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Results for “Severe Osteoarthritis of the Knee”

130 trials

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Showing 20 of 130 results

Post-approval studies (Phase 4)Study completedNCT00426647
What this trial is testing

Norspan® Patches Versus Tramadol in Subjects With Chronic, Moderate to Severe Osteoarthritis Pain in the Hip Knee and/or Lumbar Spine

Who this might be right for
OsteoarthritisPain
Norpharma A/S 120
Large-scale testing (Phase 3)Study completedNCT03661996
What this trial is testing

An Open-label, 8-week Safety, Efficacy, and Assessment of Cooling Methods for Administration of CNTX-4975-05 for Knee OA

Who this might be right for
Knee Osteoarthritis
Centrexion Therapeutics 854
Testing effectiveness (Phase 2)UnknownNCT04885972
What this trial is testing

Study to Evaluate Intra-articular Resiniferatoxin to Treat Moderate to Severe Pain From Knee Osteoarthritis

Who this might be right for
Osteoarthritis, KneeKnee OsteoarthritisKnee Pain Chronic
Sorrento Therapeutics, Inc. 124
Testing effectiveness (Phase 2)Not Yet RecruitingNCT04750252
What this trial is testing

Safety and Tolerability of StroMel™ in Subjects with Moderate to Severe Osteoarthritis of the Knee Joint

Who this might be right for
Osteo Arthritis Knee
Akan Biosciences, LLC 20
Large-scale testing (Phase 3)Study completedNCT00531427
What this trial is testing

Buprenorphine Transdermal System (BTDS) in Subjects w/Mod-sev Osteoarthritis (OA) Chronic Pain of Knee

Who this might be right for
Chronic PainOsteoarthritis of the Knee
Purdue Pharma LP 567
Not applicableUnknownNCT04006314
What this trial is testing

Platelet Rich Plasma and Neural Prolotherapy Injections in Treating Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
Chang Gung Memorial Hospital 24
Early research (Phase 1)Study completedNCT01585857
What this trial is testing

ADIPOA - Clinical Study

Who this might be right for
Osteoarthritis
University Hospital, Montpellier 18
Large-scale testing (Phase 3)Study completedNCT00348452
What this trial is testing

A Study Comparing the Effectiveness and Safety of Extended Release Tramadol HCl at 100 mg, 200 mg and 300 mg Doses to Placebo for the Treatment of Moderate to Severe Pain Due to Osteoarthritis (OA)

Who this might be right for
Chronic Pain
Bausch Health Americas, Inc. 1,000
Large-scale testing (Phase 3)Study completedNCT00420992
What this trial is testing

Embeda (Kadian NT, ALO-01) in Subjects With Pain Due to Osteoarthritis of the Hip or Knee

Who this might be right for
OsteoarthritisChronic Pain
Pfizer 547
Large-scale testing (Phase 3)Study completedNCT01559701
What this trial is testing

Long-term Safety of PF-00345439 (Oxycodone)

Who this might be right for
Pain
Pain Therapeutics 823
Not applicableStudy completedNCT06664905
What this trial is testing

Resistance Exercise in Severe Knee Osteoarthritis

Who this might be right for
Knee Osteoarthritis
University of Valencia 28
Testing effectiveness (Phase 2)Study completedNCT05025787
What this trial is testing

Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Knee Osteoarthritis Pain.

Who this might be right for
Knee Osteoarthritis
Maurizio Fava, MD 55
Not applicableUnknownNCT02722772
What this trial is testing

Efficacy of Intra-Articular Injection of Etanercept for Moderate and Severe Knee Osteoarthritis

Who this might be right for
Osteoarthritis of Knee
First Affiliated Hospital of Harbin Medical University 60
Not applicableUnknownNCT03065738
What this trial is testing

Effect of RO On GB During TKR Severe Varus Deformity

Who this might be right for
Genu VarumKnee Osteoarthritis
Assiut University 30
Not applicableStudy completedNCT00790985
What this trial is testing

Efficacy of Flavocoxid 500 mg Compared With Naproxen 500 mg in Subjects With Moderate-severe Osteoarthritis of the Knee

Who this might be right for
Osteoarthritis of Knee
Primus Pharmaceuticals 223
Testing effectiveness (Phase 2)Ended earlyNCT00973141
What this trial is testing

A Dose-ranging Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Osteoarthritis-related Pain

Who this might be right for
OsteoarthritisOsteoarthritis, HipOsteoarthritis, Knee+3 more
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 467
Large-scale testing (Phase 3)Study completedNCT00983073
What this trial is testing

Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Pain Due to Osteoarthritis Taking Either WHO Step I or Step II Analgesics or no Regular Analgesic

Who this might be right for
Chronic PainOsteoarthritis
Grünenthal GmbH 224
Testing effectiveness (Phase 2)Ended earlyNCT01094262
What this trial is testing

A Safety and Tolerability Study of JNJ-42160443 in Patients With Moderate to Severe, Chronic Knee Pain From Osteoarthritis

Who this might be right for
OsteoarthritisOsteoarthritis, KneePain+2 more
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 196
Not applicableLooking for participantsNCT05936814
What this trial is testing

Adductor Ratio in Severe Varus Gonarthrosis

Who this might be right for
Osteoarthritis, KneeGenu VarumJoint Prosthesis; Complications
Saglik Bilimleri Universitesi 68
Large-scale testing (Phase 3)Ended earlyNCT00982280
What this trial is testing

Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Pain Due to Osteoarthritis Taking WHO Step III Analgesics But Showing a Lack of Tolerability.

Who this might be right for
Chronic PainOsteoarthritis
Grünenthal GmbH 82
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