Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Resistant Major Depression”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Not applicableStudy completedNCT07526454
What this trial is testing

Electroconvulsive Therapy Versus Intravenous Ketamine in Treatment-Resistant Major Depressive Disorder

Who this might be right for
Electroconvulsive TherapyIntravenous KetamineTreatment-Resistant+1 more
Tanta University 70
Post-approval studies (Phase 4)Not Yet RecruitingNCT07680140
What this trial is testing

Biomarker-Guided Antidepressant Selection

Who this might be right for
Depression - Major Depressive DisorderTreatment-resistant Depression (TRD)rTMS+2 more
Weill Medical College of Cornell University 27
Post-approval studies (Phase 4)Study completedNCT04957368
What this trial is testing

Sustained Mood Improvement With Laughing Gas Exposure: A Randomized Controlled Pilot Trial

Who this might be right for
Treatment Resistant DepressionMajor Depressive Disorder
Unity Health Toronto 40
Very early researchStudy completedNCT04977674
What this trial is testing

Glutamate and Opioid Mechanisms of Antidepressant Response to Ketamine

Who this might be right for
Depressive Disorder, Treatment-Resistant
King's College London 27
Testing effectiveness (Phase 2)Study completedNCT04437485
What this trial is testing

EIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk

Who this might be right for
DepressionMajor Depressive DisorderDysthymic Disorder+4 more
Indiana University 46
Large-scale testing (Phase 3)Active Not RecruitingNCT05625555
What this trial is testing

Predictors of Intravenous Ketamine Response in TRD

Who this might be right for
Treatment Resistant DepressionMajor Depressive DisorderBipolar Disorder
Abraham Nunes 40
Not applicableStudy completedNCT02376491
What this trial is testing

Efficacy of Intermittent ThetaBurst Stimulation Compared to 10 Hz Stimulation on Dorsolateral Prefrontal Cortex in Treatment Resistant Major Depressive Disorder: a Double-blind Randomized Study

Who this might be right for
DEPRESSION
Nantes University Hospital 60
Not applicableUnknownNCT03257397
What this trial is testing

TBS in Major Depression

Who this might be right for
Treatment Resistant Depression
Rupert Lanzenberger 80
Testing effectiveness (Phase 2)Ended earlyNCT04821271
What this trial is testing

Antidepressant Effects of TS-161 in Treatment-Resistant Depression

Who this might be right for
Major Depressive DisorderTreatment-Resistant DepressionDepression
National Institute of Mental Health (NIMH) 11
Testing effectiveness (Phase 2)Study completedNCT00633399
What this trial is testing

Ziprasidone Augmentation of SSRIs for Patients With Major Depressive Disorder (MDD) That do Not Sufficiently Respond to Treatment With SSRIs

Who this might be right for
Major Depressive Disorder
Massachusetts General Hospital 458
Testing effectiveness (Phase 2)Looking for participantsNCT07512284
What this trial is testing

Mindfulness Engaged Neurostimulation for Depression (MEND II)

Who this might be right for
DepressionTreatment Resistant DepressionMajor Depressive Disorder+2 more
University of California, San Diego 120
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07810738
What this trial is testing

The BAARD Study : Evaluating a Computerized Approach to Treatment Selection in Older Adults With Treatment Resistant Depression.

Who this might be right for
Late Life Treatment Resistant DepressionDepression - Major Depressive DisorderTreatment Resistant Depression
Washington University School of Medicine 300
Not applicableStudy completedNCT03191058
What this trial is testing

Confirmatory Efficacy and Safety Trial of Magnetic Seizure Therapy for Depression

Who this might be right for
DepressionUnipolar DepressionTreatment Resistant Depression
University of Texas Southwestern Medical Center 239
Large-scale testing (Phase 3)Study completedNCT04338321
What this trial is testing

A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder

Who this might be right for
Depressive Disorder, Major
Janssen-Cilag International NV 676
Post-approval studies (Phase 4)WithdrawnNCT01175616
What this trial is testing

Creatine Augmentation in Veterans With SSRI-Resistant Major Depression

Who this might be right for
Major Depressive Disorder
University of Utah
Post-approval studies (Phase 4)Study completedNCT00463580
What this trial is testing

Infliximab for Treatment Resistant Major Depression

Who this might be right for
Depression
Emory University 60
Testing effectiveness (Phase 2)Study completedNCT02484456
What this trial is testing

Antidepressant Effects of the Glycine Receptor Antagonist AV-101 (4-chlorokynurenine) in Major Depressive Disorder

Who this might be right for
Major Depression
National Institute of Mental Health (NIMH) 22
Not applicableUnknownNCT04000022
What this trial is testing

Repetitive Transcranial Magnetic Stimulation in Pharmaco-naïve Patients With Major Depression

Who this might be right for
Major Depressive Disorder
University Hospital, Bonn 20
Not applicableLooking for participantsNCT07127913
What this trial is testing

Closed-Loop Deep Brain Stimulation for Treatment-Resistant Bipolar Depression

Who this might be right for
Bipolar II DisorderBipolar II Disorder, Most Recent Episode Major Depressive
Andrew Krystal 10
Not applicableStudy completedNCT05870501
What this trial is testing

Synaptic Imaging and Network Activity in Treatment Resistant Depression

Who this might be right for
Depressive DisorderDepressive Disorder, MajorDepressive Disorder, Treatment-Resistant+5 more
King's College London 56
Next Page