Not applicableStudy completedNCT07527767What this trial is testingSecondary Use of PARALLEL-HF DataWho this might be right forChronic Heart Failure and Reduced Ejection Fraction (HFrEF) Novartis Pharmaceuticals 236
Not applicableLooking for participantsNCT05498675What this trial is testingEffect of Sacubitril/Valsartan on Cardiac Function in Hypertensive Patients Stratified by BMI: A Real World StudyWho this might be right forSacubitril/ValsartanHypertensionObesity Beijing Friendship Hospital 180
Not applicableUnknownNCT04092309What this trial is testingEffect of Angiotensin Converting Enzyme and Sacubitril Valsartan in Patients After Bone Marrow TransplantationWho this might be right forHematopoietic Stem Cell TransplantationCardiotoxicity University of Athens 90
Testing effectiveness (Phase 2)UnknownNCT05212597What this trial is testingOpen Label RCT for Chronic Severe AR : Entresto vs. CCB/ARBWho this might be right forAortic Valve Insufficiency Samsung Medical Center 100
Large-scale testing (Phase 3)Study completedNCT06149104What this trial is testingA Safety Study of Sacubitril/Valsartan in Japanese Pediatric Patients With Heart Failure Due to Systemic Left Ventricle Systolic Dysfunction Who Have Completed CLCZ696B2319E1 StudyWho this might be right forHeart Failure Novartis Pharmaceuticals 8
Not applicableStudy completedNCT03387163What this trial is testingPatient Reported Outcomes inVestigation Following Initiation of Drug Therapy With Entresto (Sacubitril/Valsartan) in Heart FailureWho this might be right forHeart Failure, Systolic Novartis Pharmaceuticals 402
Large-scale testing (Phase 3)Study completedNCT07704684What this trial is testingAssess Sacubitril/Allisartan and Amlodipine in Patients With Essential Hypertension Uncontrolled With AmlodipineWho this might be right forEssential Hypertension Shenzhen Salubris Pharmaceuticals Co., Ltd. 376
Not applicableStudy completedNCT07088471What this trial is testingCardiac Left Atrial Evaluation and Response in HFrEF With Sacubitril/ValsartanWho this might be right forHeart Failure and Reduced Ejection Fraction Connolly Hospital Blanchardstown 334
Post-approval studies (Phase 4)Study completedNCT05991284What this trial is testingSacubitril-Valsartan in Heart Failure With Preserved Ejection Fraction and Secondary Mitral Valve RegurgitationWho this might be right forHeart Failure With Preserved Ejection FractionFunctional Mitral Regurgitation Ziekenhuis Oost-Limburg 84
Not applicableStudy completedNCT05963282What this trial is testingComparative Effectiveness of Entresto (Sacubitril/Valsartan) Versus ACEi/ARB in de Novo Heart Failure PatientsWho this might be right forde Novo Heart Failure Novartis Pharmaceuticals 9,870
Not applicableNot Yet RecruitingNCT07465666What this trial is testingA Real-world Study of the Effectiveness of Angiotensin Receptor-Neprilysin Inhibitor Therapy in Hypertensive Patients in the United Arab EmiratesWho this might be right forHypertension Novartis Pharmaceuticals 500
Post-approval studies (Phase 4)WithdrawnNCT03279861What this trial is testingSacubitril-valsartan Versus Usual Anti-hypertensives in LVADWho this might be right forCongestive Heart FailureHypertension University of Maryland, Baltimore
Testing effectiveness (Phase 2)Study completedNCT04883528What this trial is testingProtecting With ARNI Against Cardiac Consequences of Coronavirus Disease 2019Who this might be right forCovid19 Duke University 42
Post-approval studies (Phase 4)Study completedNCT02916160What this trial is testingSacubitril-valsartan and Heart Failure Patients : the ENTRESTO-SAS StudyWho this might be right forChronic Heart FailureSleep Apnea Syndrome University Hospital, Montpellier 124
Post-approval studies (Phase 4)Study completedNCT02554890What this trial is testingComparison of Sacubitril/Valsartan Versus Enalapril on Effect on NT-proBNP in Patients Stabilized From an Acute Heart Failure Episode.Who this might be right forAcute Heart Failure Novartis Pharmaceuticals 887
Not applicableStudy completedNCT06090487What this trial is testingIs Sacubitril-valsartan Superior to Dapagliflozin in Improving Myocardial Function PerformanceWho this might be right forHeart Failure Ain Shams University 30
Large-scale testing (Phase 3)Study completedNCT01920711What this trial is testingEfficacy and Safety of LCZ696 Compared to Valsartan, on Morbidity and Mortality in Heart Failure Patients With Preserved Ejection FractionWho this might be right forHeart Failure With Preserved Ejection Fraction Novartis Pharmaceuticals 4,822
Large-scale testing (Phase 3)Study completedNCT03066804What this trial is testingA Randomized, Double-blind Controlled Study Comparing LCZ696 to Medical Therapy for Comorbidities in HFpEF PatientsWho this might be right forHeart Failure With Preserved Ejection Fraction Novartis Pharmaceuticals 2,572
Not applicableStudy completedNCT04434170What this trial is testingEffects of Sacubitril/Valsartan on Exercise Capacity, Natriuretic Peptides and Ventricular Remodeling in Heart FailureWho this might be right forHeart Failure Centro Cardiologico Monzino 112
Post-approval studies (Phase 4)UnknownNCT04572724What this trial is testingThe Effect of Sacubitril/Valsartan on Cardiovascular Events in Dialysis Patients and Efficacy Prediction of Baseline LVEF ValueWho this might be right forPeritoneal Dialysis ComplicationHemodialysis ComplicationHeart Failure Shenzhen Second People's Hospital 120