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Results for “Severe Renal Impairment”

414 trials

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Showing 20 of 414 results

Not applicableWithdrawnNCT03998917
What this trial is testing

Pathophysiological Characterization of the Neuromuscular Function of a Population With Multiple Comorbidities Suffering From Chronic Renal Failure in Pre-dialysis.

Who this might be right for
Chronic Kidney FailureChronic Kidney Disease stage3Chronic Kidney Disease, Stage 4 (Severe)+2 more
Centre Hospitalier le Mans
Early research (Phase 1)Active Not RecruitingNCT07154901
What this trial is testing

Investigation of the Effects of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of Opemalirsen (AZD2373)

Who this might be right for
Renal Impairment
AstraZeneca 34
Post-approval studies (Phase 4)Looking for participantsNCT06725810
What this trial is testing

Correction of Anemia With Enarodustat in Non-dialysis Dependent Chronic Kidney Disease

Who this might be right for
Chronic Kidney Disease Associated Anemia
Shanghai Zhongshan Hospital 1,670
Post-approval studies (Phase 4)Study completedNCT01043094
What this trial is testing

Safety, Tolerability, and Pharmacokinetic of Single Dose of Pitavastatin 4 mg in Severe Renal Patients Versus Healthy Adult Volunteers

Who this might be right for
Severe Renal Impairment
Kowa Research Institute, Inc. 16
Post-approval studies (Phase 4)UnknownNCT00837057
What this trial is testing

Early Continuous Renal Replacement Therapies (CRRT) in Patients With Severe Sepsis or Septic Shock With Acute Kidney Injury

Who this might be right for
Severe SepsisSeptic ShockAcute Kidney Injury
Asan Medical Center 60
Large-scale testing (Phase 3)Study completedNCT00500682
What this trial is testing

AST-120 for Evaluating Prevention of Progression In Chronic Kidney Disease (EPPIC-1)

Who this might be right for
Chronic Kidney Disease
Tanabe Pharma Corporation 1,020
Large-scale testing (Phase 3)Study completedNCT01377246
What this trial is testing

Somatostatin In Patients With Autosomal Dominant Polycystic Kidney Disease And Moderate To Severe Renal Insufficiency

Who this might be right for
Autosomal Dominant Polycystic Kidney Disease
Mario Negri Institute for Pharmacological Research 100
Early research (Phase 1)Study completedNCT00731523
What this trial is testing

Pharmacokinetics (PK) and Metabolism of FTY720 in Patients With Severe Renal Impairment and Healthy Matched Subjects.

Who this might be right for
Renal Insufficiency
Novartis 18
Not applicableActive Not RecruitingNCT06819345
What this trial is testing

Impact of PREMs in the Shared Decision Process for Renal Replacement Treatment Methods.

Who this might be right for
Chronic Kidney Disease, Stage 4 (Severe)Chronic Kidney Disease, Stage 5
Hospices Civils de Lyon 70
Not applicableUnknownNCT03046914
What this trial is testing

HLA-B*5801 Screening to Prevent Allopurinol-induced Severe Cutaneous Adverse Reaction

Who this might be right for
Stevens-Johnson SyndromeKidney Failure, Chronic
Seoul National University Hospital 600
Testing effectiveness (Phase 2)Ended earlyNCT01897519
What this trial is testing

A Safety and Efficacy Trial of Multiple Dosing Regimens of ABT-719 for the Prevention of Acute Kidney Injury in Subjects Undergoing High Risk Surgery

Who this might be right for
Cardiothoracic SurgeryVascular Surgery
AbbVie 56
Large-scale testing (Phase 3)Study completedNCT01087502
What this trial is testing

Safety and Efficacy of Linagliptin in Type-2-diabetes Mellitus Patients With Moderate to Severe Renal Impairment

Who this might be right for
Diabetes Mellitus, Type 2
Boehringer Ingelheim 241
Not applicableWithdrawnNCT02599844
What this trial is testing

Impact of Pediatric Acute Renal Injury in Severe Sepsis in Young Adults

Who this might be right for
Acute Kidney InjuryChronic Kidney DiseaseHypertension
University of Florida
Large-scale testing (Phase 3)Enrolling By InvitationNCT05374291
What this trial is testing

The RENAL LIFECYCLE Trial: A RCT to Assess the Effect of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Severe CKD

Who this might be right for
Kidney Disease, ChronicRenal Transplant FailureHeart Failure+2 more
University Medical Center Groningen 1,750
Early research (Phase 1)Study completedNCT01853046
What this trial is testing

Pharmacokinetics and Safety of Regorafenib (BAY73-4506) in Cancer Subjects With Severe Renal Impairment

Who this might be right for
Neoplasms
Bayer 24
Not applicableStudy completedNCT04979754
What this trial is testing

REnal TRansplant Outcomes After CARdiac Surgery (RETROCAR)

Who this might be right for
Cardiac SurgeryCardiopulmonary BypassRenal Transplant Recipient
University Hospital, Bordeaux 93
Early research (Phase 1)Looking for participantsNCT06911320
What this trial is testing

Study of Bemnifosbuvir/Ruzasvir as a Fixed-dose Combination in Subjects With Normal or Severely Impaired Renal or Hepatic Function

Who this might be right for
Healthy Volunteer StudyHepatic ImpairmentRenal Impairment
Atea Pharmaceuticals, Inc. 28
Not applicableStudy completedNCT03192189
What this trial is testing

Development of a Decision-making Aid for Referring Severe Kidney Injury Patients for Nephrology Consultations

Who this might be right for
Chronic Kidney DiseasesAcute Kidney Injury
Centre Hospitalier Universitaire de Nīmes 319
Early research (Phase 1)Ended earlyNCT05487040
What this trial is testing

Measure the Amount of Study Medicine in Blood in Adult Participants With COVID-19 and Severe Kidney Disease

Who this might be right for
COVID-19
Pfizer 15
Not applicableStudy completedNCT04542954
What this trial is testing

Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience From the Middle East

Who this might be right for
Covid19Kidney Transplant InfectionRisk Factor, Cardiovascular+3 more
Hamid Al-Essa Organ Transplant Center 104
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