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Results for “Solid Tumor Leptomeningeal Metastasis”

39 trials

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Showing 20 of 39 results

Testing effectiveness (Phase 2)Study completedNCT04343573
What this trial is testing

Proton Craniospinal Radiation Therapy vs. Partial Photon Radiation Therapy for Leptomeningeal Metastasis From Solid Tumors

Who this might be right for
Leptomeningeal Metastases
Memorial Sloan Kettering Cancer Center 102
Early research (Phase 1)Study completedNCT00854867
What this trial is testing

Study to Demonstrate the Safety of WBR Administered at the Same Time as Intrathecal Liposomal Cytarabine (DepoCyte®) Versus Intrathecal Liposomal Cytarabine (DepoCyte®) Administered After WBR for the Treatment of Solid Tumour Neoplastic Meningitis in Patients With or Without Brain Metastasis.

Who this might be right for
Solid Tumour Neoplastic MeningitisBrain Metastases
Mundipharma Research Limited 18
Testing effectiveness (Phase 2)Looking for participantsNCT07098806
What this trial is testing

Multiple Dose Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases

Who this might be right for
Leptomeningeal Metastasis
Cerenome 24
Not applicableEnrolling By InvitationNCT06705049
What this trial is testing

Retrospective Study on Leptomeningeal Metastasis of Solid Tumors

Who this might be right for
Leptomeningeal Metastasis
Shanghai Zhongshan Hospital 107
Not applicableWithdrawnNCT01438021
What this trial is testing

Continuous Intraventricular Methotrexate in Treating Patients With Leptomeningeal Disease

Who this might be right for
Leptomeningeal Metastases
City of Hope Medical Center
Testing effectiveness (Phase 2)Looking for participantsNCT06910761
What this trial is testing

Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell Carcinoma+2 more
City of Hope Medical Center 35
Testing effectiveness (Phase 2)Looking for participantsNCT06518057
What this trial is testing

Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell Carcinoma+2 more
University of Washington 22
Very early researchNot Yet RecruitingNCT07656103
What this trial is testing

QH101 Cell Injection in Patients With Brain, Brain (Spinal) Meninges, and Spinal Cord Metastatic Malignant Solid Tumors

Who this might be right for
Brain MetastasisMeningeal MetastasisSpinal Cord Metastasis
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 7
Early research (Phase 1)Active Not RecruitingNCT06724926
What this trial is testing

Concurrent Azeliragon With Craniospinal Irradiation

Who this might be right for
Solid TumorHigh-grade GliomaLeptomeningeal Metastasis
NYU Langone Health 21
Testing effectiveness (Phase 2)Study completedNCT03082144
What this trial is testing

Concurrent Involved-field Radiotherapy and Intrathecal Chemotherapy for Leptomeningeal Metastases From Solid Tumors

Who this might be right for
Leptomeningeal Metastasis
The First Hospital of Jilin University 53
Early research (Phase 1)Active Not RecruitingNCT03423628
What this trial is testing

Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

Who this might be right for
Recurrent Glioblastoma MultiformePrimary Glioblastoma MultiformeBrain Neoplasms, Malignant+1 more
AstraZeneca 159
Not applicableUnknownNCT05305885
What this trial is testing

Intra-pemetrexed Alone or Combined With Concurrent Radiotherapy for Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis
The First Hospital of Jilin University 100
Testing effectiveness (Phase 2)Active Not RecruitingNCT06762080
What this trial is testing

Intrathecal Combination of Programmed Death-1 (PD-1)/Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4) Bispecific Antibody and Pemetrexed for Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis
Guangzhou Medical University 36
Early research (Phase 1)Looking for participantsNCT05112549
What this trial is testing

Intrathecal Application of PD1 Antibody in Metastatic Solid Tumors With Leptomeningeal Disease (IT-PD1/ NOA 26)

Who this might be right for
Leptomeningeal Disease
University Hospital Tuebingen 46
Early research (Phase 1)Ended earlyNCT00512460
What this trial is testing

RTA 744 Injection in Patients With Leptomeningeal Disease

Who this might be right for
Neoplastic MeningitisSolid TumorLymphoma+2 more
M.D. Anderson Cancer Center 7
Not applicableStudy completedNCT02071056
What this trial is testing

Circulating Tumor DNA in Cerebrospinal Fluid as an Early Biomarker of Leptomeningeal Metastasis (LM)

Who this might be right for
Leptomeningeal Metastasis
Dartmouth-Hitchcock Medical Center 5
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07833657
What this trial is testing

Combined Intrathecal and Systemic Therapy With Trastuzumab Rezetecan for Leptomeningeal Metastases

Who this might be right for
Leptomeningeal MetastasesSolid Tumors
Jiuda Zhao 28
Testing effectiveness (Phase 2)Active Not RecruitingNCT06462222
What this trial is testing

Immune Checkpoint Inhibitor Combined With Pemetrexed Intrathecal Injection for Leptomeningeal Metastasis From Solid Tumors

Who this might be right for
Leptomeningeal Metastasis
Guangzhou Medical University 45
Early research (Phase 1)UnknownNCT00003073
What this trial is testing

Chemotherapy in Treating Young Patients With Recurrent or Refractory Meningeal Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsLeukemiaLymphoma+1 more
Pacira Pharmaceuticals, Inc 15
Post-approval studies (Phase 4)Study completedNCT00029523
What this trial is testing

DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid Tumor

Who this might be right for
Meningeal Neoplasms
Pacira Pharmaceuticals, Inc 100
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