Post-approval studies (Phase 4)Study completedNCT01743742What this trial is testingFirst-day High Dose Vitamin C, E in Severe Birth AsphyxiaWho this might be right forBirth Asphyxia Sir Takhtasinhji General Hospital 95
Early research (Phase 1)WithdrawnNCT01904786What this trial is testingMelatonin Treatment for Newborn Infants With Moderate to Severe Hypoxic Ischemic EncephalopathyWho this might be right forNewborn Hypoxic Ischemic Encephalopathy St. Louis University
Testing effectiveness (Phase 2)Study completedNCT04063215What this trial is testingA Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy for the Treatment of Traumatic Brain Injury and Hypoxic-Ischemic EncephalopathyWho this might be right forTraumatic Brain Injury Hope Biosciences LLC 24
Not applicableStudy completedNCT03129620What this trial is testingPharmacokinetics of Ampicillin in Neonates With Moderate to Severe Hypoxic-Ischemic EncephalopathyWho this might be right forHypothermia Drexel University 14
Large-scale testing (Phase 3)UnknownNCT01646619What this trial is testingEfficacy Study of Hypothermia Plus Magnesium Sulphate(MgSO4) in the Management of Term and Near Term Babies With Hypoxic Ischemic EncephalopathyWho this might be right forSevere Hypoxic Ischemic EncephalopathyModerate Hypoxic Ischemic Encephalopathy Sajjad Rahman 300
Very early researchUnknownNCT00526500What this trial is testingEffect of Passive Gait Training on the Cortical Activity in Patients With Severe Brain Injury.Who this might be right forCraniocerebral TraumaTraumatic Brain InjurySubarachnoid Hemorrhage+1 more University of Aarhus 60
Testing effectiveness (Phase 2)Study completedNCT02612155What this trial is testingA Multi-site Study of Autologous Cord Blood Cells for Hypoxic Ischemic EncephalopathyWho this might be right forModerate or Severe Hypoxic-ischemic Encephalopathy in Newborns Michael Cotten 35
Early research (Phase 1)Active Not RecruitingNCT03814356What this trial is testingStimulant Therapy Targeted to Individualized Connectivity Maps to Promote ReACTivation of ConsciousnessWho this might be right forBrain Injury Traumatic Severe (Diagnosis)ComaConsciousness, Level Altered+1 more Massachusetts General Hospital 10
Not applicableLooking for participantsNCT06322732What this trial is testingOptimization of Routine Obstetric and Neonatal Care in the Management of Severe Perinatal Asphyxia in Term or Near-term Newborns: Analysis of Sub-optimal CareWho this might be right forPerinatal Asphyxia Assistance Publique - Hôpitaux de Paris 336
Testing effectiveness (Phase 2)WithdrawnNCT02434965What this trial is testingAutologous Cord Blood and Human Placental Derived Stem Cells in Neonates With Severe Hypoxic-Ischemic EncephalopathyWho this might be right forSevere Hypoxic-ischemic Encephalopathy New York Medical College
Testing effectiveness (Phase 2)Ended earlyNCT01626924What this trial is testing2-Iminobiotin in Neonates With Perinatal AsphyxiaWho this might be right forPerinatal Asphyxia Neurophyxia B.V. 6
Not applicableStudy completedNCT02147275What this trial is testingMonitoring Hypertensive Patients's Cerebral Oxygen SaturationWho this might be right forSurgical Complications From General AnesthesiaHypertensionCerebral Ischemia+1 more Huazhong University of Science and Technology 41
Early research (Phase 1)Study completedNCT03635450What this trial is testingStudy of hCT-MSC in Newborn Infants With Moderate or Severe HIEWho this might be right forModerate to Severe Hypoxic-ischemic Encephalopathy Joanne Kurtzberg, MD 6
Not applicableNot Yet RecruitingNCT07764315What this trial is testingEEG-Based Decision-Support Algorithm for Hypoxic-Ischemic Encephalopathy in Term NewbornsWho this might be right forHypoxic-Ischemic EncephalopathyPerinatal AsphyxiaNeonatal Brain Injury Assistance Publique - Hôpitaux de Paris 310
Not applicableUnknownNCT00788723What this trial is testingCortical Excitability in Patients With Severe Brain InjuryWho this might be right forSevere Traumatic Brain InjurySubarachnoid HemorrhageAnoxic Brain Injury University of Aarhus 45
Very early researchLooking for participantsNCT06747260What this trial is testingFeasibility and Safety of Intranasally Administered Breast Milk in HIEWho this might be right forHypoxic Ischaemic Encephalopathy (HIE)Hypoxic Ischemic Encephalopathy of NewbornNeonatal Encephalopathy+4 more Semmelweis University 10
Not applicableStudy completedNCT01793129What this trial is testingPreemie Hypothermia for Neonatal EncephalopathyWho this might be right forInfant, NewbornHypoxia, BrainHypoxia-Ischemia, Brain+3 more NICHD Neonatal Research Network 168
Testing effectiveness (Phase 2)Looking for participantsNCT05778188What this trial is testingEvaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic HypothermiaWho this might be right forHypoxic-Ischemic Encephalopathy ReAlta Life Sciences, Inc. 70