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Results for “Ulcerative Colitis, Active Severe”

176 trials

Showing 20 of 176 results

Not applicableStudy completedNCT05791526
What this trial is testing

An Observational Study to Assess Change in Disease Activity and Adverse Events of Rinvoq in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Japan

Who this might be right for
Ulcerative Colitis
AbbVie 308
Testing effectiveness (Phase 2)Active Not RecruitingNCT05242484
What this trial is testing

Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Colitis, Ulcerative
Janssen Research & Development, LLC 577
Testing effectiveness (Phase 2)Study completedNCT02337608
What this trial is testing

Efficacy and Safety of GLPG1205 in Subjects With Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Galapagos NV 64
Large-scale testing (Phase 3)Ended earlyNCT04985968
What this trial is testing

The Efficacy and Safety of Cobitolimod in Participants With Moderate to Severe Active Left-Sided Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
InDex Pharmaceuticals 171
Large-scale testing (Phase 3)Study completedNCT00853099
What this trial is testing

Adalimumab in Japanese Subjects With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
AbbVie (prior sponsor, Abbott) 274
Large-scale testing (Phase 3)Study completedNCT03945188
What this trial is testing

Etrasimod Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Arena Pharmaceuticals 433
Testing effectiveness (Phase 2)Looking for participantsNCT06029972
What this trial is testing

Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Gilead Sciences 176
Large-scale testing (Phase 3)Active Not RecruitingNCT03596645
What this trial is testing

Assess the Efficacy and Safety of Golimumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Colitis, Ulcerative
Janssen Research & Development, LLC 84
Testing effectiveness (Phase 2)Ended earlyNCT03298022
What this trial is testing

Efficacy&Safety of ALTB-168 in Patients With Moderate to Severe Active,Anti-TNF Alpha and/or Anti-integrin Refractory UC

Who this might be right for
Ulcerative Colitis
AltruBio Inc. 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT05611671
What this trial is testing

Evaluate MORF-057 in Adults With Moderately to Severely Active UC

Who this might be right for
Inflammatory Bowel DiseasesColitis, Ulcerative
Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company) 280
Testing effectiveness (Phase 2)Study completedNCT03675477
What this trial is testing

A Phase II Study in Patients With Moderate to Severe Active Ulcerative Colitis.

Who this might be right for
Ulcerative Colitis
Reistone Biopharma Company Limited 164
Large-scale testing (Phase 3)Active Not RecruitingNCT05782907
What this trial is testing

Study to Assess Adverse Events, Change in Disease Activity, and How Oral Upadacitinib Moves Through the Body of Pediatric Participants With Moderately to Severely Active Ulcerative Colitis.

Who this might be right for
Ulcerative Colitis
AbbVie 122
Testing effectiveness (Phase 2)Looking for participantsNCT06254950
What this trial is testing

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Takeda 207
Testing effectiveness (Phase 2)Study completedNCT05377580
What this trial is testing

Evaluate IBI112 in the Treatment of Moderate to Severe Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis (UC)
Innovent Biologics (Suzhou) Co. Ltd. 150
Testing effectiveness (Phase 2)Study completedNCT03662542
What this trial is testing

Efficacy and Safety of Combination Therapy With Guselkumab and Golimumab in Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Colitis, Ulcerative
Janssen Research & Development, LLC 214
Not applicableLooking for participantsNCT06469424
What this trial is testing

An Active Surveillance, Post-Authorization Study to Characterize the Safety of Tofacitinib in Patients With Moderately to Severely Active Ulcerative Colitis in the Real-World Setting Using Data From the United Registries for Clinical Assessment and Research (UR-CARE) in the European Union (EU)

Who this might be right for
Ulcerative Colitis
Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa 104
Very early researchNot Yet RecruitingNCT06853522
What this trial is testing

HucMSCs Exosomes for the Treatment of Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis (UC)
Shanghai East Hospital 40
Testing effectiveness (Phase 2)Active Not RecruitingNCT06257875
What this trial is testing

Assess Adverse Events and Change in Disease Activity From Intravenous (IV) and Subcutaneous (SC) Lutikizumab in Adult Participants With Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
AbbVie 156
Testing effectiveness (Phase 2)Looking for participantsNCT07229950
What this trial is testing

Clinical Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of HRS-7085 Tablets in Patients With Inflammatory Bowel Disease

Who this might be right for
Adult Patients With Moderately to Severely Active Ulcerative Colitis
Shandong Suncadia Medicine Co., Ltd. 66
Testing effectiveness (Phase 2)Active Not RecruitingNCT06290934
What this trial is testing

Study of GS-1427 in Participants With Moderately to Severely Active Ulcerative Colitis

Who this might be right for
Ulcerative Colitis
Gilead Sciences 228
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