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Results for “Severe Systemic Sclerosis”

36 trials

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Showing 20 of 36 results

Testing effectiveness (Phase 2)Study completedNCT00622895
What this trial is testing

Allogeneic Hematopoietic Cell Transplantation for Severe Systemic Sclerosis

Who this might be right for
Systemic SclerodermaSevere Systemic Sclerosis
Fred Hutchinson Cancer Center 3
Testing effectiveness (Phase 2)Looking for participantsNCT06655896
What this trial is testing

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Scleroderma, Diffuse
Novartis Pharmaceuticals 96
Large-scale testing (Phase 3)Study completedNCT00114530
What this trial is testing

Scleroderma: Cyclophosphamide or Transplantation

Who this might be right for
Scleroderma, SystemicSclerosisAutoimmune Disease
National Institute of Allergy and Infectious Diseases (NIAID) 75
Testing effectiveness (Phase 2)WithdrawnNCT05098145
What this trial is testing

A Safety and Efficacy Study of FCR001 in Adults With Rapidly Progressive Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Diffuse Cutaneous Systemic Sclerosis
Talaris Therapeutics Inc.
Not applicableStudy completedNCT03941184
What this trial is testing

Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity

Who this might be right for
SCADAddison DiseaseAnkylosing Spondylitis+26 more
Mayo Clinic 114
Large-scale testing (Phase 3)Ended earlyNCT02374320
What this trial is testing

Exparel as a Nerve Block for Severe Hand Pain

Who this might be right for
CREST SyndromePeripheral Vascular DiseaseRaynaud Disease+1 more
Jose Soberon, MD 13
Very early researchLooking for participantsNCT04380831
What this trial is testing

TBI Using IMRT and Cyclophosphamide Prior to Stem Cell Transplant for the Treatment of Severe Systemic Sclerosis

Who this might be right for
Systemic Scleroderma
City of Hope Medical Center 15
Early research (Phase 1)Looking for participantsNCT07115745
What this trial is testing

Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases

Who this might be right for
Refractory Autoimmune Diseases
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 125
Early research (Phase 1)Looking for participantsNCT05869955
What this trial is testing

CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)

Who this might be right for
Systemic Lupus ErythematosusIdiopathic Inflammatory MyopathySystemic Sclerosis+1 more
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 270
Not applicableLooking for participantsNCT05635266
What this trial is testing

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Who this might be right for
Age-Related Macular DegenerationAllergiesAlpha-Gal Syndrome+44 more
Sanguine Biosciences 20,000
Very early researchLooking for participantsNCT07000682
What this trial is testing

The Clinical Study on the Treatment of SSc With UTAA91 Injection.

Who this might be right for
Systemic Sclerosis (SSc)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 24
Large-scale testing (Phase 3)Study completedNCT00025818
What this trial is testing

Six Month Clinical Research Study for Patients With Moderate or Severe Dry Eye Syndrome

Who this might be right for
Keratoconjunctivitis SiccaSjogren's SyndromeLupus Erythematosus, Systemic+2 more
Allergan 290
Testing effectiveness (Phase 2)WithdrawnNCT01047072
What this trial is testing

Low-Dose Conditioning Followed by Donor Stem Cell Transplant in Treating Patients With Severe Systemic Sclerosis

Who this might be right for
Systemic Scleroderma
Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
Very early researchNot Yet RecruitingNCT06982534
What this trial is testing

Clinical Study on the Treatment of Systemic Sclerosis With UTAA91 Injection.

Who this might be right for
Systemic Sclerosis (SSc)
PersonGen BioTherapeutics (Suzhou) Co., Ltd. 24
Early research (Phase 1)Looking for participantsNCT06249438
What this trial is testing

C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy

Who this might be right for
Systemic Lupus Erythematosus (SLE)Immune-mediated Necrotizing Myopathy (IMNM)Neuromyelitis Optica Spectrum Disorders (NMOSD)+3 more
RenJi Hospital 30
Not applicableUnknownNCT01829126
What this trial is testing

Development and Prevention of Severe Heart Disease in Systemic Sclerosis

Who this might be right for
Systemic SclerosisCardiac DiseasesHeart Block+2 more
Gabriele Valentini 765
Early research (Phase 1)Active Not RecruitingNCT06544330
What this trial is testing

SYNCAR-001 + STK-009 Without Conditioning Chemotherapy (Lymphodepletion) in Subjects With Severe, Refractory Systemic Autoimmune Rheumatic Disease

Who this might be right for
Systemic Lupus ErythematosusLupus NephritisSystemic Sclerosis
Synthekine 48
Early research (Phase 1)Ended earlyNCT00849745
What this trial is testing

Nonmyeloablative Allo Stem Cell Transplant for Severe Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusSystemic Sclerosis
Duke University 4
Not applicableEnded earlyNCT01410903
What this trial is testing

Immunoadsorption in Patients With Severe Systemic Sclerosis

Who this might be right for
Systemic Scleroderma
GWT-TUD GmbH 1
Testing effectiveness (Phase 2)Ended earlyNCT03740724
What this trial is testing

FCX-013 Plus Veledimex for the Treatment of Moderate to Severe Localized Scleroderma (Morphea)

Who this might be right for
MorpheaScleroderma, LocalizedScleroderma
Castle Creek Biosciences, LLC. 1
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