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Results for “Solid Tumour Neoplastic Meningitis”

30 trials

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Showing 20 of 30 results

Testing effectiveness (Phase 2)Looking for participantsNCT06762080
What this trial is testing

Intrathecal Combination of Programmed Death-1 (PD-1)/Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4) Bispecific Antibody and Pemetrexed for Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis
Guangzhou Medical University 36
Early research (Phase 1)Study completedNCT00854867
What this trial is testing

Study to Demonstrate the Safety of WBR Administered at the Same Time as Intrathecal Liposomal Cytarabine (DepoCyte®) Versus Intrathecal Liposomal Cytarabine (DepoCyte®) Administered After WBR for the Treatment of Solid Tumour Neoplastic Meningitis in Patients With or Without Brain Metastasis.

Who this might be right for
Solid Tumour Neoplastic MeningitisBrain Metastases
Mundipharma Research Limited 18
Testing effectiveness (Phase 2)Study completedNCT03507244
What this trial is testing

Concurrent Intrathecal-pemetrexed and Involved-field Radiotherapy for Leptomeningeal Metastasis From Solid Tumors

Who this might be right for
Leptomeningeal Metastasis
The First Hospital of Jilin University 34
Early research (Phase 1)Active Not RecruitingNCT04192981
What this trial is testing

GDC-0084 With Radiation Therapy for People With PIK3CA-Mutated Solid Tumor Brain Metastases or Leptomeningeal Metastases

Who this might be right for
Brain MetastasesLeptomeningeal Metastasis
Memorial Sloan Kettering Cancer Center 21
Very early researchStudy completedNCT00424242
What this trial is testing

Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal Metastases

Who this might be right for
Brain and Central Nervous System TumorsChronic Myeloproliferative DisordersLeukemia+8 more
Northwestern University 15
Not applicableStudy completedNCT06592092
What this trial is testing

Clinical Study of QH104 Cell Injection for the Treatment of Meningeal Metastases of B7H3+ Solid Tumors

Who this might be right for
Solid TumorMeningeal Metastasis
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 3
Early research (Phase 1)Looking for participantsNCT06724926
What this trial is testing

Concurrent Azeliragon With Craniospinal Irradiation

Who this might be right for
Solid TumorHigh-grade GliomaLeptomeningeal Metastasis
NYU Langone Health 32
Testing effectiveness (Phase 2)Ended earlyNCT04729348
What this trial is testing

Pembrolizumab And Lenvatinib In Leptomeningeal Metastases

Who this might be right for
Solid TumorSolid Tumor, AdultLeptomeningeal Metastasis
Massachusetts General Hospital 10
Testing effectiveness (Phase 2)Looking for participantsNCT06518057
What this trial is testing

Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell Carcinoma+2 more
University of Washington 22
Testing effectiveness (Phase 2)Looking for participantsNCT06809530
What this trial is testing

Intrathecal Dual Checkpoint Inhibitor (PD-1 and CTLA-4) in Combination With Pemetrexed for Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal MetastasisPemetrexedPD-1 Inhibitor+2 more
Guangzhou Medical University 34
Testing effectiveness (Phase 2)Study completedNCT04343573
What this trial is testing

Proton Craniospinal Radiation Therapy vs. Partial Photon Radiation Therapy for Leptomeningeal Metastasis From Solid Tumors

Who this might be right for
Leptomeningeal Metastases
Memorial Sloan Kettering Cancer Center 102
Testing effectiveness (Phase 2)WithdrawnNCT04315246
What this trial is testing

177Lu-DTPA-Omburtamab Radioimmunotherapy for Leptomeningeal Metastasis From Solid Tumors (Breast, NSCLC, Malignant Melanoma)

Who this might be right for
Leptomeningeal MetastasisSolid Tumor, Adult
Y-mAbs Therapeutics
Testing effectiveness (Phase 2)Ended earlyNCT00005812
What this trial is testing

Temozolomide in Treating Patients With Leptomeningeal Metastases From a Solid Tumor or Lymphoma

Who this might be right for
Brain TumorsCentral Nervous System TumorsLeptomeningeal Metastases
Dartmouth-Hitchcock Medical Center 12
Not applicableUnknownNCT05305885
What this trial is testing

Intra-pemetrexed Alone or Combined With Concurrent Radiotherapy for Leptomeningeal Metastasis

Who this might be right for
Leptomeningeal Metastasis
The First Hospital of Jilin University 100
Early research (Phase 1)UnknownNCT00003073
What this trial is testing

Chemotherapy in Treating Young Patients With Recurrent or Refractory Meningeal Leukemia, Lymphoma, or Solid Tumors

Who this might be right for
Brain and Central Nervous System TumorsLeukemiaLymphoma+1 more
Pacira Pharmaceuticals, Inc 15
Testing effectiveness (Phase 2)Looking for participantsNCT06910761
What this trial is testing

Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Lung Non-Small Cell Carcinoma+2 more
City of Hope Medical Center 35
Early research (Phase 1)Ended earlyNCT00512460
What this trial is testing

RTA 744 Injection in Patients With Leptomeningeal Disease

Who this might be right for
Neoplastic MeningitisSolid TumorLymphoma+2 more
M.D. Anderson Cancer Center 7
Testing effectiveness (Phase 2)Study completedNCT00005811
What this trial is testing

Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment

Who this might be right for
AIDS-related Diffuse Large Cell LymphomaAIDS-related Diffuse Mixed Cell LymphomaAIDS-related Diffuse Small Cleaved Cell Lymphoma+17 more
National Cancer Institute (NCI) 77
Testing effectiveness (Phase 2)Study completedNCT03082144
What this trial is testing

Concurrent Involved-field Radiotherapy and Intrathecal Chemotherapy for Leptomeningeal Metastases From Solid Tumors

Who this might be right for
Leptomeningeal Metastasis
The First Hospital of Jilin University 53
Not applicableWithdrawnNCT01438021
What this trial is testing

Continuous Intraventricular Methotrexate in Treating Patients With Leptomeningeal Disease

Who this might be right for
Leptomeningeal Metastases
City of Hope Medical Center
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