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Results for “Transthyretin Amyloidosis With Polyneuropathy”

39 trials

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Showing 20 of 39 results

Not applicableLooking for participantsNCT06845644
What this trial is testing

Longitudinal Quantitative Neuromuscular MRI in Neuropathic Patients

Who this might be right for
Charcot-Marie-Tooth Neuropathy Type 1AHereditary Transthyretin Amyloid NeuropathyAcquired Demyelinating Neuropathy
Assistance Publique Hopitaux De Marseille 120
Post-approval studies (Phase 4)Ended earlyNCT04306510
What this trial is testing

Characterize Adverse Events Occurring Within One Day of TEGSEDI Administration to Adult Participants With hATTR-PN

Who this might be right for
Hereditary Transthyretin Amyloidosis With Polyneuropthy
Akcea Therapeutics 8
Not applicableStudy completedNCT05560555
What this trial is testing

Retrospective Study Collecting Neurological Follow-up of Hereditary Transthyretin Amyloidosis (ATTRv) Patients Included in B3461028 and B3461045.

Who this might be right for
Hereditary Transthyretin Amyloidosis (ATTRv)Polyneuropathy
Pfizer 5
Post-approval studies (Phase 4)Looking for participantsNCT06940336
What this trial is testing

To Evaluate the Efficacy and Safety of Tafamidis Meglumine Soft Capsules in the Treatment of Adult Patients With Transthyretin Amyloid Polyneuropathy

Who this might be right for
Transthyretin Amyloid Polyneuropathy
Qilu Pharmaceutical Co., Ltd. 15
Large-scale testing (Phase 3)Not Yet RecruitingNCT07116473
What this trial is testing

To Evaluate the Long-term Safety and Tolerability of Acoramidis in Participants With Newly Diagnosed ATTR-CM (ACT-EARLY OLE)

Who this might be right for
Amyloidosis in Transthyretin (TTR)Amyloidosis, FamilialAmyloid Cardiomyopathy+7 more
Eidos Therapeutics, a BridgeBio company 250
Large-scale testing (Phase 3)Study completedNCT01435655
What this trial is testing

The Effect Of Tafamidis For The Transthyretin Amyloid Polyneuropathy Patients With V30M Or Non-V30M Transthyretin

Who this might be right for
Transthyretin Familial Amyloid Polyneuropathy
Pfizer 10
Large-scale testing (Phase 3)Study completedNCT01737398
What this trial is testing

Efficacy and Safety of Inotersen in Familial Amyloid Polyneuropathy

Who this might be right for
FAPFamilial Amyloid PolyneuropathyTTR+2 more
Ionis Pharmaceuticals, Inc. 173
Not applicableLooking for participantsNCT07654855
What this trial is testing

Long-term Safety of Eplontersen Treated aTTR Patients and in Liver Transplant and Severely Hepatic Impaired Subpopulations

Who this might be right for
Transthyretin AmyloidosisTransthyretin Amyloidosis With CardiomyopathyTransthyretin Amyloidosis With Polyneuropathy
AstraZeneca 320
Not applicableLooking for participantsNCT06465810
What this trial is testing

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

Who this might be right for
Transthyretin AmyloidosisATTR-CMATTRv-PN+3 more
AstraZeneca 1,850
Not applicableStudy completedNCT06365593
What this trial is testing

HATTR Polyneuropathy in Russia

Who this might be right for
Hereditary Transthyretin Amyloidosis
AstraZeneca 100
Large-scale testing (Phase 3)WithdrawnNCT04418024
What this trial is testing

Efficacy and Safety of AG10 in Subjects with Transthyretin Amyloid Polyneurophathy

Who this might be right for
Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy
Eidos Therapeutics, a BridgeBio company
Testing effectiveness (Phase 2)Study completedNCT00630864
What this trial is testing

The Effects of Fx-1006A on Transthyretin Stabilization and Clinical Outcome Measures in Patients With Non-V30M Transthyretin Amyloidosis

Who this might be right for
Transthyretin-associated Amyloidosis With Polyneuropathy
Pfizer 21
Testing effectiveness (Phase 2)UnknownNCT06539208
What this trial is testing

A Phase I/IIa，Open-label, Single Ascending Dose and Dose-expansion Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of YOLT-201 in Patients With Transthyretin Amyloidosis Polyneuropathy (ATTR-PN) or Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)

Who this might be right for
Transthyretin Amyloidosis PolyneuropathyTransthyrexin Amyloidosis Cardiomyopathy
YolTech Therapeutics Co., Ltd 31
Large-scale testing (Phase 3)Study completedNCT00409175
What this trial is testing

Safety and Efficacy Study of Fx-1006A in Patients With Familial Amyloidosis

Who this might be right for
Familial Amyloid Polyneuropathy
Pfizer 128
Not applicableStudy completedNCT01604122
What this trial is testing

Burden of Disease Study In Patients With Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP) orTransthyretin Cardiomyopathy (TTR-CM) And Caregivers

Who this might be right for
Transthyretin Familial Amyloidosis Polyneuropathy (TTR-FAP)Transthyretin Cardiomyopathy (TTR-CM)Familial Amyloid Cardiomyopathy+1 more
Pfizer 1
Not applicableApproved For MarketingNCT02939820
What this trial is testing

Expanded Access Protocol of Patisiran for Patients With Hereditary ATTR Amyloidosis (hATTR)

Who this might be right for
TTR-mediated AmyloidosisAmyloidosis, HereditaryAmyloid Neuropathies, Familial+3 more
Alnylam Pharmaceuticals
Large-scale testing (Phase 3)Study completedNCT00791492
What this trial is testing

An Extension of Study Fx-005 Evaluating Long-Term Safety And Clinical Outcomes Of Fx-1006A In Patients With Transthyretin Amyloid Polyneuropathy

Who this might be right for
Familial Amyloid PolyneuropathyATTR-PN
Pfizer 86
Not applicableActive Not RecruitingNCT04850105
What this trial is testing

A Non-interventional Cohort Safety Study of Patients With hATTR-PN

Who this might be right for
Hereditary Transthyretin Amyloidosis With Polyneuropthy
Akcea Therapeutics 202
Testing effectiveness (Phase 2)Study completedNCT01961921
What this trial is testing

The Study of ALN-TTR02 (Patisiran) for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Patients Who Have Already Been Treated With ALN-TTR02 (Patisiran)

Who this might be right for
TTR-mediated Amyloidosis
Alnylam Pharmaceuticals 27
Not applicableActive Not RecruitingNCT06360289
What this trial is testing

Observational Study of Neurofilament Light Chain (NfL) as a Biomarker in Asymptomatic Carriers of the Transthyretin (TTR) Variants and Patients With Hereditary Transthyretin-mediated (hATTR) Amyloidosis With Polyneuropathy

Who this might be right for
Hereditary Amyloidosis, Transthyretin-RelatedAsymptomatic Carrier State
Alnylam Pharmaceuticals 346
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