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Results for “Severe Knee Pain”

93 trials

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Showing 20 of 93 results

Testing effectiveness (Phase 2)Study completedNCT00979953
What this trial is testing

Efficacy and Safety Study Evaluating ADL5859 and ADL5747 in Participants With Pain Due to Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis of the Knee
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 408
Testing effectiveness (Phase 2)Ended earlyNCT05838742
What this trial is testing

A Dose-Finding Study to Evaluate the Efficacy and Safety of GSK3858279 in Adults With Knee Osteoarthritis (OA) Pain

Who this might be right for
PainOsteoarthritis, Knee
GlaxoSmithKline 314
Not applicableStudy completedNCT06664905
What this trial is testing

Resistance Exercise in Severe Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
University of Valencia 28
Early research (Phase 1)Study completedNCT04229225
What this trial is testing

Single and Repeat Dose Administration of UBX0101 in Patients With Osteoarthritis of the Knee

Who this might be right for
Knee Osteoarthritis
Unity Biotechnology, Inc. 35
Not applicableStudy completedNCT02712749
What this trial is testing

Use of Binaural Beat Premedication in Elderly Submitted to Major Orthopedic Surgery

Who this might be right for
AnxietyPostoperative PainMorphine Consumption
Azienda USL Toscana Nord Ovest 40
Large-scale testing (Phase 3)WithdrawnNCT04044742
What this trial is testing

Evaluate the Efficacy and Safety of Resiniferatoxin for Pain Due to Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis, KneeKnee Pain Chronic
Sorrento Therapeutics, Inc.
Testing effectiveness (Phase 2)Ended earlyNCT02847702
What this trial is testing

Evaluate the Analgesic Efficacy and Safety of VM902A in Subjects With Osteoarthritis (OA) of the Knee

Who this might be right for
Osteoarthritis Pain of the Knee
Purdue Pharma LP 75
Large-scale testing (Phase 3)Study completedNCT00980798
What this trial is testing

Placebo-controlled Trial With OROS Hydromorphone Hydrochloride to Treat Patients With Moderate to Severe Pain Induced by Osteoarthritis of the Hip or the Knee

Who this might be right for
PainOsteoarthritis, HipOsteoarthritis, Knee
Janssen-Cilag International NV 288
Testing effectiveness (Phase 2)Study completedNCT01619839
What this trial is testing

Assess The Efficacy, Tolerability, And Safety OF NKTR-181 In Subjects With Chronic OA Knee Pain

Who this might be right for
Osteoarthritis of the Knee
Nektar Therapeutics 296
Large-scale testing (Phase 3)Study completedNCT00420992
What this trial is testing

Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or Knee

Who this might be right for
OsteoarthritisChronic Pain
Pfizer 547
Testing effectiveness (Phase 2)Study completedNCT04129944
What this trial is testing

Assess the Safety and Efficacy of a Single Dose of UBX0101 in Patients With Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis, Knee
Unity Biotechnology, Inc. 183
Not applicableActive Not RecruitingNCT05112926
What this trial is testing

Effectiveness and Safety of Embosphere Microspheres for Embolization of the Geniculate Artery for the Treatment of Pain With Known Moderate to Severe Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
University of Miami 9
Testing effectiveness (Phase 2)Study completedNCT05079035
What this trial is testing

Lyophilized and Micronized Particulate Human Amniotic and Umbilical Cord (TTAX03) for KL Grade 3-4 Knee OA

Who this might be right for
Knee OsteoarthritisKnee Pain ChronicKnee Arthritis
BioTissue Holdings, Inc 90
Not applicableUnknownNCT05684107
What this trial is testing

Sciatic Nerve Block, Adductor Canal Block, or IPACK Block

Who this might be right for
Post Operative Pain
Menoufia University 150
Testing effectiveness (Phase 2)Study completedNCT00669409
What this trial is testing

A Phase 1/2A, Single Dose Study Of PF-04383119 In Japanese Patients With Moderate To Severe Pain From Osteoarthritis Of The Knee

Who this might be right for
Osteoarthritis, Knee
Pfizer 83
Large-scale testing (Phase 3)Study completedNCT00348452
What this trial is testing

A Study Comparing the Effectiveness and Safety of Extended Release Tramadol HCl at 100 mg, 200 mg and 300 mg Doses to Placebo for the Treatment of Moderate to Severe Pain Due to Osteoarthritis (OA)

Who this might be right for
Chronic Pain
Bausch Health Americas, Inc. 1,000
Testing effectiveness (Phase 2)Study completedNCT00667654
What this trial is testing

Safety and Tolerability of 4975 in the Treatment of Moderate to Severe Knee Pain Due to Osteoarthritis (OA)

Who this might be right for
Osteoarthritis of the Knee
Centrexion Therapeutics 54
Large-scale testing (Phase 3)Study completedNCT03661996
What this trial is testing

An Open-label, 8-week Safety, Efficacy, and Assessment of Cooling Methods for Administration of CNTX-4975-05 for Knee OA

Who this might be right for
Knee Osteoarthritis
Centrexion Therapeutics 854
Not applicableStudy completedNCT03719417
What this trial is testing

A Biologic Joint Replacement Strategy for Knee Trauma and Post-Traumatic Osteoarthritis

Who this might be right for
Knee OsteoarthritisPost-traumatic Osteoarthritis
University of Missouri-Columbia 14
Testing effectiveness (Phase 2)Study completedNCT02558439
What this trial is testing

Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Chronic, Moderate to Severe Osteoarthritis Knee Pain

Who this might be right for
Osteoarthritis
Centrexion Therapeutics 175
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