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Results for “Severe Primary Immunodeficiency Disorder”

105 trials

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Showing 20 of 105 results

Testing effectiveness (Phase 2)Looking for participantsNCT03538899
What this trial is testing

Autologous Gene Therapy for Artemis-Deficient SCID

Who this might be right for
Severe Combined Immunodeficiency
University of California, San Francisco 24
Testing effectiveness (Phase 2)WithdrawnNCT04370795
What this trial is testing

Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning With h-ATG, Radiation, and Sirolimus

Who this might be right for
Severe Combined Immune Deficiency (SCID)
National Institute of Allergy and Infectious Diseases (NIAID)
Not applicableEnrolling By InvitationNCT00895271
What this trial is testing

Establishing Fibroblast-Derived Cell Lines From Skin Biopsies of Patients With Immunodeficiency or Immunodysregulation Disorders

Who this might be right for
Primary ImmunodeficiencyDOCK8Virus Susceptibility
National Institute of Allergy and Infectious Diseases (NIAID) 200
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Not applicableActive Not RecruitingNCT05236764
What this trial is testing

Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion

Who this might be right for
Acute Lymphoblastic Leukemia in RemissionAcute Myeloid Leukemia in RemissionMyelodysplastic Syndromes+8 more
Baylor College of Medicine 3
Testing effectiveness (Phase 2)Study completedNCT00794508
What this trial is testing

MND-ADA Transduction of CD34+ Cells From Children With ADA-SCID

Who this might be right for
Severe Combined Immunodeficiency
Donald B. Kohn, M.D. 10
Large-scale testing (Phase 3)Study completedNCT01019876
What this trial is testing

Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases

Who this might be right for
Bone Marrow FailureOsteopetrosisFanconi Anemia+1 more
Columbia University 38
Testing effectiveness (Phase 2)Study completedNCT01129544
What this trial is testing

Gene Transfer for Severe Combined Immunodeficiency, X-linked (SCID-X1) Using a Self-inactivating (SIN) Gammaretroviral Vector

Who this might be right for
Severe Combined Immunodeficiency
David Williams 8
Testing effectiveness (Phase 2)Ended earlyNCT01182675
What this trial is testing

Hematopoietic Stem Cell Transplantation (HSCT) for Children With SCID Utilizing Alemtuzumab, Plerixafor & Filgrastim

Who this might be right for
Severe Combined Immunodeficiency
University of California, San Francisco 7
Not applicableWithdrawnNCT04331483
What this trial is testing

Assess a Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Allografts

Who this might be right for
Haematological MalignancyAcute LeukemiaMyelodysplastic Syndromes+3 more
Centre Leon Berard
Testing effectiveness (Phase 2)Active Not RecruitingNCT01966367
What this trial is testing

CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation

Who this might be right for
Bone Marrow Failure SyndromeSevere Aplastic AnemiaSevere Congenital Neutropenia+13 more
Diane George 37
Not applicableStudy completedNCT00845416
What this trial is testing

Newborn Screening for Severe Combined Immunodeficiency (SCID) in a High-Risk Population

Who this might be right for
Severe Combined ImmunodeficiencyT Cell Lymphocytopenia
University of California, San Francisco 1,800
Testing effectiveness (Phase 2)UnknownNCT03315078
What this trial is testing

Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age With X-Linked Severe Combined Immunodeficiency

Who this might be right for
X-Linked Combined Immunodeficiency Diseases
National Institute of Allergy and Infectious Diseases (NIAID) 13
Early research (Phase 1)Looking for participantsNCT05077527
What this trial is testing

Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

Who this might be right for
AIDS-Related Diffuse Large B-cell LymphomaAIDS-Related Non-Hodgkin LymphomaHIV Infection+12 more
AIDS Malignancy Consortium 20
Early research (Phase 1)Study completedNCT00692926
What this trial is testing

Unrelated Umbilical Cord Blood Transplantation Augmented With ALDHbr Umbilical Cord Blood Cells

Who this might be right for
MDSAnemia, AplasticInborn Errors of Metabolism+2 more
Joanne Kurtzberg, MD 37
Large-scale testing (Phase 3)Study completedNCT01420627
What this trial is testing

EZN-2279 in Patients With ADA-SCID

Who this might be right for
ADA-SCIDAdenosine Deaminase DeficiencySevere Combined Immunodeficiency
Leadiant Biosciences, Inc. 7
Not applicableUnknownNCT02231983
What this trial is testing

Clinical Characteristics and Genetic Profiles of Severe Combined Immunodeficiency in China

Who this might be right for
Severe Combined Immunodeficiency
Shanghai Children's Medical Center 50
Testing effectiveness (Phase 2)Looking for participantsNCT05071222
What this trial is testing

Safety and Efficacy Study of Transplantation of Autologous CD34+ Cells Transduced With the G2ARTE Lentiviral Vector Expressing the DCLRE1C cDNA in Artemis (DCLRE1C) Deficient Severe Combined Immunodeficiency Patients (ARTEGENE)

Who this might be right for
Artemis (DCLRE1C ) Deficient Severe Combined Immunodeficiency
Assistance Publique - Hôpitaux de Paris 7
Testing effectiveness (Phase 2)Study completedNCT00599781
What this trial is testing

Gene Therapy for ADA-SCID

Who this might be right for
Severe Combined Immunodeficiency Syndrome
IRCCS San Raffaele 8
Testing effectiveness (Phase 2)Ended earlyNCT00579137
What this trial is testing

Allogeneic SCT Of Pts With SCID And Other Primary Immunodeficiency Disorders

Who this might be right for
Severe Combined Immunodeficiency DiseaseSevere Primary Immunodeficiency DisorderUndefined T Cell Deficiency Disorder+1 more
Baylor College of Medicine 3
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