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Results for “Severe Systemic Sclerosis”

43 trials

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Showing 20 of 43 results

Post-approval studies (Phase 4)WithdrawnNCT01497743
What this trial is testing

Probiotics in Patients With Moderate-to-severe Distention/ Bloating From Systemic Sclerosis

Who this might be right for
Scleroderma
University of Michigan
Not applicableLooking for participantsNCT04334031
What this trial is testing

Deployment o the Multidisciplinary Prospective Cohort Imminent

Who this might be right for
Chronic Inflammatory DiseaseAngioedemaSevere Asthma+6 more
University Hospital, Lille 2,200
Testing effectiveness (Phase 2)Study completedNCT00479934
What this trial is testing

Efficacy and Safety of Imatinib in Scleroderma

Who this might be right for
Scleroderma, LocalizedScleroderma, Systemic
University Hospital, Bordeaux 28
Large-scale testing (Phase 3)Study completedNCT03957681
What this trial is testing

KHK4827 in Patients With Systemic Sclerosis

Who this might be right for
Moderate to Severe Systemic Sclerosis
Kyowa Kirin Co., Ltd. 100
Very early researchLooking for participantsNCT07526350
What this trial is testing

MTS109 in Patients With Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusIdiopathic Inflammatory MyopathiesSystemic Sclerosis (SSc)+2 more
Shanghai Changzheng Hospital 15
Not applicableStudy completedNCT07469865
What this trial is testing

Efficacy and Safety of 20% and 100% Autologous Serum Eye Drops in Patients With Severe Dry Eye Disease (AST)

Who this might be right for
Dry Eye Disease
University Hospital, Ghent 46
Testing effectiveness (Phase 2)Study completedNCT00622895
What this trial is testing

Allogeneic Hematopoietic Cell Transplantation for Severe Systemic Sclerosis

Who this might be right for
Systemic SclerodermaSevere Systemic Sclerosis
Fred Hutchinson Cancer Center 3
Testing effectiveness (Phase 2)Ended earlyNCT03740724
What this trial is testing

FCX-013 Plus Veledimex for the Treatment of Moderate to Severe Localized Scleroderma (Morphea)

Who this might be right for
MorpheaScleroderma, LocalizedScleroderma
Castle Creek Biosciences, LLC. 1
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06722105
What this trial is testing

Phase I/II Randomized Clinical Trial of Allogeneic Adipose Tissue-derived Mesenchymal Stromal Cells Systemic Infusion in Severe Systemic Sclerosis

Who this might be right for
Severe Systemic Sclerosis
Assistance Publique - Hôpitaux de Paris 18
Testing effectiveness (Phase 2)Study completedNCT00379431
What this trial is testing

A Protocol Based Treatment for Early and Severe Systemic Sclerosis With (Anti-CD20), Rituximab

Who this might be right for
Early and Severe Systemic Sclerosis
University Hospital, Ghent 9
Early research (Phase 1)Ended earlyNCT00849745
What this trial is testing

Nonmyeloablative Allo Stem Cell Transplant for Severe Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusSystemic Sclerosis
Duke University 4
Testing effectiveness (Phase 2)WithdrawnNCT05098145
What this trial is testing

A Safety and Efficacy Study of FCR001 in Adults With Rapidly Progressive Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Diffuse Cutaneous Systemic Sclerosis
Talaris Therapeutics Inc.
Early research (Phase 1)Not Yet RecruitingNCT07544225
What this trial is testing

Study Investigating the Safety of Anti-CD19 CAR-T Cells Therapy Produced at Gustave Roussy for Adults With Severe and Refractory Systemic Autoimmune Rheumatic Diseases

Who this might be right for
Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)Sjogren's Disease With Dry Eyes+2 more
Gustave Roussy, Cancer Campus, Grand Paris 6
Large-scale testing (Phase 3)Study completedNCT00114530
What this trial is testing

Scleroderma: Cyclophosphamide or Transplantation

Who this might be right for
Scleroderma, SystemicSclerosisAutoimmune Disease
National Institute of Allergy and Infectious Diseases (NIAID) 75
Not applicableLooking for participantsNCT07470151
What this trial is testing

Clinical Study of EVM18001 in the Treatment of Refractory Autoimmune Diseases

Who this might be right for
System Lupus Erythematosus(SLE)SclerodermaMyasthenia Gravis (MG)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 12
Not applicableLooking for participantsNCT07403188
What this trial is testing

A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101

Who this might be right for
Refractory Lupus NephritisMyasthaenia GravisStiff Person Syndrome+4 more
Kyverna Therapeutics 70
Not applicableStudy completedNCT03941184
What this trial is testing

Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity

Who this might be right for
SCADAddison DiseaseAnkylosing Spondylitis+26 more
Mayo Clinic 114
Testing effectiveness (Phase 2)Looking for participantsNCT06655896
What this trial is testing

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis

Who this might be right for
Scleroderma, Diffuse
Novartis Pharmaceuticals 96
Early research (Phase 1)Looking for participantsNCT06708845
What this trial is testing

US Zamto-cel Autoimmune Diseases

Who this might be right for
Lupus NephritisSystemic Lupus ErythematosusSystemic Sclerosis (SSc)+1 more
Miltenyi Biomedicine GmbH 48
Early research (Phase 1)Looking for participantsNCT07115745
What this trial is testing

Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases

Who this might be right for
Refractory Autoimmune Diseases
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 125
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