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Results for “Severe Osteoarthritis of the Knee”

128 trials

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Showing 20 of 128 results

Testing effectiveness (Phase 2)Ended earlyNCT01094262
What this trial is testing

A Safety and Tolerability Study of JNJ-42160443 in Patients With Moderate to Severe, Chronic Knee Pain From Osteoarthritis

Who this might be right for
OsteoarthritisOsteoarthritis, KneePain+2 more
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 196
Not applicableStudy completedNCT06134115
What this trial is testing

LIKEST Study: Lipocet® in Adults With Primary Knee Osteoarthritis Grade 3-4

Who this might be right for
Primary Knee Osteoarthritis Grade 3 - 4
Pharmanutra S.p.a. 60
Not applicableWithdrawnNCT04472091
What this trial is testing

Genicular Artery Embolization (GAE) for Osteoarthritic Knee Pain

Who this might be right for
Knee OsteoarthritisKnee Pain ChronicKnee Pain Swelling+2 more
Andrew Picel
Post-approval studies (Phase 4)Study completedNCT01742897
What this trial is testing

Efficacy and Safety Study of Transdermal Therapeutic System (TTS) Fentanyl in Participants With Osteoarthritis Knee Pain

Who this might be right for
Osteoarthritis, Knee
Janssen-Cilag Ltd.,Thailand 35
Large-scale testing (Phase 3)Study completedNCT00348452
What this trial is testing

A Study Comparing the Effectiveness and Safety of Extended Release Tramadol HCl at 100 mg, 200 mg and 300 mg Doses to Placebo for the Treatment of Moderate to Severe Pain Due to Osteoarthritis (OA)

Who this might be right for
Chronic Pain
Bausch Health Americas, Inc. 1,000
Testing effectiveness (Phase 2)Not Yet RecruitingNCT04750252
What this trial is testing

Safety and Tolerability of StroMel™ in Subjects with Moderate to Severe Osteoarthritis of the Knee Joint

Who this might be right for
Osteo Arthritis Knee
Akan Biosciences, LLC 20
Testing effectiveness (Phase 2)Ended earlyNCT03706521
What this trial is testing

MRI Study to Evaluate the Safety and Efficacy of SM04690 for Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
Biosplice Therapeutics, Inc. 13
Testing effectiveness (Phase 2)Study completedNCT05437601
What this trial is testing

Effect of Astaxanthin in Moderate to Severe Knee Osteoarthritis

Who this might be right for
Osteoarthritis, Knee
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 80
Large-scale testing (Phase 3)Study completedNCT05377489
What this trial is testing

Open-label Trial to Check the Safety and Tolerability of RTX-GRT7039 Injections for Pain Associated With Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis
Grünenthal GmbH 714
Not applicableEnded earlyNCT04349956
What this trial is testing

Long-Term Follow-Up Study of Patients With Osteoarthritis of the Knee Treated With UBX0101 or Placebo

Who this might be right for
Knee Osteoarthritis
Unity Biotechnology, Inc. 161
Not applicableActive Not RecruitingNCT05727371
What this trial is testing

Combination of PRP and XLHA Prepared With RegenMatrix Medical Device To Treat Moderate to Severe Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
RegenLab France SAS 280
Large-scale testing (Phase 3)Ended earlyNCT03349645
What this trial is testing

Open Label Extension to Assess the Safety of Long-Term Treatment With Ampion for Severe Osteoarthritis (OA) of the Knee

Who this might be right for
Severe Osteoarthritis of the Knee
Ampio Pharmaceuticals. Inc. 94
Not applicableLooking for participantsNCT05488093
What this trial is testing

Evaluation of Mobility in Subjects With Severe Knee Osteoarthritis Who Are to Undergo Total Knee Replacement

Who this might be right for
Knee Osteoarthritis
University Hospital, Montpellier 20
Testing effectiveness (Phase 2)Ended earlyNCT00973141
What this trial is testing

A Dose-ranging Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Osteoarthritis-related Pain

Who this might be right for
OsteoarthritisOsteoarthritis, HipOsteoarthritis, Knee+3 more
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 467
Not applicableLooking for participantsNCT05936814
What this trial is testing

Adductor Ratio in Severe Varus Gonarthrosis

Who this might be right for
Osteoarthritis, KneeGenu VarumJoint Prosthesis; Complications
Saglik Bilimleri Universitesi 68
Early research (Phase 1)Study completedNCT01585857
What this trial is testing

ADIPOA - Clinical Study

Who this might be right for
Osteoarthritis
University Hospital, Montpellier 18
Testing effectiveness (Phase 2)Active Not RecruitingNCT04875754
What this trial is testing

A Study Evaluating the Safety, Tolerability, and Range of Biologically Active Doses of ICM-203 in Mild to Moderate Knee Osteoarthritis

Who this might be right for
Osteoarthritis, Knee
ICM Biotech Australia Pty Ltd. 16
Testing effectiveness (Phase 2)Study completedNCT01688934
What this trial is testing

Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis (OA) of the Knee

Who this might be right for
Osteoarthritis, KneePain
Purdue Pharma LP 230
Not applicableStudy completedNCT03719417
What this trial is testing

A Biologic Joint Replacement Strategy for Knee Trauma and Post-Traumatic Osteoarthritis

Who this might be right for
Knee OsteoarthritisPost-traumatic Osteoarthritis
University of Missouri-Columbia 14
Not applicableActive Not RecruitingNCT05972525
What this trial is testing

What Matters to Patients With Severe Hip or Knee Osteoarthritis?

Who this might be right for
Hip OsteoarthritisKnee Osteoarthritis
Vejle Hospital 615
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