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Results for “Secondary-progressive Multiple Sclerosis (SPMS)”

50 trials

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Showing 20 of 50 results

Testing effectiveness (Phase 2)WithdrawnNCT01181089
What this trial is testing

Dose Escalation Study to Evaluate the Penetration and Pharmacodynamic Effects of Baminercept in the Cerebrospinal Fluid (CSF)and Safety in Subjects With Secondary Progressive Multiple Sclerosis (SPMS)

Who this might be right for
Secondary Progressive Multiple Sclerosis
Biogen
Testing effectiveness (Phase 2)WithdrawnNCT03696485
What this trial is testing

Study to Assess the Safety and Efficacy of an IT Administration of SCM-010 in SPMS

Who this might be right for
Secondary Progressive Multiple Sclerosis (SPMS)
Stem Cell Medicine Ltd.
Post-approval studies (Phase 4)Study completedNCT04792567
What this trial is testing

Exploring the Immune Response to SARS-CoV-2 modRNA Vaccines in Patients With Secondary Progressive Multiple Sclerosis (AMA-VACC)

Who this might be right for
Secondary Progressive Multiple Sclerosis
Novartis Pharmaceuticals 41
Not applicableStudy completedNCT04239664
What this trial is testing

Acceptance Based Telephone Support When Transitioning to SPMS

Who this might be right for
Secondary Progressive Multiple Sclerosis
University of Nottingham 14
Large-scale testing (Phase 3)Ended earlyNCT02430532
What this trial is testing

BG00012 and Delay of Disability Progression in Secondary Progressive Multiple Sclerosis

Who this might be right for
Multiple Sclerosis, Secondary Progressive
Biogen 58
Not applicableLooking for participantsNCT05177523
What this trial is testing

Imaging the Interplay Between Axonal Damage and Repair in Multiple Sclerosis

Who this might be right for
Multiple Sclerosis (MS)Relapsing-remitting Multiple Sclerosis (RRMS)Secondary-progressive Multiple Sclerosis (SPMS)+1 more
University Hospital, Basel, Switzerland 300
Not applicableStudy completedNCT01647321
What this trial is testing

Functional Electrical Stimulation for Individuals With Secondary Progressive Multiple Sclerosis

Who this might be right for
Secondary Progressive Multiple Sclerosis
Johns Hopkins University 16
Large-scale testing (Phase 3)Study completedNCT04353492
What this trial is testing

An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod to Ofatumumab

Who this might be right for
Relapsing Multiple Sclerosis
Novartis Pharmaceuticals 562
Testing effectiveness (Phase 2)Looking for participantsNCT07477639
What this trial is testing

Treatment of Participants With Primary or Secondary Progressive Multiple Sclerosis

Who this might be right for
Primary Progressive Multiple SclerosisSecondary Progressive Multiple Sclerosis (SPMS)Multiple Sclerosis+2 more
Tr1X, Inc. 39
Large-scale testing (Phase 3)UnknownNCT02220244
What this trial is testing

Effect of MD1003 in Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
MedDay Pharmaceuticals SA 105
Not applicableStudy completedNCT01080014
What this trial is testing

Correlation Between Multiple Sclerosis Functional Composite (MSFC) and Expanded Disability Status Scale (EDSS) in Patients With Multiple Sclerosis (MS) in Argentina

Who this might be right for
Multiple Sclerosis
Merck KGaA, Darmstadt, Germany 252
Not applicableStudy completedNCT03408093
What this trial is testing

Study of Betaferon Adherence in Patients With Multiple Sclerosis Treated With Interferon Beta-1b

Who this might be right for
Multiple Sclerosis
Bayer 120
Not applicableNo Longer AvailableNCT04540861
What this trial is testing

Managed Access Program (MAP) for Patients Diagnosed With Secondary Progressive Multiple Sclerosis With Active Disease

Who this might be right for
Multiple Sclerosis
Novartis Pharmaceuticals
Large-scale testing (Phase 3)Looking for participantsNCT07225504
What this trial is testing

Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis

Who this might be right for
Secondary Progressive Multiple Sclerosis (SPMS)
Novartis Pharmaceuticals 1,275
Not applicableStudy completedNCT01804647
What this trial is testing

Longitudinal Therapeutically Non-interventional Study of MSRV-Env Burden in Patients With Multiple Sclerosis Disease

Who this might be right for
Multiple Sclerosis (MS)Relapsing-Remitting MSPrimary Progressive MS+2 more
GeNeuro Innovation SAS 58
Not applicableStudy completedNCT02207075
What this trial is testing

Measuring Active Microglia in Progressive Multiple Sclerosis

Who this might be right for
Secondary Progressive Multiple Sclerosis
Weill Medical College of Cornell University 50
Early research (Phase 1)Study completedNCT01381354
What this trial is testing

Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS)

Who this might be right for
Multiple Sclerosis
University of Iowa 38
Large-scale testing (Phase 3)Ended earlyNCT01416181
What this trial is testing

A Clinical Study of the Efficacy of Natalizumab on Reducing Disability Progression in Participants With Secondary Progressive Multiple Sclerosis

Who this might be right for
Secondary Progressive Multiple Sclerosis
Biogen 889
Not applicableNot Yet RecruitingNCT07831928
What this trial is testing

Evaluation of an Online, On Demand Multimodal Wellness Program to Reduce Fatigue and Improve Quality of Life in Progressive Multiple Sclerosis.

Who this might be right for
Primary Progressive Multiple Sclerosis (PPMS)Secondary Progressive Multiple Sclerosis (SPMS)
University of Iowa 118
Large-scale testing (Phase 3)Active Not RecruitingNCT05156281
What this trial is testing

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS) (REMODEL-2)

Who this might be right for
Relapsing Multiple Sclerosis
Novartis Pharmaceuticals 1,007
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