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Results for “Refractory Autoimmune Diseases”

438 trials

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Showing 20 of 438 results

Early research (Phase 1)UnknownNCT05474885
What this trial is testing

BCMA-CD19 cCAR T Cell Treatment of Relapsed/Refractory Systemic Lupus Erythematosus (SLE)

Who this might be right for
Relapsed/Refractory, Systemic Lupus Erythematosus (SLE)
iCell Gene Therapeutics 15
Early research (Phase 1)Looking for participantsNCT07031713
What this trial is testing

Safety, Efficacy and Cellular Metabolic Dynamics of ct1192 in Patients With Moderate to Severe Refractory SLE

Who this might be right for
Systemic Lupus Erythematosus (SLE)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 12
Very early researchLooking for participantsNCT07144462
What this trial is testing

Evaluate the Safety, Tolerability, and Preliminary Efficacy of NEUK203-215 Injection in Adult Chinese Patients With Relapsed/Refractory Autoimmune Diseases

Who this might be right for
Autoimmune
Neukio Biotherapeutics (Shanghai) Co., Ltd. 8
Early research (Phase 1)Not Yet RecruitingNCT07287930
What this trial is testing

YTS109 Cell in Subjects With Relapsed/Refractory Autoimmune Hemolytic Anemia

Who this might be right for
Autoimmune Hemolytic Anemia
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 13
Not applicableLooking for participantsNCT06277427
What this trial is testing

Refractory ANCA Associated Vasculitis and Lupus Nephritis Treated With BCMA-targeting CAR-T Cells

Who this might be right for
Lupus NephritisANCA Associated Vasculitis
Lingli Dong 24
Post-approval studies (Phase 4)Study completedNCT01715831
What this trial is testing

A Long-term Safety Extension Study of Tocilizumab in Brazilian Participants With Rheumatoid Arthritis (RA) Who Completed the Studies ML21530 and MA21488

Who this might be right for
Arthritis, Rheumatoid
Hoffmann-La Roche 26
Early research (Phase 1)Looking for participantsNCT07224373
What this trial is testing

An Open-label Study of AZD0120 in Adults With Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
AstraZeneca 24
Testing effectiveness (Phase 2)Ended earlyNCT00727194
What this trial is testing

Safety and Efficacy Study of Eculizumab in Patients With Refractory Generalized Myasthenia Gravis

Who this might be right for
Myasthenia Gravis
Alexion Pharmaceuticals, Inc. 14
Testing effectiveness (Phase 2)UnknownNCT03633864
What this trial is testing

Fecal Microbiota Transplantation for Refractory IgA Nephropathy

Who this might be right for
IgA Nephropathy
Air Force Military Medical University, China 30
Testing effectiveness (Phase 2)Looking for participantsNCT07053800
What this trial is testing

Obe-cel in Severe, Refractory Systemic Lupus Erythematosus With Active Lupus Nephritis

Who this might be right for
Lupus Nephritis
Autolus Limited 35
Testing effectiveness (Phase 2)Looking for participantsNCT06897930
What this trial is testing

Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

Who this might be right for
Lupus Erythematosus, Systemic
AstraZeneca 150
Large-scale testing (Phase 3)Looking for participantsNCT05531565
What this trial is testing

A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus

Who this might be right for
Subacute Cutaneous Lupus ErythematosusChronic Cutaneous Lupus Erythematosus
Biogen 450
Testing effectiveness (Phase 2)WithdrawnNCT06153095
What this trial is testing

IMPT-514 in Active Refractory Lupus Nephritis (LN) and Systemic Lupus Erythematosus (SLE)

Who this might be right for
Systemic Lupus ErythematosusLupus Nephritis
Lyell Immunopharma, Inc.
Early research (Phase 1)Looking for participantsNCT06925542
What this trial is testing

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

Who this might be right for
SLE (Systemic Lupus)Lupus Erythematosus, SystemicLupus Nephritis+4 more
CRISPR Therapeutics 80
Not applicableStudy completedNCT01672151
What this trial is testing

Efficacy of Rapamycin Therapy With Chronic Immune Thrombocytopenia

Who this might be right for
Immune Thrombocytopenic Purpura
First Affiliated Hospital of Suzhou Medical College 35
Very early researchLooking for participantsNCT07526350
What this trial is testing

MTS109 in Patients With Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusIdiopathic Inflammatory MyopathiesSystemic Sclerosis (SSc)+2 more
Shanghai Changzheng Hospital 15
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07453368
What this trial is testing

Orelabrutinib in the Treatment of Relapsed/Refractory AIHA

Who this might be right for
Autoimmune Hemolytic Anemia (AIHA)
Peking Union Medical College Hospital 50
Early research (Phase 1)Looking for participantsNCT07444307
What this trial is testing

A Clinical Study of Dual-Target, Universal CAR-T Cell Therapy for Refractory Systemic Lupus Erythematosus

Who this might be right for
Systemic Lupus Erythematosus (SLE)
Hangzhou Qihan Biotech Co., Ltd. 18
Testing effectiveness (Phase 2)Study completedNCT02556372
What this trial is testing

Liver Test Study of Using JKB-122 in Autoimmune Hepatitis (AIH) Patients Who Are Refractory or Intolerant to Current Therapies

Who this might be right for
Autoimmune Hepatitis
TaiwanJ Pharmaceuticals Co., Ltd 20
Large-scale testing (Phase 3)UnknownNCT05057481
What this trial is testing

Reappraisal of the Therapies of Refractory Autoimmune Hemolytic Anemia in Systemic Lupus Erythematosus

Who this might be right for
Autoimmune Hemolytic AnemiaSystemic Lupus Erythematosus
Assiut University 30
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