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Results for “Severe Systemic Sclerosis”

46 trials

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Showing 20 of 46 results

Very early researchLooking for participantsNCT07526350
What this trial is testing

MTS109 in Patients With Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusIdiopathic Inflammatory MyopathiesSystemic Sclerosis (SSc)+2 more
Shanghai Changzheng Hospital 15
Testing effectiveness (Phase 2)Study completedNCT00479934
What this trial is testing

Efficacy and Safety of Imatinib in Scleroderma

Who this might be right for
Scleroderma, LocalizedScleroderma, Systemic
University Hospital, Bordeaux 28
Not applicableLooking for participantsNCT07403188
What this trial is testing

A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101

Who this might be right for
Refractory Lupus NephritisMyasthaenia GravisStiff Person Syndrome+4 more
Kyverna Therapeutics 70
Large-scale testing (Phase 3)Ended earlyNCT02374320
What this trial is testing

Exparel as a Nerve Block for Severe Hand Pain

Who this might be right for
CREST SyndromePeripheral Vascular DiseaseRaynaud Disease+1 more
Jose Soberon, MD 13
Early research (Phase 1)Not Yet RecruitingNCT07676266
What this trial is testing

C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy

Who this might be right for
Multiple Sclerosis (MS)Myasthenia Gravis (MG)Neuromyelitis Optica Spectrum Disorder+3 more
The Affiliated Hospital of Qingdao University 18
Not applicableLooking for participantsNCT01793168
What this trial is testing

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Who this might be right for
Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more
Sanford Health 20,000
Testing effectiveness (Phase 2)WithdrawnNCT05098145
What this trial is testing

A Safety and Efficacy Study of FCR001 in Adults With Rapidly Progressive Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Diffuse Cutaneous Systemic Sclerosis
Talaris Therapeutics Inc.
Not applicableEnded earlyNCT01410903
What this trial is testing

Immunoadsorption in Patients With Severe Systemic Sclerosis

Who this might be right for
Systemic Scleroderma
GWT-TUD GmbH 1
Testing effectiveness (Phase 2)Ended earlyNCT03740724
What this trial is testing

FCX-013 Plus Veledimex for the Treatment of Moderate to Severe Localized Scleroderma (Morphea)

Who this might be right for
MorpheaScleroderma, LocalizedScleroderma
Castle Creek Biosciences, LLC. 1
Early research (Phase 1)Not Yet RecruitingNCT07544225
What this trial is testing

Study Investigating the Safety of Anti-CD19 CAR-T Cells Therapy Produced at Gustave Roussy for Adults With Severe and Refractory Systemic Autoimmune Rheumatic Diseases

Who this might be right for
Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)Sjogren's Disease With Dry Eyes+2 more
Gustave Roussy, Cancer Campus, Grand Paris 6
Testing effectiveness (Phase 2)Study completedNCT01393132
What this trial is testing

Comparative Study of Thymosin Beta 4 Eye Drops vs. Vehicle in the Treatment of Severe Dry Eye

Who this might be right for
Dry EyeSjogren's SyndromeGraft vs. Host Disease
Michigan Cornea Consultants, PC 9
Not applicableUnknownNCT01829126
What this trial is testing

Development and Prevention of Severe Heart Disease in Systemic Sclerosis

Who this might be right for
Systemic SclerosisCardiac DiseasesHeart Block+2 more
Gabriele Valentini 765
Not applicableNot Yet RecruitingNCT07717060
What this trial is testing

Extracellular Vesicle Dynamics Predicting Vascular Complications and Treatment Response in Systemic Sclerosis

Who this might be right for
Systemic SclerosisPulmonary Arterial HypertensionDigital Ulcers+1 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 60
Early research (Phase 1)Ended earlyNCT00849745
What this trial is testing

Nonmyeloablative Allo Stem Cell Transplant for Severe Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusSystemic Sclerosis
Duke University 4
Very early researchNot Yet RecruitingNCT07583030
What this trial is testing

A Clinical Study to Evaluate LVIVO-TaVec400 for the Treatment of Relapsed/Refractory Autoimmune Diseases

Who this might be right for
Relapsed/Refractory Systemic Lupus Erythematosus (r/r SLE)Relapsed/Refractory IgG4-Related Disease (r/r IgG4-RD)Progressive Multiple Sclerosis (PMS)+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 44
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06722105
What this trial is testing

Phase I/II Randomized Clinical Trial of Allogeneic Adipose Tissue-derived Mesenchymal Stromal Cells Systemic Infusion in Severe Systemic Sclerosis

Who this might be right for
Severe Systemic Sclerosis
Assistance Publique - Hôpitaux de Paris 18
Early research (Phase 1)Looking for participantsNCT06822881
What this trial is testing

CT1190B in the Treatment of Patients With Moderate to Severe Refractory Systemic Lupus Erythematosus (SLE) or Refractory/Progressive Systemic Sclerosis (SSc)

Who this might be right for
Systemic Lupus Erythematosus (SLE)Systemic Sclerosis (SSc)
Beijing GoBroad Hospital 27
Testing effectiveness (Phase 2)Study completedNCT00622895
What this trial is testing

Allogeneic Hematopoietic Cell Transplantation for Severe Systemic Sclerosis

Who this might be right for
Systemic SclerodermaSevere Systemic Sclerosis
Fred Hutchinson Cancer Center 3
Very early researchActive Not RecruitingNCT04380831
What this trial is testing

TBI Using IMRT and Cyclophosphamide Prior to Stem Cell Transplant for the Treatment of Severe Systemic Sclerosis

Who this might be right for
Systemic Scleroderma
City of Hope Medical Center 15
Not applicableUnknownNCT05635266
What this trial is testing

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Who this might be right for
Age-Related Macular DegenerationAllergiesAlpha-Gal Syndrome+44 more
Sanguine Biosciences 20,000
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