive Disorder
National Institute of Mental Health (NIMH) 96
Not applicableUnknownNCT04808856
What this trial is testing

Treatment of Refractory Gout With ACTH or Methylprednisolone

Who this might be right for
Gout
Shanghai 10th People's Hospital 60
Testing effectiveness (Phase 2)Looking for participantsNCT07570862
What this trial is testing

A Phase 2, Open-Label, Single-Arm Trial of FT819 in Participants With Lupus Nephritis

Who this might be right for
Lupus NephritisSystemic Lupus ErythematosusSLE - Systemic Lupus Erythematosus+2 more
Fate Therapeutics 53
Not applicableWithdrawnNCT06508346
What this trial is testing

Study of Therapeutic Efficacy of Anti-CD19 CAR-T Cells in Children With Refractory Refractory AAV

Who this might be right for
ANCA Associated VasculitisCAR-T Cell Therapy
The Children's Hospital of Zhejiang University School of Medicine
Not applicableStudy completedNCT00020527
What this trial is testing

Caspofungin Acetate in Treating Children With Fever and Neutropenia

Who this might be right for
Fever, Sweats, and Hot FlashesInfectionKidney Cancer+5 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Study completedNCT00040586
What this trial is testing

Phase II Trial of Monoclonal Antibody (J591) in Combination With Low-Dose Subcutaneous Interleukin-2

Who this might be right for
Prostatic Neoplasms
BZL Biologics
Testing effectiveness (Phase 2)Ended earlyNCT01093183
What this trial is testing

Lenalidomide and Cyclophosphamide in Treating Patients With Previously Treated Hormone-Refractory Prostate Cancer

Who this might be right for
Adenocarcinoma of the ProstateHormone-resistant Prostate CancerRecurrent Prostate Cancer
University of Nebraska 25
Testing effectiveness (Phase 2)UnknownNCT03245905
What this trial is testing

Study of Chidamide as a Single-agent Treatment for Patients With Relapse or Refractory B-NHL

Who this might be right for
Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma (NHL)
Sun Yat-sen University 100
Not applicableStudy completedNCT01844622
What this trial is testing

Clinical Applications of Domperidone in Patients With Delayed Gastric Emptying

Who this might be right for
Digestive System Disease
Mt. Sinai Medical Center, Miami 37
Testing effectiveness (Phase 2)Study completedNCT02312622
What this trial is testing

Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast Cancer

Who this might be right for
Stage IV Non-small Cell Lung Cancer (NSCLC)Recurrent Non-small Cell Lung Cancer (NSCLC)Extensive-stage Small Cell Lung Cancer (SCLC)+3 more
Joel Neal 27
Large-scale testing (Phase 3)Study completedNCT00240045
What this trial is testing

The Use of Drugs to Improve Kidney Function in Patients With Liver and Kidney Dysfunction

Who this might be right for
Type 2 Hepatorenal SyndromeRefractory Ascites
University of Alberta 9
Testing effectiveness (Phase 2)Study completedNCT00576979
What this trial is testing

Intensity-Modulated Radiation Therapy, Etoposide, and Cyclophosphamide Followed By Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia

Who this might be right for
Leukemia
City of Hope Medical Center 51
Testing effectiveness (Phase 2)Study completedNCT00042003
What this trial is testing

Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Blast Phase Who Are Refractory to Imatinib Mesylate (Gleevec)

Who this might be right for
Chronic Myelogenous Leukemia
Astex Pharmaceuticals, Inc. 40
Testing effectiveness (Phase 2)Looking for participantsNCT03266627
What this trial is testing

Adenovirus-specific Cytotoxic T-lymphocytes for Refractory Adenovirus Infection

Who this might be right for
AdenovirusPrimary Immune Deficiency Disorder
New York Medical College 20
Testing effectiveness (Phase 2)Study completedNCT00003670
What this trial is testing

Hormone Therapy With Arzoxifene Hydrochloride in Treating Women With Metastatic Refractory Ovarian Cancer or Primary Peritoneal Cancer

Who this might be right for
Ovarian CancerPrimary Peritoneal Cavity Cancer
Eli Lilly and Company
Early research (Phase 1)Not Yet RecruitingNCT06712173
What this trial is testing

Linperlisib Combined With EZH2 Inhibitor in Relapsed/Refractory Peripheral T-cell Lymphoma (PTCL)

Who this might be right for
Peripheral T Cell Lymphoma
Institute of Hematology & Blood Diseases Hospital, China 33
Testing effectiveness (Phase 2)UnknownNCT06149169
What this trial is testing

CD19-targeted CAR T Cells for Relapsed and Refractory (R/R) Large B-cell Lymphoma

Who this might be right for
Lymphoma, Non-HodgkinDiffuse Large B Cell Lymphoma
Shanghai Ming Ju Biotechnology Co., Ltd. 10
Testing effectiveness (Phase 2)Study completedNCT00967369
What this trial is testing

Combination Chemotherapy With or Without Bortezomib in Treating Patients With Classical Hodgkin Lymphoma That Has Returned or Does Not Respond to Prior Treatment.

Who this might be right for
Recurrent Classic Hodgkin LymphomaRefractory Classic Hodgkin Lymphoma
M.D. Anderson Cancer Center 20
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