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Results for “p53 Mutations”

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Showing 20 of 0 results

Large-scale testing (Phase 3)Study completedNCT01464086
What this trial is testing

LIFSCREEN : Evaluation of Whole Body MRI for Early Detection of Cancers in Subjects With P53 Mutation (Li-Fraumeni Syndrome)

Who this might be right for
Li Fraumeni Syndrome
Gustave Roussy, Cancer Campus, Grand Paris 107
Not applicableStudy completedNCT04976439
What this trial is testing

Patogenic Mutation in 5 Genes

Who this might be right for
Colorectal CancerAPC Gene MutationTP53 Gene Mutation+3 more
Dr Cipto Mangunkusumo General Hospital 22
Not applicableStudy completedNCT00001148
What this trial is testing

Detecting Malignant Brain Tumor Cells in the Bloodstream During Surgery to Remove the Tumor

Who this might be right for
AstrocytomaGlioblastomaGlioma
National Institute of Neurological Disorders and Stroke (NINDS) 25
Not applicableLooking for participantsNCT07419893
What this trial is testing

Germline Genetic Testing of the TP53 Gene

Who this might be right for
TP53 Gene MutationMulti-Gene Transcriptional ProfilingTP53 Gene Germline Mutation Carrier
European Institute of Oncology 1,940
Testing effectiveness (Phase 2)Study completedNCT03732352
What this trial is testing

18F-FDG PET and Osimertinib in Evaluating Glucose Utilization in Patients with EGFR Activated Recurrent Glioblastoma

Who this might be right for
EGFR Gene AmplificationEGFR Gene MutationGlioblastoma+3 more
Jonsson Comprehensive Cancer Center 12
Testing effectiveness (Phase 2)UnknownNCT00082979
What this trial is testing

Duct Endoscopy in Assessing Cellular Atypia in the Breast Duct Fluid of Women With a Genetic Risk for Breast Cancer

Who this might be right for
Breast Cancer
Royal Marsden NHS Foundation Trust 60
Early research (Phase 1)Study completedNCT06054464
What this trial is testing

Investigate the Effects of Acid Reducing Agents on Pharmacokinetics of PC14586 in Healthy Participants

Who this might be right for
Healthy Volunteers
PMV Pharmaceuticals, Inc 28
Early research (Phase 1)Active Not RecruitingNCT02432963
What this trial is testing

Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy

Who this might be right for
Adult Solid NeoplasmBladder CarcinomaColon Carcinoma+14 more
City of Hope Medical Center 11
Early research (Phase 1)Ended earlyNCT05622058
What this trial is testing

ALRN-6924 for Protection of Chemotherapy-Induced Side Effects in Patients With TP53-Mutant Breast Cancer

Who this might be right for
Prevention of Chemotherapy-induced Myelosuppression
Aileron Therapeutics, Inc. 6
Not applicableUnknownNCT04489706
What this trial is testing

Arsenic Trioxide in Recurrent and Metastatic Ovarian Cancer and Endometrial Cancer With P53 Mutation

Who this might be right for
Ovarian CancerEndometrial Cancer
Ruijin Hospital 20
Testing effectiveness (Phase 2)Ended earlyNCT02203513
What this trial is testing

A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, and Metastatic Castrate-Resistant Prostate Cancer

Who this might be right for
Ovarian CancerBreast CancerProstate Cancer
National Cancer Institute (NCI) 111
Testing effectiveness (Phase 2)UnknownNCT04906031
What this trial is testing

Sodium Stibogluconate in the MDS/AML With One of the 65 Defined p53 Mutations

Who this might be right for
Myelodysplastic SyndromesAcute Myeloid LeukemiaMyeloid Malignancy+3 more
First Affiliated Hospital of Jinan University 5
Not applicableNot Yet RecruitingNCT06900582
What this trial is testing

SENTInel Node Mapping Versus Comprehensive Lymphadenectomy in p53-Mutated Endometrial Cancer: A Non-Inferiority Randomized Trial

Who this might be right for
LymphadenectomyEndometrial CancerGene, p53+1 more
University Hospital, Strasbourg, France 374
Very early researchEnded earlyNCT03272633
What this trial is testing

Irradiated Donor Cells Following Stem Cell Transplant in Controlling Cancer in Patients With Hematologic Malignancies

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid Leukemia in RemissionHematopoietic Cell Transplantation Recipient+16 more
Rutgers, The State University of New Jersey 2
Not applicableNot Yet RecruitingNCT07535840
What this trial is testing

A Clinical Trial of Firsekibart, Tislelizumab, and Lenvatinib in Patients With Unresectable, TP53-Mutated Hepatocellular Carcinoma

Who this might be right for
HCC - Hepatocellular CarcinomaTP53 Gene MutationUnresectable+1 more
Tongji Hospital 25
Testing effectiveness (Phase 2)UnknownNCT04869475
What this trial is testing

Arsenic Trioxide in Refractory Solid Tumors With Rescuable p53 Mutation

Who this might be right for
Refractory Solid Tumors
Ruijin Hospital 20
Testing effectiveness (Phase 2)Study completedNCT02272790
What this trial is testing

Adavosertib Plus Chemotherapy in Platinum-Resistant Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Who this might be right for
Ovarian, Fallopian Tube, Peritoneal Cancer, P53 Mutation
AstraZeneca 95
Not applicableStudy completedNCT01675102
What this trial is testing

Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in 17p- Chronic Lymphocytic Leukemia (CLL)

Who this might be right for
CLL
European Society for Blood and Marrow Transplantation 41
Not applicableStudy completedNCT07722819
What this trial is testing

ESCC Molecular Subtypes Based on Multidimensional Features of p53 and Their Clinical Significance

Who this might be right for
P53 Mutation in Esophageal Cancer
Ling Zhiqiang 300
Not applicableUnknownNCT06521684
What this trial is testing

Translational Study of MSS, TP53 Mutation and Chromosome Instability Relationship in Endometrial Carcinoma

Who this might be right for
Endometrial NeoplasmsTP53 Gene MutationChromosomal Instability+1 more
Peking Union Medical College Hospital 110
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