Not applicableActive Not RecruitingNCT02337244What this trial is testingZimmer POLAR Persona - TKA (EMEA Study)Who this might be right forSevere Knee PainSevere Knee DisabilityOsteoarthritis+3 more Zimmer, GmbH 777
Testing effectiveness (Phase 2)Ended earlyNCT01094262What this trial is testingA Safety and Tolerability Study of JNJ-42160443 in Patients With Moderate to Severe, Chronic Knee Pain From OsteoarthritisWho this might be right forOsteoarthritisOsteoarthritis, KneePain+2 more Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 196
Not applicableWithdrawnNCT04472091What this trial is testingGenicular Artery Embolization (GAE) for Osteoarthritic Knee PainWho this might be right forKnee OsteoarthritisKnee Pain ChronicKnee Pain Swelling+2 more Andrew Picel
Post-approval studies (Phase 4)Study completedNCT01742897What this trial is testingEfficacy and Safety Study of Transdermal Therapeutic System (TTS) Fentanyl in Participants With Osteoarthritis Knee PainWho this might be right forOsteoarthritis, Knee Janssen-Cilag Ltd.,Thailand 35
Large-scale testing (Phase 3)Study completedNCT00348452What this trial is testingA Study Comparing the Effectiveness and Safety of Extended Release Tramadol HCl at 100 mg, 200 mg and 300 mg Doses to Placebo for the Treatment of Moderate to Severe Pain Due to Osteoarthritis (OA)Who this might be right forChronic Pain Bausch Health Americas, Inc. 1,000
Large-scale testing (Phase 3)Study completedNCT05377489What this trial is testingOpen-label Trial to Check the Safety and Tolerability of RTX-GRT7039 Injections for Pain Associated With Osteoarthritis of the KneeWho this might be right forOsteoarthritis Grünenthal GmbH 714
Not applicableEnded earlyNCT04349956What this trial is testingLong-Term Follow-Up Study of Patients With Osteoarthritis of the Knee Treated With UBX0101 or PlaceboWho this might be right forKnee Osteoarthritis Unity Biotechnology, Inc. 161
Large-scale testing (Phase 3)Ended earlyNCT03349645What this trial is testingOpen Label Extension to Assess the Safety of Long-Term Treatment With Ampion for Severe Osteoarthritis (OA) of the KneeWho this might be right forSevere Osteoarthritis of the Knee Ampio Pharmaceuticals. Inc. 94
Testing effectiveness (Phase 2)Ended earlyNCT00973141What this trial is testingA Dose-ranging Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Osteoarthritis-related PainWho this might be right forOsteoarthritisOsteoarthritis, HipOsteoarthritis, Knee+3 more Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 467
Testing effectiveness (Phase 2)Study completedNCT01688934What this trial is testingAnalgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis (OA) of the KneeWho this might be right forOsteoarthritis, KneePain Purdue Pharma LP 230
Not applicableStudy completedNCT03719417What this trial is testingA Biologic Joint Replacement Strategy for Knee Trauma and Post-Traumatic OsteoarthritisWho this might be right forKnee OsteoarthritisPost-traumatic Osteoarthritis University of Missouri-Columbia 14
Large-scale testing (Phase 3)Study completedNCT03182686What this trial is testingAP-003-C Study to Confirm the Efficacy of Ampion™ in Adults With Pain Due to Severe Osteoarthritis of the KneeWho this might be right forOsteoarthritis, KneeKnee OsteoarthritisKnee Arthritis+1 more Ampio Pharmaceuticals. Inc. 168
Post-approval studies (Phase 4)Study completedNCT00399178What this trial is testingA Randomised Open Controlled Parallel Group Study Comparing Norspan and TramadolWho this might be right forOsteoarthritis Mundipharma AB 160
Large-scale testing (Phase 3)Study completedNCT01887678What this trial is testingStudy of Intra-articular Injections vs Placebo in Patients With Pain From Osteoarthritis of the KneeWho this might be right forOsteoarthritis, Knee Biologische Heilmittel Heel GmbH 287
Large-scale testing (Phase 3)Study completedNCT03660943What this trial is testingA Clinical Study to Test Efficacy and Safety of Repeat Doses of CNTX-4975-05 in Patients With Osteoarthritis Knee PainWho this might be right forOsteoarthritis, Knee Centrexion Therapeutics 332
Early research (Phase 1)Study completedNCT03491904What this trial is testingTo Assess the Patients' Ability to Self-Administer FasinumabWho this might be right forOsteoarthritis, KneeOsteoarthritis, Hip Regeneron Pharmaceuticals 100
Testing effectiveness (Phase 2)Ended earlyNCT05838742What this trial is testingA Dose-Finding Study to Evaluate the Efficacy and Safety of GSK3858279 in Adults With Knee Osteoarthritis (OA) PainWho this might be right forPainOsteoarthritis, Knee GlaxoSmithKline 314
Testing effectiveness (Phase 2)Study completedNCT00745069What this trial is testingEfficacy and Safety of Tapentadol Extended Release Tablets in the Treatment of Moderate to Severe Pain in Subjects With Knee OsteoarthritisWho this might be right forOsteoarthitisChronic PainKnee Pain Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 670
Large-scale testing (Phase 3)Study completedNCT00833911What this trial is testingAn Open-Label Long-term Safety Study of Tramadol HCl OAD (Once A Day) 300 mg in the Treatment of Pain Due to Osteoarthritis of the KneeWho this might be right forOsteoarthritis, Knee Labopharm Inc. 392
Testing effectiveness (Phase 2)Study completedNCT00979953What this trial is testingEfficacy and Safety Study Evaluating ADL5859 and ADL5747 in Participants With Pain Due to Osteoarthritis of the KneeWho this might be right forOsteoarthritis of the Knee Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 408