Testing effectiveness (Phase 2)Ended earlyNCT06834399What this trial is testingTATE and KN046 in MCRCWho this might be right forColorectal Cancer with Hepatic Metastases Zhejiang Raygene Pharmaceuticals Co., Ltd 42
Testing effectiveness (Phase 2)Looking for participantsNCT07079631What this trial is testingA Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment BNT327 and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal CancerWho this might be right forMetastatic Colorectal Cancer BioNTech SE 482
Testing effectiveness (Phase 2)Looking for participantsNCT06911684What this trial is testingRadiotherapy Plus Iparomlimab and Tuvonralimab (QL1706), Regorafenib, and CAPOX as Neoadjuvant Therapy for pMMR/MSS LARC.Who this might be right forRectal Cancer Patients Sun Yat-sen University 88
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07106034What this trial is testingStandard Second-line Therapy With ONgericimab and TOripalimab in pMMR/MSS Colorectal Cancer: a Single-arm Phase II TrialWho this might be right forAdvanced Colorectal Cancer Shanghai Pudong Hospital 32
Testing effectiveness (Phase 2)Looking for participantsNCT06923345What this trial is testingModified Long-Course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for MSS/pMMR High-risk Mid/Low LARC (MODIFI-RC-I)Who this might be right forRectal CancerNeoadjuvant TherapiesImmune Checkpoint Therapy+1 more Sixth Affiliated Hospital, Sun Yat-sen University 80
Testing effectiveness (Phase 2)Looking for participantsNCT05815303What this trial is testingXELOX Combined With Cadonilimab Versus XELOX as Neoadjuvant Treatment for Locally Advanced, pMMR Rectal CancerWho this might be right forRectal CancerMSS Cancer Institute and Hospital, Chinese Academy of Medical Sciences 92
Testing effectiveness (Phase 2)Ended earlyNCT05733611What this trial is testingRP2/RP3 in Combination With Atezolizumab and Bevacizumab for the Treatment of Patients With CRCWho this might be right forRefractory Metastatic Colorectal CancerpMMRMSS Replimune Inc. 5
Testing effectiveness (Phase 2)Looking for participantsNCT06829355What this trial is testing"Thymalfasin Immunotherapy Study with Triple Regimen in Advanced MSS/pMMR Colorectal Cancer"Who this might be right forMCRC Beijing Friendship Hospital 52
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07359456What this trial is testingTesting Ivonescimab in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancers Without Liver MetastasesWho this might be right forMetastatic Colorectal Cancer UNICANCER 130
Testing effectiveness (Phase 2)Looking for participantsNCT07279077What this trial is testingNode-Sparing Low-Dose Radiotherapy Concurrent With Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Single-Arm, Phase II TrialWho this might be right forColon CancerNeoadjuvant TherapiesImmune Checkpoint Therapy+1 more Sixth Affiliated Hospital, Sun Yat-sen University 38
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06484153What this trial is testingFruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Advanced or Metastatic pMMR/MSS Colorectal CarcinomaWho this might be right forTo Evaluate the Efficacy of Fruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Colorectal CarcinomaTo Evaluate Whether Pirfenidone Can Reshape the Tumor Microenvironment in Colorectal CancerCombination of Fruquintinib and Anti-PD-1 Antibody Was Reported to Improve Patient Prognosis in Colorectal Cancer Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Testing effectiveness (Phase 2)WithdrawnNCT05582031What this trial is testingRegorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable CancersWho this might be right forAnal Squamous Cell CarcinomaColorectal NeoplasmsSoft Tissue Sarcoma+5 more Translational Research in Oncology
Testing effectiveness (Phase 2)Looking for participantsNCT06885385What this trial is testingStudy Evaluating the Safety and Efficacy of JS207 With or Without JS015 in Combination With Chemotherapy in Patients With Colorectal CancerWho this might be right forAdvanced Colorectal Cancer Shanghai Junshi Bioscience Co., Ltd. 60
Not applicableNot Yet RecruitingNCT06504875What this trial is testingApplication of PD-1 Monoclonal Antibody in Combination With IL-2 and CapeOX in Organ Preservation Therapy for Ultra-Low Localized Advanced Rectal CancerWho this might be right forRectal Cancer The First Affiliated Hospital with Nanjing Medical University 23
Testing effectiveness (Phase 2)Active Not RecruitingNCT04833387What this trial is testingPD-1 Antibody Following Preoperative Chemoradiotherapy for Locally Advanced pMMR/MSS Rectal CancerWho this might be right forColorectal Carcinoma Sun Yat-sen University 30
Early research (Phase 1)Not Yet RecruitingNCT07411781What this trial is testingPIN in Combination With Sintilimab in Previously Treated pMMR/MSS CRC With Hepatic MetastasesWho this might be right forColorectal CancerAdult Chinese PLA General Hospital 25
Testing effectiveness (Phase 2)Looking for participantsNCT06930118What this trial is testingThe Aim of This Study is to Assess the Efficacy and Safety of Chidamide, Regorafenib in Combination With Iparomlimab and Tuvonralimab for the Treatment of Advanced Colorectal Cancer in Third-line Therapy and Subsequent Lines.Who this might be right forAdvanced Colorectal Cancer in the Third-line Treatment and BeyondpMMR/MSS Advanced Colorectal Cancer Shanghai Changzheng Hospital 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06218888What this trial is testingA Phase II Clinical Study of the Efficacy and Safety of Tislelizumab Combined With Fruquintinib and Chidamide in the Treatment of Unresectable or Advanced Microsatellite Stabilized (MSS/pMMR) Colorectal Cancer With Liver MetastasesWho this might be right forColo-rectal Cancer Fujian Cancer Hospital 17
Testing effectiveness (Phase 2)Looking for participantsNCT06949111What this trial is testingRadiotherapy + Systemic Therapy as Conversion Therapy for pMMR/MSS T4M0 Colon Cancer（Neo-Color）Who this might be right forColon Cancer Hebei Medical University Fourth Hospital 128
Testing effectiveness (Phase 2)Looking for participantsNCT05669430What this trial is testingGV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor MalignanciesWho this might be right forSolid Tumor, AdultRefractory CancerEndometrial Carcinoma (EC)+4 more GV20 Therapeutics 365