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Results for “Sphingosine 1-phosphate”

22 trials

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Showing 20 of 22 results

Testing effectiveness (Phase 2)Study completedNCT07335952
What this trial is testing

Proximod, a Selective Sphingosine-1-phosphate Receptor 1 Modulator in Patients With Moderate-to-severe Active Rheumatoid Arthritis: a Double-blind, Randomised, Placebo-controlled, Phase 2 Trial.

Who this might be right for
Rheumatoid Arthritis
Peking University People's Hospital 179
Early research (Phase 1)Study completedNCT01466322
What this trial is testing

Assess the Relative Bioavailability of Different Formulations of GSK2018682, a Sphingosine-1-phosphate Receptor Subtype 1 Agonist, in Healthy Volunteers.

Who this might be right for
Multiple Sclerosis, Relapsing-Remitting
GlaxoSmithKline 16
Not applicableUnknownNCT06349226
What this trial is testing

Identification of Biomarkers and Molecular Targets Involved on Intervertebral Disc Degeneration and Discogenic Pain

Who this might be right for
Intervertebral Disc DegenerationDiscogenic PainDiscogenic Disease
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico 160
Not applicableUnknownNCT04134351
What this trial is testing

Sphingosine-1-phosphate in Asthma

Who this might be right for
Asthma
Guy's and St Thomas' NHS Foundation Trust 12
Not applicableStudy completedNCT06930430
What this trial is testing

IL-1β and S1P Levels After Periodontal Therapy: A Split-Mouth Study

Who this might be right for
Sphingosine 1-phosphateInterleukin 1-betaGingival Crevicular Fluid+2 more
Ondokuz Mayıs University 17
Testing effectiveness (Phase 2)Study completedNCT03338998
What this trial is testing

Efficacy, Safety and Tolerability of BAF312 Compared to Placebo in Patients With Intracerebral Hemorrhage (ICH).

Who this might be right for
Hemorrhagic StrokeIntracerebral Hemorrhage (ICH)
Novartis Pharmaceuticals 32
Not applicableUnknownNCT06348693
What this trial is testing

Development of Therapeutic Approaches Modulating Molecular Targets Implicated on Cancer Stem Cell-related Aggressiveness

Who this might be right for
GlioblastomaGliomaGlioma Glioblastoma Multiforme
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico 400
Not applicableStudy completedNCT02981433
What this trial is testing

Vulvodynia: Identification of Potential Relevant Biomarkers

Who this might be right for
Vulvodynia
St. Louis University 2
Not applicableStudy completedNCT02139696
What this trial is testing

Sphingosine-1 Phosphate -Receptor Targeting and Microglial Activation

Who this might be right for
Multiple Sclerosis
Turku University Hospital 10
Not applicableLooking for participantsNCT05828901
What this trial is testing

Predicting Disease Activity and Rebound Risk in MS Patients Treated With Sphingosine-1-phosphate Receptor Modulators (S1PRM)

Who this might be right for
Multiple Sclerosis
Insel Gruppe AG, University Hospital Bern 60
Not applicableStudy completedNCT02973854
What this trial is testing

Activation of the Sphingosine-1-phosphate (S1P) to S1P1 Receptor Subtype (S1PR1) Axis in Patients With Endometriosis: Identification of Potential Relevant Biomarkers to Diagnose and Treat

Who this might be right for
Endometriosis
St. Louis University 80
Not applicableUnknownNCT03473119
What this trial is testing

Evaluation of Plasma Sphingosine-1-Phosphate as A Diagnostic and Prognostic Biomarkers of Community-Acquired Pneumonia

Who this might be right for
PneumoniaChronic Obstructive Pulmonary DiseaseAsthma
Taipei Medical University WanFang Hospital 600
Not applicableNot Yet RecruitingNCT07250880
What this trial is testing

Evaluation of Serum Ceramides C16, C24, and Sphingosine-1-Phosphate (S1P) in Patients With Acne Vulgaris

Who this might be right for
Acne Vulgaris
Sohag University 80
Not applicableNot Yet RecruitingNCT05953402
What this trial is testing

Ozanimod in Pregnant Women With Ulcerative Colitis and Their Offspring

Who this might be right for
Ulcerative Colitis
Bristol-Myers Squibb 1,182
Not applicableTemporarily pausedNCT04657146
What this trial is testing

Longitudinal Assessment of Marrow and Blood in Patients With Glioblastoma

Who this might be right for
Glioblastoma
Duke University 40
Not applicableStudy completedNCT03003845
What this trial is testing

S1P1 Receptor Subtype (S1PR1) Axis in Patients With Interstitial Cystitis (IC) Pain

Who this might be right for
Interstitial Cystitis
St. Louis University 21
Testing effectiveness (Phase 2)Active Not RecruitingNCT05156125
What this trial is testing

VTX002 Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Colitis, Ulcerative
Oppilan Pharma Ltd 213
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06862960
What this trial is testing

Ozanimod in Patients With Alzheimer's Disease

Who this might be right for
Alzheimer Disease
ChenXiaoChun 40
Not applicableLooking for participantsNCT06161376
What this trial is testing

Role of Urinary Sphingosine 1-Phosphate as a Biomarker for Detrusor Hyperactivity in Multiple Sclerosis

Who this might be right for
Multiple Sclerosis
University Hospital, Toulouse 400
Not applicableUnknownNCT01776489
What this trial is testing

Evaluation of the Sphingolipid Metabolite S1P as a Novel Biomarker in Food Allergy

Who this might be right for
Food AllergyAnaphylaxis
Medical University of Vienna 70
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