Not applicableActive Not RecruitingNCT02783664What this trial is testingEvaluating the Effects of Genetic Testing on Patients' Stress LevelsWho this might be right forBreast Cancer Medical College of Wisconsin 164
Not applicableLooking for participantsNCT04960839What this trial is testingProphylactic Irradiation to the Contralateral Breast for BCAs PatientsWho this might be right forBreast Cancer Second Affiliated Hospital, Zhejiang University, School of Medicine 323
Testing effectiveness (Phase 2)Active Not RecruitingNCT03428802What this trial is testingPembrolizumab in Treating Participants With Metastatic, Recurrent or Locally Advanced Cancer and Genomic InstabilityWho this might be right forBRCA1 Gene MutationBRCA2 Gene MutationLocally Advanced Solid Neoplasm+17 more Rutgers, The State University of New Jersey 21
Not applicableStudy completedNCT00582803What this trial is testingAdherence to Intensive Surveillance for Hereditary Breast CancerWho this might be right forBreast Cancer Memorial Sloan Kettering Cancer Center 85
Not applicableActive Not RecruitingNCT04273542What this trial is testingInterest of Broadband Spectroscopy Analysis by Infrared Laser on Liquid Biopsies in Breast Cancer ScreeningWho this might be right forBreast Cancer FemaleBRCA1 MutationBRCA2 Mutation Centre Jean Perrin 1,100
Not applicableLooking for participantsNCT05129605What this trial is testingProstate Cancer Genetic Risk Evaluation and Screening StudyWho this might be right forProstatic NeoplasmProstate CancerBRCA2 Mutation+5 more Massachusetts General Hospital 400
Not applicableLooking for participantsNCT04294927What this trial is testingTUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of PreventionWho this might be right forBRCA1 Gene MutationBRCA2 Gene MutationRAD51C Gene Mutation+3 more University Medical Center Nijmegen 3,000
Early research (Phase 1)Active Not RecruitingNCT06177171What this trial is testingOlaparib and ASTX727 in BRCA1/2- and Homologous Recombination Deficient (HRD)-Mutated TumorsWho this might be right forBRCA1 MutationBRCA2 MutationBRCA Mutation+3 more Varun Monga, MBBS 13
Testing effectiveness (Phase 2)Looking for participantsNCT04858334What this trial is testingAPOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 MutationWho this might be right forPancreatic Acinar Cell CarcinomaPancreatic Adenosquamous CarcinomaPancreatic Squamous Cell Carcinoma+4 more National Cancer Institute (NCI) 152
Not applicableLooking for participantsNCT02705846What this trial is testingAnalysing Outcomes After Prostate Cancer Diagnosis and Treatment in Carriers of Rare Germline MutationsWho this might be right forProstate Cancer Institute of Cancer Research, United Kingdom 4,260
Not applicableActive Not RecruitingNCT04585074What this trial is testingProspective Study of MAstectomy With Reconstruction Including Robot Endoscopic SurgeryWho this might be right forBreast NeoplasmsGermline BRCA1 Gene MutationGermline BRCA2 Gene Mutation+2 more Severance Hospital 2,000
Not applicableActive Not RecruitingNCT05410951What this trial is testingLobularCard Trial: Searching for Novel Germline Mutations in Lobular Breast Cancer PatientsWho this might be right forLobular Breast CarcinomaLobular in Situ Breast CarcinomaBRCA1 Mutation+1 more European Institute of Oncology 800
Not applicableStudy completedNCT02039388What this trial is testingLavage of the Uterine Cavity for the Diagnosis of Serous Tubal Intraepithelial CarcinomaWho this might be right forOvarian Epithelial CancerCarcinoma in SituOvarian Cancer Medical University of Vienna 701
Not applicableStudy completedNCT03684733What this trial is testingMagnetic Resonance Breast Tissue Characterisation to Improve Risk Stratification for Breast CancerWho this might be right forBRCA1 MutationBRCA2 MutationMammography+1 more Royal Marsden NHS Foundation Trust 28
Post-approval studies (Phase 4)Study completedNCT03495609What this trial is testingUse of Recombinant hCG to Prevent Breast Cancer in BRCA1 and BRCA2 CarriersWho this might be right forhCGBRCA1 MutationBRCA2 Mutation University Hospital, Ghent 33
Testing effectiveness (Phase 2)UnknownNCT04556292What this trial is testingA Phase II Study to Assess the Efficacy and Safety of SC10914 in the Metastatic Breast Cancer PatientsWho this might be right forBreast Cancer MetastaticBRCA 1 Gene MutationBRCA 2 Gene Mutation Jiangxi Qingfeng Pharmaceutical Co. Ltd. 78
Testing effectiveness (Phase 2)Ended earlyNCT03442556What this trial is testingDocetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair DeficiencyWho this might be right forATM Gene MutationBRCA1 Gene MutationBRCA2 Gene Mutation+7 more University of Washington 18
Not applicableStudy completedNCT04890327What this trial is testingWeb-based Family History ToolWho this might be right forGynecologic CancerBreast CancerBRCA1 Mutation+1 more Weill Medical College of Cornell University 250
Testing effectiveness (Phase 2)Study completedNCT03845296What this trial is testingRucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)Who this might be right forDeleterious BRCA1 Gene MutationDeleterious BRCA2 Gene MutationLoss of Heterozygosity+8 more SWOG Cancer Research Network 64
Not applicableStudy completedNCT00381927What this trial is testingEffect of Counseling on Psychological Stress Amongst Women Felt to be at High Risk for Breast Cancer DevelopmentWho this might be right forBreast Cancer Baystate Medical Center 80