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Results for “Very-Low Risk Myelodysplastic Syndrome”

23 trials

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Showing 20 of 23 results

Early research (Phase 1)Ended earlyNCT04810611
What this trial is testing

Phase Ib Study of Select Drug Combinations in Patients With Lower Risk MDS

Who this might be right for
Myelodysplastic Syndromes
Novartis Pharmaceuticals 33
Large-scale testing (Phase 3)Ended earlyNCT03263091
What this trial is testing

Efficacy and Safety of Roxadustat for Treatment of Anemia in Participants With Lower Risk Myelodysplastic Syndrome With Low Red Blood Cell Transfusion Burden

Who this might be right for
Primary MDS (Very Low, Low or Intermediate IPSS-R With <5% Blasts)Anemia
Kyntra Bio 184
Post-approval studies (Phase 4)Active Not RecruitingNCT05891249
What this trial is testing

Evaluate the Safety and Effectiveness of Luspatercept for the Treatment of Transfusion-dependent (TD) Anemia Associated With Myelodysplastic Syndromes (MDS) & Beta-thalassemia (β-Thal) in India

Who this might be right for
Anemia
Bristol-Myers Squibb 85
Testing effectiveness (Phase 2)Ended earlyNCT05568225
What this trial is testing

Etavopivat for the Treatment of Anemia in Patients With Myelodysplastic Syndromes (MDS)

Who this might be right for
Very Low Risk, Low Risk, or Intermediate Risk MDS Per IPSS-R
Forma Therapeutics, Inc. 17
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07387354
What this trial is testing

Pacritinib With Aza for Upfront Myelodysplastic Syndrome

Who this might be right for
Myelodysplastic SyndromesMDSMyelodysplastic Syndrome, Unclassifiable+3 more
Thomas Jefferson University 25
Testing effectiveness (Phase 2)Ended earlyNCT05178342
What this trial is testing

Treatment of Anemia in Patients With Very Low, Low or Intermediate Risk Myelodysplastic Syndromes With CA-4948

Who this might be right for
Myelodysplastic SyndromesAnemia
University of Leipzig 38
Testing effectiveness (Phase 2)Active Not RecruitingNCT07052006
What this trial is testing

A Phase 2a Study of HT-6184 in Subjects With IPSS-R Very Low, Low or Intermediate Risk MDS and Anemia

Who this might be right for
Myelodysplastic SyndromeAnemia in Myelodysplastic Syndromes
Halia Therapeutics, Inc. 37
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07319845
What this trial is testing

TAK-226 for Transfusion-Dependent Anemia in Japanese Patients With Lower-Risk Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic Syndromes
Takeda 27
Not applicableApproved For MarketingNCT05937568
What this trial is testing

Expanded Access for Treatment With Imetelstat

Who this might be right for
Myelodysplastic Syndromes
Geron Corporation
Testing effectiveness (Phase 2)Ended earlyNCT02943668
What this trial is testing

Deferasirox in Treating Patients With Very Low, Low, or Intermediate-Risk Red Blood Cell Transfusion Dependent Anemia or Myelodysplastic Syndrome

Who this might be right for
AnemiaMyelodysplastic Syndrome
Fred Hutchinson Cancer Center 2
Testing effectiveness (Phase 2)Ended earlyNCT05237713
What this trial is testing

Efficacy and Safety of Canakinumab for the Treatment of Anemia in LR-MDS Patients

Who this might be right for
AnemiaMyelodysplastic Syndromes
University of Leipzig 10
Testing effectiveness (Phase 2)Study completedNCT03900715
What this trial is testing

An Efficacy and Safety Study of Luspatercept (ACE-536) for the Treatment of Anemia Due to IPSS-R Very Low, Low or Intermediate Risk Myelodysplastic Syndromes (MDS) in Japanese Subjects Who Are Not Requiring Red Blood Cell Transfusion

Who this might be right for
Myelodysplastic Syndromes
Celgene 21
Large-scale testing (Phase 3)Looking for participantsNCT05949684
What this trial is testing

ELEMENT-MDS: A Study to Compare the Efficacy and Safety of Luspatercept in Participants With Myelodysplastic Syndrome (MDS) and Anemia Not Receiving Blood Transfusions

Who this might be right for
Myelodysplastic Syndromes
Bristol-Myers Squibb 360
Large-scale testing (Phase 3)Looking for participantsNCT06499285
What this trial is testing

Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Who Need Regular Blood Transfusions

Who this might be right for
Myelodysplastic Syndromes
Takeda 225
Large-scale testing (Phase 3)Study completedNCT02008318
What this trial is testing

Galunisertib in Participants With Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic Syndromes
Eli Lilly and Company 43
Large-scale testing (Phase 3)Active Not RecruitingNCT03682536
What this trial is testing

Compare the Efficacy and Safety of Luspatercept (ACE-536) Versus Epoetin Alfa for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) Participants Who Require Red Blood Cell Transfusions and Are ESA Naïve

Who this might be right for
Myelodysplastic Syndromes
Celgene 363
Testing effectiveness (Phase 2)Active Not RecruitingNCT04477850
What this trial is testing

Evaluate the Efficacy, Drug Levels and Safety of Luspatercept (ACE-536) for the Treatment of Anemia Due to IPSS-R Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes in Chinese and Japanese Participants With Ring Sideroblasts Who Require Red Blood Cell Transfusions

Who this might be right for
Myelodysplastic Syndromes
Celgene 30
Large-scale testing (Phase 3)Active Not RecruitingNCT06045689
What this trial is testing

Assess Luspatercept in Lower-risk Myelodysplastic Syndrome Participants

Who this might be right for
Myelodysplastic Syndromes
Bristol-Myers Squibb 106
Early research (Phase 1)Study completedNCT04718844
What this trial is testing

A Study Investigate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Response of SLN124 in Adults With Alpha/Beta-thalassaemia and Very Low- and Low-risk Myelodysplastic Syndrome

Who this might be right for
Non-transfusion-dependent ThalassemiaLow Risk Myelodysplastic SyndromeVery-Low Risk Myelodysplastic Syndrome
Silence Therapeutics plc 44
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06594965
What this trial is testing

HS-20106 to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes

Who this might be right for
Myelodysplastic SyndromesAnemiaMDS+1 more
Hansoh BioMedical R&D Company 176
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